Clinical trials: Developmental Disorder
Hip Developmental Dysplasia
Effect of Cross-legged Sitting Among Patients With Unilateral Hip Developmental Dysplasia
One of the most common infant developmental diseases is Hip dysplasia which is mostly seen among female' babies and leads to hip instability due to partial or full hip dislocation [1].
- Trial name
- NCT07002840
- Testing
- Cross- legged sitting position, Physical Therapy Rehabilitation Program
- Volunteers
- 16 people
- Sponsor
- Jouf University
the Safety of Anti-viral Drugs Used in Late Pregnancy
The Effect of Anti-viral Drugs Used in Late Pregnancy on Long-term Development of Children
Mother to child transmission(MTCT) is the main route of hepatitis B virus(HBV) transmission.High HBV DNA level of pregnant women is the main risk factor of MTCT.
- Trial name
- NCT02301650
- Testing
- Lamivudine, Telbivudine, Tenofovir
- Volunteers
- 400 people
- Sponsor
- Beijing Ditan Hospital
Pulmonary Hypertension, Lung Disease
Hospital-Based Program for Treatment of Severe Cardiopulmonary Disease With Inhaled Nitric Oxide
The purpose of this program is to evaluate the logistic issues and patient requirements for chronic pulsed INOmax delivery in ambulatory, home-care patients.
- Conditions
- Pulmonary Hypertension, Lung Disease, Sickle Cell Disease, Cardiac Transplant
- Trial name
- NCT00041574
- Testing
- Inhaled Nitric Oxide
- Where
- 3 sites in United States
- Volunteers
- 7 people
- Sponsor
- Mallinckrodt
Child Development, Mother-Infant Interaction
Clinical Interventions to Mitigate Neurodevelopmental Risk
Family Nurture Intervention (FNI) has been shown to facilitate emotional connection and long-term child developmental progress in the NICU population.
- Conditions
- Child Development, Mother-Infant Interaction, Diabetes Mellitus, Gestational
- Trial name
- NCT04233489
- Testing
- Family Nurture Intervention (FNI)
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Columbia University
Postnatal Growth Disorder
Physiologic Approach to Sodium Supplementation in Premature Infants
Postnatal growth failure occurs in up to 50% of very low birth weight (VLBW, <1500 grams at birth) infants as assessed by discharge weight.
- Trial name
- Salt to Grow (NCT03889197)
- Testing
- Sodium supplementation guided by urine sodium concentration algorithm
- Where
- 3 sites in United States
- Volunteers
- 90 people
- Sponsor
- Indiana University
Autism Spectrum Disorder, Executive Dysfunction
Non-invasive Brain Stimulation in Children With Autism
Although many children diagnosed with autism spectrum disorder (ASD) make significant progress in learning and their cognitive skills improve with applied behavior analysis (ABA), there are a significant number of children who…
- Conditions
- Autism Spectrum Disorder, Executive Dysfunction, Child Autism
- Trial name
- NCT05105126
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Sponsor
- Rutgers, The State University of New Jersey
Obesity Associated With Defects in Leptin-melanocortin Pathway
Open-Label Extension Study of Setmelanotide
This is an open-label extension study designed to evaluate the long-term safety and tolerability of continued setmelanotide treatment in male and female patients ≥2 years of age who have completed or transitioned from a previous…
- Trial name
- NCT06596135
- Testing
- Setmelanotide
- Where
- 13 sites in United States
- Volunteers
- 28 people
- Sponsor
- Rhythm Pharmaceuticals, Inc.
Amelogenesis Imperfecta, Dental Fluoroses
Colorimetric, Ultra-structural and Elemental Comparison of Dental Enamel Defects
The study focuses on the analysis of enamel defects grouping together hypomineralization and hypoplasia. It focuses on 3 very characteristic enamel pathologies that are most often encountered in dental consultations: Molar…
- Conditions
- Amelogenesis Imperfecta, Dental Fluoroses, Hypomineralization Molar Incisor
- Trial name
- COLOEMAIL (NCT04704089)
- Testing
- spectrophotometer, Biological (protein analysis by western blot or mass spectrometry of matrix proteins), structural (electron microscopy) and physico-chemical analyses
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism Spectrum Disorder, Autism
A Proof-of-Concept Study of Minocycline in Autism
The purpose of the study is to determine if Minocycline shows initial evidence of efficacy, safety, and tolerability in youth with Autism Spectrum Disorder ages 12 to 22 years.
- Trial name
- NCT04031755
- Testing
- Minocycline
- Where
- 3 sites in United States
- Volunteers
- 53 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autism Spectrum Disorder, Child
AI Toothbrush and Visual Pedagogy to Improve Oral Hygiene in Children With Autism Spectrum Disorder
This randomized clinical trial evaluates the effectiveness of an AI-enabled electric toothbrush and visual pedagogy materials in improving oral hygiene among children with autism spectrum disorder (ASD).
- Conditions
- Autism Spectrum Disorder, Child, Oral Health, Artificial Intelligence
- Trial name
- NCT07160517
- Testing
- Visual Pedagogy and Manual Toothbrushing
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Diarrhea, Malnutrition
Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development
Malnutrition is considered one of the most prevalent risk factors for morbidity and mortality in children under five. An estimated 20% of children in the developing world are malnourished [1] and poor nutrition is linked to more…
- Conditions
- Diarrhea, Malnutrition, Stunting, Wasting
- Trial name
- MAL-ED (NCT02441426)
- Where
- 8 sites in Bangladesh, Brazil and 6 more
- Volunteers
- 1,796 people, healthy volunteers welcome
- Sponsor
- Foundation for the National Institutes of Health
Autism Spectrum Disorder
Vitamin/Mineral Supplement for Children With Autism
This is an open-label 3 month clinical trial of a vitamin/mineral supplement designed for children with autism.
- Trial name
- NCT04845776
- Testing
- ANRC Essentials Plus
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Arizona State University
ADHD
Neurofeedback Intervention on the Development of ADHD in Children at Risk
Forty children considered at risk for ADHD (subclinical ADHD) will be randomized to either a neurofeedback intervention or waiting list.
- Trial name
- NCT01692548
- Testing
- Neurofeedback
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Autism Spectrum Disorder, Autism
Effectiveness of a Developmental Reciprocity Treatment Program in Autism
This is a research study examining the effectiveness of a Developmental Reciprocity Treatment Program (DRT-P) in treating social deficits in children with Autism Spectrum Disorders (ASD).
- Trial name
- DRTP (NCT03131635)
- Testing
- Developmental Reciprocity Treatment Program (DRT-P)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Stanford University
Tuberous Sclerosis Complex
Clinical Study of NPC-12Y Gel in Patients With Skin Lesions Associated With TSC
The purpose of this study is to investigate the efficacy and safety of NPC-12Y gel compared with placebo for skin lesions associated with tuberous sclerosis.
- Trial name
- NCT05495425
- Testing
- NPC-12Y gel
- Where
- 5 sites in Japan
- Volunteers
- 43 people
- Sponsor
- Nobelpharma
Acute Graft-versus-host Disease
Effect of Stem Cell Infusion Time on aGVHD in Patients With Hematological Malignancies
To observe the effect of stem cell infusion on the development of acute graft-versus-host disease (aGVHD) in patients with malignant hematologic diseases after allogeneic peripheral blood hematopoietic stem cell transplantation…
- Trial name
- NCT06294678
- Testing
- Time of stem cell infusion
- Where
- 6 sites in China
- Volunteers
- 198 people
- Sponsor
- Anhui Provincial Hospital
Preterm Infant, Full-term Infant
A Novel Parent Education Program for Early Intervention
One in ten infants born in the USA is born preterm before 37 weeks of gestation and 50% of those will have motor and cognitive delays requiring intervention at school age.
- Trial name
- NCT04266717
- Testing
- Baby Play Intervention, Milestone Education
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Exostoses, Multiple Hereditary
The Health-Related Quality of Life in Patients With Hereditary Multiple Exostoses
The purpose of this study is to assess the health-related quality of life of subjects who have Hereditary Multiple Exostoses and to develop a disease specific quality of life survey.
- Trial name
- NCT00474448
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Pectus Excavatum, Pectus Excavatum Deformity
The Effects of Schroth Based Exercise Therapy in Adolescents with Pectus Excavatum
Research on exercise methods for pectus excavatum (PE) is limited, highlighting the need for further studies. This study investigated the effects of Schroth-based exercise therapy combined with vacuum treatment in 35 adolescents…
- Conditions
- Pectus Excavatum, Pectus Excavatum Deformity, Funnel Chest, Chest Deformities
- Trial name
- NCT06763406
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Hacettepe University
Congenital Hypothyroidism
Clinical and Genetic Analysis in Congenital Hypothyroidism Due to Thyroid Dysgenesis.
Congenital hypothyroidism (CH) is a rare disease that affects 1 in 3500 newborn. This condition is detected consistently since the late 1970s in France, which has led to early care and a significant improvement in prognosis and…
- Trial name
- HYPOTYGEN (NCT01916018)
- Testing
- Clinical and radiologic exams and blood samples
- Where
- France
- Volunteers
- 558 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.