Clinical trials: Development and Health
Suicide, Mental Health Disorder
A Digitally Assisted Risk Reduction Platform for Youth at High Risk for Suicide
Despite efforts to prevent suicide, US rates are climbing, and suicide is the second leading cause of death among youth. Digital tools, especially personal smartphones, are promising avenues to address these issues and can be…
- Conditions
- Suicide, Mental Health Disorder, Anhedonia
- Trial name
- NCT05920252
- Testing
- Vira, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Ksana Health
Idiopathic Scoliosis
Development and Validation of the MOBI Questionnaire
Scoliosis is a common spinal deformity in adolescents. Orthopedic brace treatment is the only conservative (nonsurgical) treatment effective in limiting the progression of this deformity.
- Trial name
- MOBI (NCT03929614)
- Testing
- MOBI validation
- Where
- Canada
- Volunteers
- 176 people
- Sponsor
- St. Justine's Hospital
Overweight, Physical Activity
The Healthy Elementary School of the Future
Unhealthy lifestyles in early childhood are a major global health challenge. These lifestyles often persist from generation to generation and contribute to a vicious cycle of health-related and social problems.
- Conditions
- Overweight, Physical Activity, Malnutrition, Child Development
- Trial name
- THESF (NCT02800616)
- Testing
- The Healthy Primary School of the Future, The Physical Activity School
- Volunteers
- 2,349 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Exostoses, Multiple Hereditary
The Health-Related Quality of Life in Patients With Hereditary Multiple Exostoses
The purpose of this study is to assess the health-related quality of life of subjects who have Hereditary Multiple Exostoses and to develop a disease specific quality of life survey.
- Trial name
- NCT00474448
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Mental Health
Empowering Newcomer Voices: A Trauma-Informed, Gender-Responsive Group Intervention in Schools (VOCES-NUEVAS)
The goal of this study is to see if VOCES-NUEVAS, a school-based program for newcomer girls from Latin America, is helpful and easy to use.
- Trial name
- VOCES-NUEVAS (NCT07041931)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Hemophilia
Motor Proficiency of People With Bleeding Disorders Using the BOT-2 (TM)
The purpose of this study is to find out if gross motor skills of children and young adults with bleeding disorders are different from those without bleeding disorders.
- Trial name
- NCT02279199
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Obesity, Health Promotion
A Health Promotion Intervention for Vulnerable School
The BeE-school (Be Empowered in school) is a cluster-randomised trial that addresses the complexity of the social challenge (vulnerable school-age children).
- Conditions
- Obesity, Health Promotion, Noncommunicable Diseases, Child Development
- Trial name
- BeE-school (NCT05395364)
- Testing
- Intervention program BeE-school
- Where
- Portugal
- Volunteers
- 735 people
- Sponsor
- University of Minho
Chronic Pain
Effectiveness and Implementation of a Digital Intervention for Pediatric Chronic Pain Co-designed With Patients
Children and adolescents with chronic pain often lack a proper diagnosis and treatment. Research has shown that, if left untreated, it usually doesn't resolve and continues through adulthood.
- Trial name
- Digital SPA (NCT05917626)
- Testing
- Digital SPA
- Where
- 6 sites in Spain
- Volunteers
- 195 people
- Sponsor
- University of Malaga
Child Development, Child Behavior
Effects of Psychosocial Stimulation and Cash on Children's Development and Behaviour
Burden: In developing countries, an estimated 219 million children do not reach their maximum potentiality because of poverty and associated risk factors.
- Trial name
- NCT03281980
- Testing
- Psychosocial stimulation (PS), Government Intervention (UCT+HE)
- Where
- Bangladesh
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Palliative Care, Primary Health Care
Primary Care Consultation for Patients With Palliative Care Needs
Introduction General practitioners provide health care in the community, managing patients and families longitudinally, and there is some evidence that when they are involved in caring for people with palliative care needs…
- Trial name
- NCT05244590
- Testing
- Consultation model for patients with palliative care needs
- Where
- Portugal
- Volunteers
- 53 people
- Sponsor
- University of Coimbra
Diabetes, Hypertension
Pharmacists Improving Refugees' Adherence and Knowledge of Their Chronic Medications
This study is a randomized, controlled, single-blinded clinical study which conducted over six months (May to October 2016) in different Jordanian cities, where most of Syrian refugees reside.
- Conditions
- Diabetes, Hypertension, Dyslipidemias, Cardiac Disease
- Trial name
- NCT04554810
- Testing
- Medication Management Service
- Volunteers
- 106 people
- Sponsor
- Prof. Iman Basheti
Preterm Birth, Pediatric Cancer
eHealth as an Aid for Facilitating and Supporting Self-management in Families With Long-term Childhood Illness
The overall aim is twofold: 1) to stretch the borderline regarding the present knowledge of clinical and economic cost-effectiveness of eHealth as an aid for facilitating and supporting self-management in families with long-term…
- Conditions
- Preterm Birth, Pediatric Cancer, Hirschsprung Disease, Congenital Malformation
- Trial name
- eChildHealth (NCT04150120)
- Testing
- e-health device with application, Mobile phone text messaging, early detection of cerebral palsy using a mobile phone application
- Where
- 7 sites in Denmark, Ethiopia and 1 more
- Volunteers
- 720 people
- Sponsor
- Lund University
Developmental Delays
A Family Centered Intervention to Promote Optimal Child Development
This is a randomized controlled trial aimed at assessing the effectiveness of a patient decision aid (PDA) and text message reminder in promoting early intervention referral completion when infants and toddlers are identified…
- Trial name
- NCT01941186
- Testing
- Patient Decision Aid
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Children's Hospital of Philadelphia
Noncompliance
Efficacy of Parent-Child Interaction Therapy With Autism Spectrum Disorder
The aim of the current proposal is to determine if the PCIT treatment manual can be successfully utilized for preschoolers with ASD and disruptive behavior (across a range of intellectual functioning levels) and to evaluate its…
- Trial name
- PCIT (NCT02088905)
- Testing
- Parent Child Interaction Therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Pittsburgh
Suicide Attempt, Depression
Effects of a Multifaceted School-Based Intervention to Protect Mental Health and Prevent Suicidal Behaviour in Adolescents in Spain
What is this study about? This study aims to find out if a school-based program can help improve mental health and prevent suicidal thoughts and behaviors in teenagers in Spain.
- Conditions
- Suicide Attempt, Depression, Adolescent Mental Health, Self-Harm
- Trial name
- NCT06996054
- Testing
- Multifaceted School-Based Mental Health and Suicide Prevention Program
- Volunteers
- 2,280 people, healthy volunteers welcome
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
Intellectual Disability
Improving the Health of Parents and Their Adolescent and Transition-age Youth With Intellectual and Developmental Disabilities
This study will determine the comparative effectiveness of Go Act, a tailored advocacy curriculum versus Peer parent-directed peer learning for increasing parent activation for parents of youth with intellectual and developmental…
- Trial name
- NCT05986305
- Testing
- Go Act, Peer
- Where
- 2 sites in United States
- Volunteers
- 406 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Preimplantation Genetic Testing (PGT), Frozen Embryo Transfer Cycle
Effects of Trophectoderm (TE) Biopsy on the Health and Development of Children Born After Preimplantation Genetic Testing (PGT) Cycles.
This study aims to investigate the effects of trophectoderm (TE) biopsy on the health and development of children born after preimplantation genetic testing (PGT) cycles.
- Conditions
- Preimplantation Genetic Testing (PGT), Frozen Embryo Transfer Cycle, Assisted Reproduction Technologies, Postnatal Health
- Trial name
- NCT07349966
- Testing
- Questionnaire
- Where
- Italy
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Parenting, Child Development
Room to Grow Evaluation for Children
This research project is a small-scale randomized controlled trial (RCT) of an innovative program based in New York City called Room to Grow (RtG).
- Trial name
- RTG (NCT04226053)
- Testing
- Parenting, Child Development
- Where
- United States
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- Columbia University
Osteogenesis Imperfecta
e-Health Care Method for Patients With Osteogenesis Imperfecta (Tele OI)
This work seeks to formalize the association between the use of technology and the effective treatment of patients with Osteogenesis Imperfecta, which has not yet been explored in the literature; and aims to prove functional…
- Trial name
- Tele OI (NCT06555536)
- Testing
- Tele OI
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- Paulo Humberto Mem Martendal Vallandro Costa
Depression - Major Depressive Disorder, Bipolar
Behavioural Development, Long-term Outcomes and Opportunities to Optimize Youth Mental Health Trajectories
Behavioural Development, Long-term Outcomes and Opportunities to Optimize Youth Mental Health (BLOOM) is a project that aims to overcome age and diagnostic boundaries to generate person-specific longitudinal profiles of mental…
- Conditions
- Depression - Major Depressive Disorder, Bipolar, Psychosis, Eating Disorder NOS
- Trial name
- BLOOM (NCT06978452)
- Where
- Canada
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Douglas Mental Health University Institute