Clinical trials: Development and Health
Child Developmental Delay, Child Development
CASITA Intervention for Children at Risk of Delay in Carabayllo, Peru
Building on an intervention for early child development from the SPARK Center in Boston, Socios En Salud (SES) pilot tested "CASITA" a community-based package to screen and treat young children (ages 1-3 years of age) diagnosed…
- Conditions
- Child Developmental Delay, Child Development, Community Health Workers, Low Income Population
- Trial name
- NCT03010306
- Testing
- CASITA
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
The Emergency Response Capabilities of Nurses (Including Occupational Protection, Critical Thinking, Communication Skills and Humanistic Care, Etc.)
Development and Evaluation of a Large Language Model - Based Training Program for Nurses in Public Health Emergencies
The goal of this randomized controlled trial is to evaluate the immediate efficacy of a Large Language Model (LLM)-assisted training program in enhancing nurses' emergency response capabilities in 204 practicing nurses with ≤5…
- Trial name
- NCT07141433
- Testing
- LLM-Assisted Public Health Emergency Training Program, Standard Public Health Emergency Training Program
- Where
- China
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- The Affiliated Hospital Of Guizhou Medical University
Frailty, Cardiovascular Diseases
MultiMorbidity Life-Course Approach To Myocardial Health -A Cardiac Sub-Study of the MRC National Survey of Health and Development (NSHD)
Background The life course accumulation of overt and subclinical myocardial dysfunction contributes to older age mortality, frailty, disability and loss of independence.
- Trial name
- MyoFit46 (NCT05455125)
- Testing
- CMR CGI
- Where
- United Kingdom
- Volunteers
- 550 people
- Sponsor
- University College, London
Sleep
Testing and Development of a Sleep Training Mobile Health Application
The specific aims of this study are : 1) To pilot test the alpha build prototype of the sleep training smartphone application using a sample of parents looking for sleep training advice online.
- Trial name
- NCT02718196
- Testing
- Sleep Training smartphone application
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Child Development
LIFE Child (LIFE Leipzig Research Centre for Civilization Diseases)
The Leipzig Research Centre for Civilization Diseases (LIFE) Child Study is a prospective longitudinal population-based study with a life course approach to health and disease.
- Trial name
- NCT02550236
- Where
- Germany
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Weight Gain, Maternal; Diabetes Mellitus, Affecting Fetus
Tongji Maternal and Child Health Cohort
This is a population-based study to obtain data for the evaluation of current used recommendations for weight gain during pregnancy released by IOM (2007) and investigate the association between maternal diet and the health…
- Conditions
- Weight Gain, Maternal; Diabetes Mellitus, Affecting Fetus, Diet Habit, Pregnancy Complications
- Trial name
- TMCHC (NCT03099837)
- Volunteers
- 8,649 people
- Sponsor
- Huazhong University of Science and Technology
Obesity, Weight Gain
Diet, Physical Activity and Breastfeeding Intervention on Maternal Nutrition, Offspring Growth and Development
NCDs are observed mostly in adults, however there is strong evidence that suggests NCDs origin early in life, thus the first 1000 days of life (conception to age 2yrs).
- Conditions
- Obesity, Weight Gain, Metabolic Diseases, Birth Weight
- Trial name
- NCT01916603
- Testing
- Normative Intervention
- Where
- Chile
- Volunteers
- 2,400 people
- Sponsor
- University of Chile
Short Stature, Short; Stature, Psychosocial
Short Stature and Psychological Well-being
The first aim of the present study is to evaluate the psychological impact of the condition of short stature (family) in a sample of Italian children, comparing them with subjects of normal stature, measuring their levels of…
- Trial name
- PSICOSHORT (NCT06295341)
- Testing
- Recombinant human growth hormone (only for children with growth hormone deficiency)
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Nutritional Deficiencies
Development and Health of Rural Chinese Children Fed Meat as a Daily Complementary Food From 6-18 Mos of Age
Inadequate feeding of infants and toddlers impairs physical and cognitive development and is a major contributor to early childhood infectious disease illnesses and preventable mortality.
- Trial name
- NCT00726102
- Testing
- Meat, Cereal, fortified rice cereal
- Where
- United States
- Volunteers
- 1,488 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Autism Spectrum Disorder, Executive Functioning
Hybrid Effectiveness-Implementation Trial of an Executive Functioning Intervention for Children's Mental Health Services
This project aims to follow up on a prior project examining the impact of training therapists in an executive functioning intervention Unstuck and On Target (UOT) adapted for community mental health settings.
- Trial name
- NCT06651086
- Testing
- Unstuck and On Target, Unified Protocol for Children
- Where
- 2 sites in United States
- Volunteers
- 672 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Adolescent Development
Adolescent Transition West Africa
This trial will serve as an outcome evaluation of 'Adolescent Transition in West Africa' (ATWA), a school-based program in Mali, Burkina Faso, and Niger for adolescents ages 10-19.
- Trial name
- ATWA (NCT05396664)
- Testing
- ATWA
- Where
- 3 sites in Burkina Faso, Mali and 1 more
- Volunteers
- 4,300 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Malaria
Micronutrients and Child Health Study
The purpose of this study is to determine to what extent supplementation with zinc and other micronutrients are efficacious in preventing malaria in young Tanzanian children.
- Trial name
- MACH (NCT00623857)
- Testing
- Zinc, Vitamins and minerals other than zinc, Vitamins plus zinc and other minerals
- Where
- Tanzania
- Volunteers
- 612 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Healthy
Gastrointestinal Tolerance And General Health Status Of Healthy Term Infants Fed A New Infant Formula
The purpose of this study is to assess stool consistency, in combination with additional health-related parameters including gastrointestinal tolerance and health-related quality of life, in a large sample of Chinese infants.
- Trial name
- NCT01370967
- Testing
- Study formula feeding, Human milk feeding, Mixed feeding
- Where
- 24 sites in China
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Anxiety, Autism Spectrum Disorder
Adaptation and Feasibility of the Community-Based Anxiety Program Tailored for Autism (CAPTA)
Anxiety is very common in autistic youth. Recently, an intervention has been created by the investigators to target these symptoms in autistic youth in a community setting.
- Conditions
- Anxiety, Autism Spectrum Disorder, Separation Anxiety, Generalized Anxiety Disorder
- Trial name
- NCT06046170
- Testing
- Cognitive Behavioral Therapy, Treatment as Usual
- Where
- 3 sites in United States
- Volunteers
- 32 people
- Sponsor
- Baylor College of Medicine
Cerebral Palsy
Effects of Routine Physical Therapy With and Without Neurodevelopmental Technique on GMF, Spasticity and HRQOL in Diplegic CP
The aim of this study is to investigate the effects of routine physical therapy with and without neurodevelopmental technique on gross motor function, spasticity and health related quality of life in diplegic cerebral palsy.
- Trial name
- NCT06444230
- Testing
- Routine Physical therapy with Neurodevelopmental technique, Routine Physical therapy
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- University of Lahore
Autism Spectrum Disorder, Executive Function
The Effect of Cognitive Orientation Approach on Daily Occupational Performance With Autism Spectrum Disorder
The goal of this clinical trial is by using the Cognitive Orientation Approach on Daily Occupational Performance, which is also supported by the literature and applied by occupational therapists, in children diagnosed with Autism…
- Conditions
- Autism Spectrum Disorder, Executive Function, Patient Participation
- Trial name
- NCT06038435
- Testing
- Cognitive Orientation Approach, Ayres Sensory Integration Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Bezmialem Vakif University
Autism Spectrum Disorder, Obesity
Mobile Health Intervention for Children With Autism
This study is a randomized clinical trial conducted in China from January 2023 to July 2025. It aims to test whether a mobile health program delivered via WeChat, with or without additional human support, can help improve body…
- Conditions
- Autism Spectrum Disorder, Obesity, Pediatric Overweight
- Trial name
- WeChat-Autism (NCT07514910)
- Testing
- Standard Lifestyle Recommendations, WeChat-Based Mobile Health Intervention, Coach-Facilitated Tele-Group Sessions
- Where
- China
- Volunteers
- 276 people
- Sponsor
- Hunan Normal University
Preterm Birth, Pediatric Cancer
eHealth as an Aid for Facilitating and Supporting Self-management in Families With Long-term Childhood Illness
The overall aim is twofold: 1) to stretch the borderline regarding the present knowledge of clinical and economic cost-effectiveness of eHealth as an aid for facilitating and supporting self-management in families with long-term…
- Conditions
- Preterm Birth, Pediatric Cancer, Hirschsprung Disease, Congenital Malformation
- Trial name
- eChildHealth (NCT04150120)
- Testing
- e-health device with application, Mobile phone text messaging, early detection of cerebral palsy using a mobile phone application
- Where
- 7 sites in Denmark, Ethiopia and 1 more
- Volunteers
- 720 people
- Sponsor
- Lund University
Children Behavior Problem, Pregnancy
Relationship About Pregnancy Health and Offspring Developmental &Behavioral Outcomes
This topic puts forward a hypothesis: genetic and environmental factors such as major depressive disorder during pregnancy, nutritional status of vitamin A, D, E, and folic acid, intestinal microecology, and bisphenol A exposure…
- Trial name
- APCSAHAODBO (NCT04017286)
- Where
- 5 sites in China
- Volunteers
- 3,000 people
- Sponsor
- Chen Li
Autism Spectrum Disorder (ASD), Attention Deficit Hyperactivity Disorder (ADHD)
Physiotherapy for Improving Mental Health in Children and Adolescents With ASD and ADHD
This study investigates whether a structured physiotherapy program can help reduce symptoms of stress, anxiety, and depression in children and adolescents diagnosed with Autism Spectrum Disorder (ASD) or…
- Conditions
- Autism Spectrum Disorder (ASD), Attention Deficit Hyperactivity Disorder (ADHD), Neurodevelopmental Disorders
- Trial name
- NCT07231354
- Testing
- Structured Physiotherapy Program
- Where
- Greece
- Volunteers
- 117 people
- Sponsor
- International Hellenic University