Clinical trials: Development and Health
Offspring, Adult, Lifestyle
Factors Affecting Newborn Body Composition and Later Health in Helsinki Birth Cohort 2018-2022
In Helsinki Birth Cohort 2018-2022 a large, longitudinal and well-phenotyped birth cohort of infants and their parents will be established.
- Conditions
- Offspring, Adult, Lifestyle, Obesity, Childhood, Pregnancy Related
- Trial name
- HeBiCo (NCT03765684)
- Where
- Finland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Developmental Delay
Improving Neurodevelopmental ouTcomes After Prenatal Cannabinoid in uTero Exposure
The INTACT trial is a multisite pilot feasibility study aimed at testing the effectiveness of the INTACT Intervention program in improving neurodevelopmental outcomes in infants prenatally exposed to cannabinoids.
- Trial name
- INTACT (NCT06423664)
- Testing
- Play and Learn Strategies (PALS) Program
- Where
- 3 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- IDeA States Pediatric Clinical Trials Network
Cognition
Indoor Air Quality Monitoring and Impact on Children's Health
This study aims at understanding the relation between indoor air quality in schools, including both chemical and microbiological determinants, and cognition in children by gathering data across different parts of Europe
- Trial name
- LEARN (NCT06197477)
- Testing
- OurAir SQ 1750 - Mobile Air Purification System for indoor
- Where
- Belgium
- Volunteers
- 900 people
- Sponsor
- Hasselt University
Feeding; Difficult, Newborn, Premature Infant Disease
Psychometric Properties of the SMART Feeding Tool
This observational study aims to evaluate the psychometric properties of a new infant feeding tool called "SMART Tool" in the neonatal intensive care unit. The main questions it aims to answer are: 1.
- Conditions
- Feeding; Difficult, Newborn, Premature Infant Disease, Dysphagia of Newborn, Nurse's Role
- Trial name
- NCT05729828
- Where
- 4 sites in United States
- Volunteers
- 76 people
- Sponsor
- Wake Forest University Health Sciences
Maternal Psychological Distress, Prenatal Stress
Roo Study on Mom and Baby Well-Being
This study employs a randomized controlled trial of an established intervention, Mindfulness Based Cognitive Therapy (MBCT) adapted for pregnancy, to examine effects on various aspects of maternal psychological stress during…
- Conditions
- Maternal Psychological Distress, Prenatal Stress, Infant Development, Functional Neuroimaging
- Trial name
- NCT03809598
- Testing
- Mindfulness Based Cognitive Therapy
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Healthy Lifestyle Behaviors, Overweight Adolescents
Healthy Living in Overweight and Obese Adolescents ASGE-FABES Program in Development of Formats
The aim of this project is to develop multiple behavioral strategies for the prevention of obesity in adolescents. ASGE-FABES [Adolescent Health Promotion Physical Activity, Physical activity of overweight and obese youth of…
- Conditions
- Healthy Lifestyle Behaviors, Overweight Adolescents, Obese Adolescents
- Trial name
- NCT04794244
- Testing
- ASGE-FABES Program
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- aysun ardıç
Molar Incisor Hypomineralization
Change in OHRQOL Following Minimally Invasive Treatment of Anterior Teeth in Children With MIH
MIH is a prevalent developmental defect which has a negative impact on children's OHRQoL, especially when incisor opacities are present.
- Trial name
- NCT05727475
- Testing
- Minimal invasive restorative treatment, Fluoride gel application
- Where
- Jordan
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
HIV, HIV - Human Immunodeficiency Virus
Intervention to Reduce HIV Related Stigma Among Pregnant and Postpartum Women
Purpose of this Study: The main purpose of this study is to adapt an existing evidence-based intervention, Project Accept Post-Test Support Services (PTSS) Module 3, specifically for pregnant and postpartum women living with HIV…
- Conditions
- HIV, HIV - Human Immunodeficiency Virus, Postpartum, Pregnancy
- Trial name
- WAT (NCT07064928)
- Testing
- Adapted Project Accept's Post-Test Support Services (PTSS) Module 3
- Where
- Ghana
- Volunteers
- 163 people
- Sponsor
- University of California, San Francisco
Asthma (Diagnosis), Children
Asthma Health Literacy Scale for Children (AHLSC) (Aged 8-12)
Asthma Health Literacy Scale for Children (AHLCS) (Ages 8-12): A Scale Development Study Objective: This study will be conducted using a methodological design to develop and examine the psychometric properties of the Asthma…
- Conditions
- Asthma (Diagnosis), Children, Health Literacy, Scale Reliability Validity
- Trial name
- NCT07295249
- Testing
- Asthma Health Literacy Scale for Children (AHLSC) (Aged 8-12): A Scale Development Study
- Where
- Turkey (Türkiye)
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- University of Yalova
Knowledge, Behavior
Socialization To Enrich Participation & Support Sexuality for Young People With I/DD
The goal of this clinical trial is to test the effectiveness of a 6-week socialization and sex education curriculum (STEPS2) in young people (aged 16-27 years) with intellectual and developmental disabilities (I/DD), including…
- Trial name
- STEPS2 (NCT06231485)
- Testing
- STEPS2, STYH
- Where
- United States
- Volunteers
- 856 people, healthy volunteers welcome
- Sponsor
- City University of New York, School of Public Health
Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder
Teacher Help for Children and Youth With Mental Health Disorders
Currently, Canadian school systems are struggling to meet the needs of children with mental health disorders. It is particularly challenging to meet the needs of students with neurodevelopmental disorders (NDDs) within the…
- Conditions
- Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder, Learning Disabilities
- Trial name
- TeacherHelp (NCT02919215)
- Testing
- Teacher Help Intervention
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- IWK Health Centre
HIV, Adolescent Development
Health Improvement for Baltimore Youth
Preliminary data from the investigators' National Center for Complementary and Alternative Medicine (NCCAM)-funded R21 on mindfulness-based stress reduction (MBSR) in HIV-infected youth suggest an association between mindfulness…
- Conditions
- HIV, Adolescent Development, Adolescent Behavior, Medication Adherence
- Trial name
- NCT02624193
- Testing
- MBSR Program, HT Program
- Where
- 2 sites in United States
- Volunteers
- 97 people
- Sponsor
- Johns Hopkins University
SIDS, Infant Development
Improving Infant Sleep Safety With the Electronic Health Record
This research is being done to find out if individualized feedback provided to parents on safe infant sleep can improve safety. This will be accomplished by having parents send photographs of their baby sleeping through the…
- Trial name
- NCT03662048
- Testing
- Safe
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Autism Spectrum Disorder, Suicidal Ideation
Adapted Visual Safety Plan for Autistic Youth (VSP-AY) to Address Self-harm, Suicidal Ideation, and Suicide Behaviors
This pilot randomized controlled trial will recruit 90 autistic adolescents aged 13-18 years with recent suicidal thoughts or behaviors from Geha Mental Health Center in Israel.
- Conditions
- Autism Spectrum Disorder, Suicidal Ideation, Suicidal Behavior, Self-Injurious Behavior
- Trial name
- VSP-AY (NCT07333014)
- Testing
- Adapted Visual Safety Plan for Autistic Youth (VSP-AY) to Address Self-harm, Suicidal Ideation, and Suicide Behaviors
- Where
- Israel
- Volunteers
- 90 people
- Sponsor
- College of Management Academic Studies
Adolescent Social and Emotional Development
Social and Emotional Development Support Program for Adolescents: Effects on Belonging, Meaning in Life, Authenticity, Well-Being, and Resilience
This study aims to examine the effectiveness of the Social and Emotional Developmental Support Program on adolescents' sense of belonging, meaning in life, emotional authenticity, well-being, and resilience.
- Trial name
- SEDESP (NCT07253636)
- Testing
- Social and Emotional Developmental Support Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Obsessive-Compulsive Disorder
Developing Adaptive Treatment Strategies for Children and Adolescents With Obsessive-compulsive Disorder.
Obsessive-compulsive disorder affects approximately 2% of the population, frequently has its onset during childhood or adolescence and is potentially incapacitating.
- Trial name
- SMART (NCT01148316)
- Testing
- fluoxetine, Group cognitive-behavioral therapy
- Where
- Brazil
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Roseli Shavitt
Enamel Hypomineralization, Tooth Erosion
Hydroxyapatite Toothpastes and Enamel Remineralization:
This randomized controlled clinical trial aims to evaluate the efficacy of two commercially available toothpastes containing hydroxyapatite in the remineralization of early enamel lesions.
- Trial name
- HEREMI (NCT07069218)
- Testing
- Biorepair® Total Protection Plus Toothpaste, Bioniq® Toothpaste
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
Alcohol Misuse
Development and Evaluation of a Theory and Evidence-based Intervention to Reduce Hazardous Alcohol Consumption Among Treatment Seeking Smokers
This study will evaluate the implementation of a fully automated, direct-to-patient digital alcohol intervention embedded within the STOP Program's patient portal.
- Trial name
- NCT07228923
- Testing
- Brief alcohol intervention
- Where
- Canada
- Volunteers
- 77 people
- Sponsor
- Centre for Addiction and Mental Health
Developmental Disability, Intellectual Disability
Effect of Sensory Adapted Dental Environment on Dental Anxiety of Children With Intellectual and Developmental Disabilities
Children with intellectual/developmental disabilities (ID/DD) will experience less dental anxiety and cooperate better in a Sensory Adapted Dental Environment (modified visual, sensory, and somatosensory stimuli in a regular…
- Conditions
- Developmental Disability, Intellectual Disability, Dental Anxiety
- Trial name
- NCT03218462
- Testing
- Sensory Adapted Dental Environment (SADE)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Virginia Commonwealth University
Anxiety, Depression
Metacognitive Therapy for Common Mental Health Problems in Autistic CYP: A Case Series
Anxiety and Depression are common in young people (CYP) and especially in CYP with a diagnosis of Autism. Autistic people often say therapy has not been adapted to meet their needs.
- Trial name
- NCT05980143
- Testing
- Metacognitive Therapy
- Where
- 2 sites in United Kingdom
- Volunteers
- 5 people
- Sponsor
- University of Manchester