Clinical trials: Developmental Disorder
Autism Spectrum Disorder
Modular Approach for Autism Programs in Schools
The number of students aged 6-21 years with an educational classification of autism spectrum disorder (ASD) in the United States grew by about 19 times over a 19-year period-from 29,076 in 1995-6 to 545,198 in 2014-2015 (IDEA…
- Trial name
- MAAPS (NCT04533607)
- Testing
- MAAPS
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- May Institute
Autism Spectrum Disorder, Movement Disorders
Database Of Clinical Data For Individuals With Variants In The IRF2BPL Gene
This protocol serves as a data collection tool for individuals with variants (missense, nonsense, frameshifts) in the IRF2BPL gene (MIM 611720), which causes Neurodevelopmental Regression, Seizures, Autism and Developmental Delay…
- Conditions
- Autism Spectrum Disorder, Movement Disorders, Seizures, Dystonia
- Trial name
- IRF2BPL (NCT03892798)
- Testing
- No interventions are planned
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Developmental Dysplasia of the Hip, Hip Dysplasia
Sequelae of Developmental Dysplasia of the Hip
The aim of this study is to assess long term effects of developmental dysplasia of the hip (DDH) to overall health and quality of life later in life.
- Trial name
- NCT02431871
- Where
- Finland
- Volunteers
- 340 people
- Sponsor
- University of Oulu
Solid Tumor, Childhood, Brain Tumor, Pediatric
Social Emotional Development in Young Children With Cancer
Many children with cancer are diagnosed in early childhood, and as such, will likely miss key social experiences such as participation in preschool or kindergarten, playing on playgrounds, and other normative experiences.
- Trial name
- NCT03086421
- Testing
- Questionnaires
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- St. Jude Children's Research Hospital
PolG, Primary Mitochondrial Myopathy
Mitochondrial Video Assessment Source Material Study
Source material collection of videos to develop the Mitochondrial Video Assessment (MVA) for patients with mitochondrial myopathies.
- Trial name
- NCT06180421
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- The Emmes Company, LLC
Autism
Early Pharmacotherapy Aimed at Neuroplasticity in Autism : Safety and Efficacy
The purpose of this study is to determine the efficacy, safety, and population pharmacokinetics and determinants of drug responses to buspirone in children with autism using a randomized, double blind, cross over study in…
- Trial name
- NCT00166621
- Testing
- Buspirone
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Chugani, Diane C.
Infant, Premature, Diseases, Brain White Matter Disease Periventricular
Initial Efficacy Study of Supporting Play, Exploration, & Early Development Intervention
The primary aims of this randomized controlled trial are to evaluate efficacy potential of SPEEDI at enhancing reaching and play based problem solving compared to infants receiving usual care.
- Trial name
- SPEEDI (NCT02153736)
- Testing
- SPEEDI Intervention
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Virginia Commonwealth University
Autism Spectrum Disorder
Effects of Hippotherapy in Children With Autism Spectrum Disorder
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by difficulties in social communication and interaction, as well as impairments in physical function domains such as postural control, balance…
- Trial name
- NCT07739693
- Testing
- Hippotherapy Program, Special Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Fenerbahce University
Pectus Excavatum
Lung Ultrasound for the Postoperative Diagnosis of Pneumothorax in Children
This study will be conducted to determine the advantages and limitations of sonography compared with chest radiography, in the detection of post procedure iatrogenic pneumothorax in patients underwent to Pectus Excavatum (PE)…
- Trial name
- ECO_NUSS (NCT03073616)
- Testing
- Lung ultrasound
- Where
- Italy
- Volunteers
- 66 people
- Sponsor
- Nicola Disma, MD
Autism Spectrum Disorder
Evaluating BOSCC and ELSA as Outcome Measures in the Context of a JASPER Intervention Trial
Research teams in Boston University, UCLA, and Weill Cornell will recruit 90 participants in 3 years (10 participants per site per year) and evaluate JASPER, play-based intervention, using the BOSCC and ELSA-T.
- Trial name
- EBJ (NCT04146428)
- Testing
- clinician-mediated JASPER, parent-mediated JASPER
- Where
- 4 sites in United States
- Volunteers
- 84 people
- Sponsor
- University of California, Los Angeles
Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder
Evaluation of the Efficacy of Hippotherapy for Children With Developmental Disorders
Hippotherapy is every program of horseback riding meant to treat people with physiological, mental, social, cognitive or behavioral problems.
- Trial name
- NCT00717392
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Sheba Medical Center
Developmental Coordination Disorder
Gait and Muscle Power Training for Children With Developmental Coordination Disorder
Objectives: To compare the effectiveness of RAS-MPT, RAS alone, MPT alone, and usual care (as a control) for improving the overall gait performance of and reducing falls in children with developmental coordination disorder (DCD)…
- Trial name
- NCT03838614
- Testing
- Rhythmical auditory stimulation gait training and muscle power training (RAS-MPT), Rhythmical auditory stimulation gait training (RAS), Muscle power training (MPT)
- Where
- Hong Kong
- Volunteers
- 76 people
- Sponsor
- The University of Hong Kong
Obesity, Childhood
Development of an Eating Behavior Risk Score
This study will explore how children's eating behaviors are connected to brain activity and body fat levels. Researchers are especially interested in a behavior pattern called the PACE phenotype, which includes how much children…
- Trial name
- PACE (NCT07266506)
- Testing
- Assessment of PACE Eating Phenotype and Related Behavioral and Neurobiological Measures
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Penn State University
Anxiety, Depression
Transdiagnostic Behavioral Therapy for Anxiety and Depression in Autistic Adolescents
This study tests the effectiveness of a transdiagnostic cognitive behavioral therapy for autistic youth with anxiety and/or depression.
- Conditions
- Anxiety, Depression, Emotional Disorder, Autism
- Trial name
- NCT05738967
- Testing
- Transdiagnostic cognitive behavioral therapy (CBT), Treatment as usual
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Baylor College of Medicine
Pervasive Developmental Disorders
Social Skills in Children With Autism Spectrum Disorders
To evaluate whether a structured social skills program, called Social Skills Development,is superior to a wait list control group on measures of interpersonal interaction.
- Trial name
- SSD_ASD (NCT02147236)
- Testing
- Social Skills Training
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Yale University
Autism Spectrum Disorder
Hyperthermia and the Amelioration of Autism Symptoms
The febrile hypothesis of Autism Spectrum Disorder (ASD) stems from the observation that clinical symptoms improve during fever.
- Trial name
- NCT01784744
- Testing
- Hydroworx Pool at 98 degrees Fahrenheit, Hydroworx Pool at 102 degrees Fahrenheit
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Montefiore Medical Center
Autism Spectrum Disorder
Effectiveness of a 6-week Hippotherapy Program in Children With Autism Spectrum Disorder
The prevalence of autism spectrum disorders (ASD) has increased dramatically in the last decade. The increasing occurrence of ASD creates an imperative need to test the effectiveness and efficacy mechanisms of appropriate…
- Trial name
- NCT04772898
- Testing
- Hippotherapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Creighton University
Leukemia, Myelodysplastic Syndromes
Combination Chemotherapy With or Without Filgrastim and/or Tretinoin in Treating Patients With Acute Myeloid Leukemia
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Colony-stimulating factors such as filgrastim may increase the number of immune cells found in bone marrow…
- Conditions
- Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms
- Trial name
- NCT00005863
- Testing
- filgrastim, cytarabine, daunorubicin hydrochloride
- Where
- United Kingdom
- Sponsor
- Medical Research Council
Turner Syndrome, Infertility, Female
Turner Syndrome Minipuberty Study
Rationale: Due to accelerated germ cell loss, infertility is a major problem in girls with Turner syndrome (TS). Therefore, cryopreservation of ovarian tissue or oocytes before exhaustion of the ovarian reserve may preserve…
- Conditions
- Turner Syndrome, Infertility, Female, Premature Ovarian Failure, Gonadal Dysgenesis
- Trial name
- Minipuberty (NCT04189406)
- Testing
- Venapunction
- Where
- 13 sites in Denmark, Germany and 3 more
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Hearing Loss
Bilateral Cochlear Implant Benefit in Young Children
The primary purpose of this study is to track patient outcomes for bilateral cochlear implant recipients in a cohort of 60 children, ages 12 to 36 months at time of surgery, who receive two implants in the same operation or in…
- Trial name
- NCT00424307
- Testing
- HiResolution Bionic Ear System
- Where
- 14 sites in United States, Canada
- Volunteers
- 60 people
- Sponsor
- Advanced Bionics
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