Clinical trials: Developmental Disorder
Autism Spectrum Disorder
A Study of Mesenchymal Stem Cell in the Treatment of Autism Spectrum Disorder
This clinical trial aims to evaluate the safety and preliminary efficacy of intravenous administration of human bone marrow-derived mesenchymal stem cells (hBMMSCs) in patients with autism spectrum disorder (ASD).
- Trial name
- ASD (NCT07177677)
- Testing
- hBMMSC
- Volunteers
- 42 people
- Sponsor
- Jiuzhitang Maker (Beijing) Cell Technology Co.,Ltd.
Tuberous Sclerosis, Subependymal Giant Cell Astrocytoma
Everolimus (RAD001) Therapy of Giant Cell Astrocytoma in Patients With Tuberous Sclerosis Complex
The purpose of the study is to evaluate the safety and potential side effects of everolimus (an experimental drug) on a person with Tuberous Sclerosis Complex who also has been diagnosed with a brain tumor (astrocytoma) The…
- Trial name
- NCT00411619
- Testing
- Everolimus
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autism Spectrum Disorders, Schizophrenia
Visual Exploration and Attention: Studies in Patients With Schizophrenia and Autism Spectrum Disorders
The aim of the protocol is to better understand the impairments in visual processing, as such impairments may induce social interaction difficulties in subjects with autism spectrum disorders (adults and children) and…
- Trial name
- NCT00914030
- Testing
- Neuropsychological evaluation
- Where
- 5 sites in France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Cystic Fibrosis
LC-MS/MS Based Method Development for the Monitoring of Antibiotic Concentrations in Sputum of Cystic Fibrosis Patients
In this trial, various factors that may influence the antibiotic concentrations measured in the sputum of cystic fibrosis patients are studied. A first factor is aerosol use.
- Trial name
- NCT02840136
- Testing
- Piperacillin-tazobactam combination product, Meropenem, Ceftazidime
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- University Ghent
Depression, Anxiety
Development of a College Student-Delivered Cognitive-Behavioral Therapy (CBT) Intervention for Rural High School Students
This research is being done to find out the effectiveness, feasibility, and acceptability of a college student-delivered cognitive-behavioral therapy (CBT) intervention in high schools in rural Schuylkill County, Pennsylvania to…
- Conditions
- Depression, Anxiety, Stress
- Trial name
- NCT07240792
- Testing
- Student Delivered Cognitive Behavioral Therapy Intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Milton S. Hershey Medical Center
Epilepsy
Development and Clinical Application of [11C]Verapamil-PET
The major hypothesis explaining drug resistance is overexpression of p-glycoprotein at the target lesion. Based on several studies, p-glycoprotein (P-gp) has an important role in neurologic diseases, especially in drug resistant…
- Trial name
- NCT02144792
- Testing
- [11C] -verapamil PET
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Motor Disorders
Artificial Intelligence for Infant Motor Screening: Development and Validation
The purpose of this three-year study is therefore three-fold: (1) Model Development- to apply pose estimation model and tracking recognition model on the movements of a large sample of term and preterm infants under a motor…
- Trial name
- NCT05456126
- Where
- Taiwan
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder
Pimavanserin for Rigid-compulsive Symptoms in Autism Spectrum Disorder
This Phase 2 study examines the safety, tolerability, and preliminary efficacy of pimavanserin in individuals with Autism Spectrum Disorder.
- Trial name
- NCT05999240
- Testing
- Pimavanserin Tartrate 34 Mg ORAL CAPSULE [NUPLAZID]
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- New York State Psychiatric Institute
Asphyxia Neonatorum
Asphyxia Associated Metabolite Biomarker Investigation (AAMBI)
Verification of biomarkers in a human population for their ability to diagnose the severity of neonatal asphyxia. These biomarkers linked to asphyxia have been identified in animal studies.
- Trial name
- AAMBI (NCT03354208)
- Testing
- blood sampling
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Life Science Inkubator
Leukemia, Myelodysplastic Syndromes
Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells.
- Trial name
- NCT00002517
- Testing
- cytarabine, daunorubicin hydrochloride, dexamethasone
- Where
- 23 sites in Belgium, France and 1 more
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Hypospadias
Molecular and Structural Comparison of Hypospadic and Normal Children Prepuces
The aim of this study is to compare prepuce tissue samples from healthy male children who applied for circumcision and children with isolated hypospadias.
- Trial name
- NCT03838458
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Trakya University
Allergic Rhinitis (Disorder)
The Development of Allergic Rhinitis in Children Previously Diagnosed as Nonallergic Rhinitis
The purpose of this study is to evaluate development of allergic rhinitis in children with nonallergic rhinitis.
- Trial name
- NCT01068808
- Testing
- skin prick test
- Where
- Thailand
- Volunteers
- 175 people
- Sponsor
- Mahidol University
Malnutrition, Manihot Species Poisoning
Caregiver Training to Prevent Konzo Disease in Children in Democratic Republic of Congo (DRC)
The proposed research adapted the caregiver training and child neurodevelopmental assessment capacity that the PI previously built in Uganda beginning in 2008, to a community-based intervention model for the prevention of konzo…
- Trial name
- NCT04036708
- Testing
- Wetting method (WTM), Mediational Intervention for Sensitizing Caregivers (MISC)
- Where
- Democratic Republic of the Congo
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Preterm Birth
Adolescents Born Preterm; Nurtured Beginnings
This research study is a long-term follow-up to an earlier study of developmental care. For that study, high risk preterm newborns were randomly assigned to a standard care group, which received the standard care offered in the…
- Trial name
- NCT00310869
- Testing
- Individualized Developmental Care in the NICU
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Boston Children's Hospital
Connective Tissue Disease, Dissecting Aneurysm
Study of Heritable Connective Tissue Disorders
The purposes of this study are to identify the genes responsible for inherited connective tissue disorders and learn about the range of medical problems they cause.
- Conditions
- Connective Tissue Disease, Dissecting Aneurysm, Ehlers Danlos Syndrome, Marfan Syndrome
- Trial name
- NCT00001641
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Arrhythmia in Children
Electrocardiography for the Automatic Analysis of Arrhythmia in Children
The project is a direct response to the identified lack of ECG diagnostic solutions dedicated to children. There are several tools for automatic ECG signal analysis in adults, but these cannot be used in the diagnosis of heart…
- Trial name
- NCT05272722
- Testing
- ECG,
- Where
- Poland
- Volunteers
- 675 people
- Sponsor
- Medical University of Warsaw
Premature Baby 26 to 32 Weeks, Bronchopulmonary Dysplasia
Respiratory Outcome at Adolescence of Very Low Birthweight Infants
EPIPAGEADO is an observational study. Respiratory symptoms and lung function will be evaluated in very low birth weight and term infants, born in 1997 and included in the French EPIPAGE cohort.
- Trial name
- EPIPAGEADO (NCT01424553)
- Testing
- Prevention and follow-up of the patients pulmonary parameters
- Where
- France
- Volunteers
- 355 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism Spectrum Disorder
Ayres Sensory Integration in Preschool Children With Autism Spectrum Disorder
This study evaluates the effectiveness of occupational therapy using Ayres Sensory Integration® (ASI) in preschool children with autism spectrum disorder (ASD).
- Trial name
- NCT07507630
- Testing
- Ayres Sensory Integration, Usual Care
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Medipol University
Attention Deficit Hyperactivity Disorder (ADHD), Autism
The TEAM Study - Treatment Efficacy for Autism/Attention Using Mixed Amphetamine
The investigators are conducting a 10-week brain imaging and medication study. They are doing the research to study the response of Attention-Deficit/ Hyperactivity Disorder (ADHD) in youth with Autism Spectrum Disorder (ASD) on…
- Conditions
- Attention Deficit Hyperactivity Disorder (ADHD), Autism, Autism Spectrum Disorder
- Trial name
- NCT06853665
- Testing
- Adderall XR (mixed salts amphetamine)
- Where
- United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Gagan Joshi
Visual Impairment, Cerebral Visual Impairment
Body Image, Identity Development, and Social Media Use Among Youth With Visual Impairment: A Single Case Intervention Study
1. Introduction This 3-week single case intervention study is funded by the Horizon Europe Research Program and is part of the VIPPSTAR project (Project 101156763 - VIPPSTAR "Visually Impaired children and adolescents: bridging…
- Conditions
- Visual Impairment, Cerebral Visual Impairment, Visual Impairments
- Trial name
- VIPPSTAR_G3KUL (NCT07741500)
- Testing
- Body image intervention
- Where
- 2 sites in Belgium
- Volunteers
- 15 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
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