Clinical trials: Developmental Disorder
Deafness, Hearing Loss
Benefits of Tablet-based Serious Games to Promote Speech Production in Young Children With Hearing Disabilities
Learning to speak is a major challenge for children with hearing impairments. Nowadays, special devices such as conventional hearing aids, bone-anchored hearing aids (BAHA) or cochlear implants (CI) allow successful…
- Trial name
- FunSpeech (NCT04454255)
- Testing
- FunSpeech, Control
- Where
- Switzerland
- Volunteers
- 13 people
- Sponsor
- University Hospital, Geneva
Edema, Chronic Venous Insufficiency
Validation of a New Method of Limb Volumetry
Volumetry is essential for the diagnosis and follow-up of patients with limb edema. The objective of this project is the validation of real-time reconstruction and calculation of limb volume using a 3D laser scanner.
- Conditions
- Edema, Chronic Venous Insufficiency, Lymphedema
- Trial name
- NCT01574911
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Autistic Disorder
Characterisation of Circadian Rhythm in Autistic Spectrum Disorder
Autism spectrum disorders (ASDs) are complex neurodevelopmental conditions characterized by deficits in social communication, delay in language and repetitive behaviors.
- Trial name
- NCT01984944
- Testing
- Autistic functional exploration, Control functional exploration
- Where
- France
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hypospadias
Molecular and Structural Comparison of Hypospadic and Normal Children Prepuces
The aim of this study is to compare prepuce tissue samples from healthy male children who applied for circumcision and children with isolated hypospadias.
- Trial name
- NCT03838458
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Trakya University
Orthognathic Surgery, Dentofacial Deformities
Development and Validation of an Automated Three-dimensional Cephalometry Method
This study is aimed to develop and assess the validity of an algorithm for automated three-dimensional cephalometry.
- Trial name
- AutoCEPH-3D (NCT04464252)
- Where
- France
- Volunteers
- 453 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Craniosynostoses
EPBONF : Evaluation of the Safety and Effectiveness of a Medical Device Aimed at Guiding Orbito-naso-frontal Band Surgery, for the Treatment of Craniostenoses
Craniostenosis is a congenital disorder caused by early fusion of the cranial sutures between the skull bones, resulting in orbito-naso-frontal deformities.
- Trial name
- EPBONF (NCT06366178)
- Testing
- BONFIX system
- Volunteers
- 5 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Growth Hormone Deficiency
National Cooperative Growth Study in CKD
The purpose of this study is to learn whether growth hormone being administered to children with Chronic Kidney Disease is effective and if it has any side effects.
- Trial name
- NCGS (NCT00616278)
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of California, Davis
Brain Injuries, Brain Development Abnormality
Evaluating the Efficacy of SyMRI in Clinical Pediatric Populations
Synthetic MR Technologies has created a quantified imaging solution - SyMRI - to enable radiologists to acquire quantified images and always obtain the best contrast images.
- Conditions
- Brain Injuries, Brain Development Abnormality, Brain Pathology
- Trial name
- SyMRI (NCT03494855)
- Testing
- SyMRI Software
- Where
- Canada
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Neoplasms Pancreatic
PRIMUS002: Looking at 2 Neo-adjuvant Treatment Regimens for Resectable and Borderline Resectable Pancreatic Cancer
PRIMUS 002 is looking at 2 different chemotherapy regimens in the neo-adjuvant setting for pancreatic cancer. Each treatment will be given for 3 months prior to surgery
- Trial name
- PRIMUS002 (NCT04176952)
- Testing
- FOLFOX-A, AG
- Where
- 3 sites in United Kingdom
- Volunteers
- 31 people
- Sponsor
- Judith Dixon-Hughes
Autism Spectrum Disorder
Effectiveness of the Care Coordination, Assessment, and Responsive Engagement Program for Transition-aged Adolescents (t-CARE) With ASD
An analysis of data for adolescents and young adults diagnosed with Autism Spectrum Disorders (ASDs) who are evaluated as part of the Care Coordination, Assessment, and Responsive Engagement for transition-aged adolescents…
- Trial name
- t-CARE (NCT03019952)
- Testing
- Care Coordination Visit
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Growth Disorders
Treatment of Children and Adolescents With Growth Failure Associated With Primary IGF-1 Deficiency
This is an extension study to Tercica study MS301 (NCT00125164) and is intended to collect long term safety and efficacy data on the continued use of recombinant human insulin-like growth factor-1 (rh IGF-1) in children and…
- Trial name
- NCT00330668
- Testing
- rh IGF-1 (mecasermin)
- Where
- France
- Volunteers
- 114 people
- Sponsor
- Ipsen
SCHIZOPHRENIA 1 (Disorder)
Multi-target TMS for Schizophrenia Negative Symptoms
This randomized controlled trial (RCT) is the first to evaluate the efficacy and safety of a multi-target TMS protocol targeting the right orbitofrontal cortex (R-OFC), left dorsolateral prefrontal cortex (L-DLPFC), and left…
- Trial name
- NCT07559084
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Shanghai Mental Health Center
Attention Deficit Disorder With Hyperactivity, Developmental Coordination Disorder
Co Morbid Attention Deficit and Hyperactivity Disorder(ADHD) and Developmental Co Ordination Disorder (DCD)
This study aims to establish and present the prevalence figures and demographics of the co-morbidity of ADHD and DCD. It further aims to design an exercise intervention, to be utilised in the management of the symptoms of both…
- Trial name
- NCT03595826
- Testing
- Neurostimulant pharmaceutical drugs
- Where
- South Africa
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- University of KwaZulu
Pompe Disease, Glycogen Storage Disease Type II (GSD-II)
Growth and Development Study of Alglucosidase Alfa
Pompe disease (also known as glycogen storage disease Type II) is a rare autosomal recessive metabolic muscle disease caused by the deficiency of acid α glucosidase (GAA), an enzyme that degrades lysosomal glycogen.
- Conditions
- Pompe Disease, Glycogen Storage Disease Type II (GSD-II), Acid Maltase Deficiency Disease
- Trial name
- NCT00486889
- Testing
- alglucosidase alfa
- Where
- 3 sites in United States
- Volunteers
- 12 people
- Sponsor
- Genzyme, a Sanofi Company
Funnel Chest
Evaluation of Chest Wall Motility After MIRPE
Pectus excavatum (PE) is the most common congenital deformity of the chest wall and surgical treatment using the minimally invasive technique (MIRPE) is consolidating as the choice to perform PE correction.
- Trial name
- NCT05124626
- Testing
- MIRPE with two bars, MIRPE with one bar
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Mental Retardation, Developmental Delay Disorder
Atypical Neuroleptic Drugs in People With Mental Retardation/Developmental Delay
Psychiatric drugs are often used to treat behavioral symptoms of mental retardation/developmental delay (MR/DD). These drugs can cause serious side effects. Newer drugs may have decreased side effects.
- Trial name
- NCT00065273
- Testing
- risperidone, clozapine, olanzapine
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Anxiety Disorders in Youth With Autism, Asperger's Syndrome, and Pervasive Developmental Disorder Not Otherwise Specified
Cognitive Behavioral Therapy (CBT) for Anxiety Disorders in Autism: Adapting Treatment for Adolescents
Comorbid anxiety disorders affect as many as 80% of youth with autism spectrum disorders, causing substantial distress and impairment over and above the autism spectrum diagnosis alone.
- Trial name
- NCT01177969
- Testing
- Cognitive-Behavioral Therapy, Wait-list
- Where
- 2 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Autism
Trial of Vitamin D3 Supplementation in Paediatric Autism
To build on a recent case study and open label trial, the investigators want to find out if vitamin D supplementation can influence behavioural and core symptoms of autism.
- Trial name
- NCT02508922
- Testing
- Vitamin D3
- Where
- 3 sites in Ireland
- Volunteers
- 42 people
- Sponsor
- University of Dublin, Trinity College
Autism Spectrum Disorder
The Westmead Feelings Program Intervention for Chinese Children With Autism Spectrum Disorder in Hong Kong
The goal of this intervention is to evaluate the effectiveness of delivering the Westmead Feelings Program 2 to children with Autism Spectrum Disorder in primary schools in Hong Kong.
- Trial name
- NCT06206070
- Testing
- The Hong Kong version of Westmead Feeling Program 2
- Where
- Hong Kong
- Volunteers
- 85 people
- Sponsor
- The University of Hong Kong
Stroke
Telerehabilitation for Attention and Memory in Stroke
The investigators propose to develop a Telerehabilitation approach to working memory training for patients experiencing working memory deficits post stroke.
- Trial name
- TEAMS (NCT02405351)
- Testing
- Adaptive Working Memory Training
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- Nova Scotia Health Authority
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