Clinical trials: Developmental Disorder
Autism Spectrum Disorder
An Exploratory Open Label Study of EPI-743 (Vincerinone TM) in Children With Autism Spectrum Disorder
The investigators hypothesize that EPI-743 may provide clinical benefit to children with Autism Spectrum Disorder.
- Trial name
- Autism (NCT02226458)
- Testing
- EPI-743
- Sponsor
- Edison Pharmaceuticals Inc
Pectus Excavatum, Funnel Chest
Cryoanalgesia vs. Epidural in the Nuss Procedure
The purpose of this study is to determine whether cryoanalgesia provides better pain control for minimally invasive pectus excavatum repair (the Nuss procedure) than thoracic epidural.
- Trial name
- NCT02721017
- Testing
- Cryoanalgesia, Thoracic epidural (ropivicaine, fentanyl)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Cerebral Palsy
Rhythm and Multisensoriality's Effects on the Motor Development in Children With Cerebral Palsy
Cerebral palsy (CP) affects the motor function but also the cognitive function of the child. Physical activity brings motor and cognitive benefits and appears as an important aspect of the therapy that is offered to them.
- Trial name
- APP-PaC (NCT03440749)
- Testing
- luminous stimuli
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Glucose Transporter Type 1 Deficiency Syndrome, GLUT1 Deficiency Syndrome
Treatment Development for Glucose Transporter Type I Deficiency Syndrome (G1D)
The purpose of this trial is to determine if an alternative energy source will impact brain metabolism in a disorder characterized by glucose metabolism failure in the brain.
- Trial name
- NCT02018315
- Testing
- Triheptanoin
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Juan Pascual
Autism Spectrum Disorder, Executive Function
The Effect of Cognitive Orientation Approach on Daily Occupational Performance With Autism Spectrum Disorder
The goal of this clinical trial is by using the Cognitive Orientation Approach on Daily Occupational Performance, which is also supported by the literature and applied by occupational therapists, in children diagnosed with Autism…
- Conditions
- Autism Spectrum Disorder, Executive Function, Patient Participation
- Trial name
- NCT06038435
- Testing
- Cognitive Orientation Approach, Ayres Sensory Integration Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Bezmialem Vakif University
Vitamin D Deficiency, Body Composition
GraviD-child Follow-up of the Children´s Health, Growth and Development Within the GraviD-study
GraviD is a multi-ethnic population-based pregnancy cohort. Pregnant women were invited to participate in the GraviD study when registering for antenatal care in parts of the region of Västra Götaland in Sweden in 2013-2014.
- Conditions
- Vitamin D Deficiency, Body Composition, Vascular Health, Cardiometabolic Risk
- Trial name
- NCT05228925
- Testing
- Maternal vitamin D status
- Where
- Sweden
- Volunteers
- 172 people
- Sponsor
- Göteborg University
Rett Syndrome, RTT
Neurophysiologic Biomarkers in Rett Syndrome
The goal of this observational study is to identify candidate biomarkers in individuals with Rett Syndrome (RTT). The main questions it aims to answer are: Do these biomarkers change during clinical changes in individuals with…
- Conditions
- Rett Syndrome, RTT, Rett Syndrome, Atypical
- Trial name
- NCT05932589
- Testing
- EEG and Auditory and Visual Evoked Potentials (AEP and VEP), Clinical assessment
- Where
- 6 sites in United States
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Myopia
Ambient Light Levels in the Kindergarten and Schools and the Relation to Refractive Development
Myopia, the most common human eye disorder, is a phenomenon characterized by an unconstrained elongation of the eye globe There are number of theories concerning the environmental effect on the emmetropization process, most are…
- Trial name
- NCT02854891
- Testing
- autorefractometer, A-scan ultrasound
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Mental Health Issue, Externalizing Behavior Problems
3D-Transition: Challenges and Resources of Children and Their Families During the Transition From Preschool to School
The 3D-Transition study is a follow-up of the 3D Cohort pregnancy study (NCT03113331, which covered from the 1st trimester of pregnancy to age 2 years) as the children transition into kindergarten and first grade.
- Conditions
- Mental Health Issue, Externalizing Behavior Problems, Internalizing Behavior Problems, Cognitive Development
- Trial name
- NCT04873518
- Where
- 3 sites in Canada
- Volunteers
- 939 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Severe Acute Malnutrition in Childhood
Severe Acute Malnutrition and Child Development Clinical Trial in Mwanza
This is a randomized clinical trial to learn whether ready-to-use therapeutic foods enriched with choline and docosahexaenoic acid (DHA) together with psychosocial stimulating activities work well to improve child development in…
- Trial name
- BRIGHTSAM (NCT06781918)
- Testing
- Ready to Use Therapeutic Food (RUTF), Psychosocial stimulation
- Where
- Tanzania
- Volunteers
- 800 people
- Sponsor
- National Institute for Medical Research, Tanzania
Cerebral Palsy
Development of a Remote Therapy Protocol for Upper Limb Function Enhancement in Children With Cerebral Palsy
The perpose of this study: Development and demonstration of a teletherapy protocol to improve upper limb function in children with cerebral palsy.
- Trial name
- NCT06272760
- Testing
- Home-based hand-arm bimanual intensive training (Tele-HABIT)
- Where
- South Korea
- Volunteers
- 29 people
- Sponsor
- Samsung Medical Center
Autism, Autism Spectrum Disorder
Work Chat: An Interactive Virtual Workday
Nearly 50,000 youth with autism spectrum disorder (ASD) transition from high school to adult life each year with only 25% of these transition-age youth with ASD (TAY-ASD) getting jobs within 2 years of graduation.
- Trial name
- NCT05565482
- Testing
- Work Chat: An Interactive Virtual Workday
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Michigan
Asthma
Airway Inflammation in Swimmers
Studies have shown that the prevalence of respiratory symptoms, airway hyperresponsiveness (AHR) and asthma is high and increasing in elite athletes.
- Trial name
- NCT00207038
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Pectus Excavatum, Pectus Carinatum
Psychological Assessment of Patients With Chest Wall Deformities
The study aims to investigate the most frequent psychological outcomes associated to chest wall deformities and patients' quality of life.
- Trial name
- NCT04362878
- Where
- Italy
- Volunteers
- 209 people
- Sponsor
- University of Florence
Post-Traumatic Stress Disorder
Posttraumatic Symptoms Among Toddlers and Their Parents Following Exposure to Terrorism
The project utilize experience and knowledge gained from previous early childhood projects in NYC post 9/11 and Sderot. The overall goals are: 1.
- Trial name
- NCT00447538
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Herzog Hospital
Childhood Obesity
Effect of Dietary Fat Cooking Blend on Energy Expenditure in Children
The purpose of this study is to test the effects of a cooking oil blend of dietary fats rich in medium chain triglycerides on energy expenditure and food intake in overweight and obese children.
- Trial name
- Melt (NCT01720589)
- Testing
- Melt (test oil), Corn oil (control)
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Vision, Low, Child
CREATE - Children Reading With Electronic Assistance To Educate
This pilot randomized controlled trial (RCT) will test the methodology for a full RCT of assistive technologies for children/young people with low vision/blindness.
- Conditions
- Vision, Low, Child, Adolescent Development
- Trial name
- CREATE (NCT02798848)
- Testing
- Tablet computer
- Where
- 3 sites in India, United Kingdom
- Volunteers
- 40 people
- Sponsor
- University College, London
Cerebral Palsy, Autism
Rehabilitation of Children With Multiple Disabilities
The objective of the study is to compare the usual care and treatment of children and youth (0-19 years) with multiple developmental delays and disabilities and their families in Simcoe York with a co-ordinated, navigated…
- Conditions
- Cerebral Palsy, Autism, Down's Syndrome, Brain Injury
- Trial name
- NCT01379443
- Testing
- CTN model of care for children and their families
- Where
- Canada
- Volunteers
- 445 people
- Sponsor
- Children's Treatment Network
Autism Spectrum Disorder
Online Parent-Mediated Intervention for Preschool Autistic Children
Autism spectrum disorder (ASD) is characterized by persistent deficits in social communication and interaction, accompanied by restricted and repetitive patterns of behavior.
- Trial name
- OYNA-1 (NCT07742774)
- Testing
- OYNA-1: Online Group-Based Parent-Mediated Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people
- Sponsor
- Herguner Therapy Private Clinic
Breast Cancer, HER2-negative Breast Cancer
Post-Marketing Surveillance Study of Eribulin on the Status and Factors for the Development of Peripheral Neuropathy in Japan.
The primary objective of the study is to clarify factors affecting the incidence of peripheral neuropathy in patients treated with HALAVEN.
- Trial name
- NCT02371174
- Where
- 2 sites in Japan
- Volunteers
- 651 people
- Sponsor
- Eisai Co., Ltd.
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