Clinical trials: Developmental Disorder
Patella, Joint Instability
Development of a Test Battery for Measurement of Knee Function in Patients With Patellar Instability
About six months after patella stabilizing surgery postoperative restrictions are commonly lifted and patients may consider whether a return to activity/sports is feasible.
- Conditions
- Patella, Joint Instability, Patellofemoral Joint Dislocation
- Trial name
- NCT05119088
- Testing
- Return to Sport testbattery
- Where
- Norway
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Haraldsplass Deaconess Hospital
Autism, Autism Spectrum Disorder
Online Evaluation of the Diagnostic Accuracy of BlinkLab's Digital Assessments for Autism
This observational study aims to evaluate how patterns of behavioral and sensorimotor responses measured using the BlinkLab Dx1 smartphone application relate to autism diagnoses in children ages 2 to 11.
- Conditions
- Autism, Autism Spectrum Disorder, Autism Spectrum Disorder (ASD), Neurodevelopmental Conditions
- Trial name
- NCT07590973
- Testing
- BlinkLab Dx1, Retrospective Neurodevelopmental Diagnostic Assessment
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Blinklab Limited
Autism Spectrum Disorder
STEPS: Stepped Transition in Education Program for Students With ASD
Young adults who have Autism Spectrum Disorder (ASD) without co-occurring intellectual impairment face a fairly unique set of challenges as they transition out of secondary school.
- Trial name
- STEPS (NCT02468505)
- Testing
- STEPS
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Virginia Polytechnic Institute and State University
Pediatric Obesity
Childhood Obesity, Lifestyle Interventions and Weight Development
Childhood obesity has been associated with increased risk of both continued excess body weight, development of non-communicable lifestyle diseases and impaired mental health.
- Trial name
- NCT05345353
- Testing
- Fat For Fight (FFF), The Aarhus Protocol, The Children's Obesity Clinic Treatment (TCOCT), The Randers Protocol
- Where
- Denmark
- Volunteers
- 2,898 people
- Sponsor
- University of Aarhus
Autism Spectrum Disorder, Intellectual Disability
TMS for the Investigation of Brain Plasticity in Autism Spectrum Disorders
The main purpose is to study brain plasticity (the changes that occur in the brain through experience) in individuals with autism spectrum disorder (ASD).
- Trial name
- NCT02836405
- Testing
- Transcranial Magnetic Stimulation
- Where
- 2 sites in United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Learning Disorders
Risk and Resilience Factors in Learning Disabilities Population
The purpose of this study is to report preliminary outcomes of executive function and psychopathology symptoms of a manual-based psychological intervention for adolescents diagnosed with learning disorders- I can succeed (ICS).
- Trial name
- NCT01652651
- Testing
- I Can Succeed ICS
- Where
- Israel
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Connective Tissue Disease, Dissecting Aneurysm
Study of Heritable Connective Tissue Disorders
The purposes of this study are to identify the genes responsible for inherited connective tissue disorders and learn about the range of medical problems they cause.
- Conditions
- Connective Tissue Disease, Dissecting Aneurysm, Ehlers Danlos Syndrome, Marfan Syndrome
- Trial name
- NCT00001641
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Malnutrition, Diarrhea
WASH Benefits Kenya
The purpose of this study is to measure the independent and combined effects of interventions that improve sanitation, water quality, handwashing, and nutrition on child health and development in the first years of life.
- Conditions
- Malnutrition, Diarrhea, Child Development
- Trial name
- WASHB-Kenya (NCT01704105)
- Testing
- Water Quality, Sanitation, Handwashing
- Where
- Kenya
- Volunteers
- 8,246 people, healthy volunteers welcome
- Sponsor
- Innovations for Poverty Action
Autism Spectrum Disorder
Comparison of DSM-IV-TR and DSM-5 for ASD
The study aim is to prospectively compare DSM-IV-TR and DSM-5 criteria for Autism Spectrum Disorder (ASD) in a sample of 250 children and adolescents who meet DSM-IV-TR criteria for ASD and 150 children and adolescents referred…
- Trial name
- NCT02296502
- Testing
- DSM
- Where
- 5 sites in United States
- Volunteers
- 439 people
- Sponsor
- University of Pittsburgh
Autoimmune Hemolytic Anemia
Data Registry of Auto Immune Hemolytic Anemia
In autoimmune hemolytic anemia (AIHA) auto-antibodies directed against red blood cells (RBCs) lead to increased RBC clearance (hemolysis). This can result in a potentially life-threatening anemia.
- Trial name
- DRAIHA (NCT04024202)
- Where
- 2 sites in Netherlands
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Sanquin Research & Blood Bank Divisions
Mental Disorders, Severe
Measuring Development of Brain Responses to Vocal Sounds in Babies of Mums With Mental Illness
CAPRI-Voc examines the differences in how speech and environmental sounds are processed in the infant brain as they grow from 9 to 12 months.
- Trial name
- CAPRI-Voc (NCT04350294)
- Where
- United Kingdom
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Chronic Myelogenous Leukemia, Short Stature
Assessment Of Gh-Igf-1 Axis In Children With Chronic Myelogenous Leukemia (CML) In Remission
CML is a myeloproliferative disorder defined by the presence of the Philadelphia chromosome, which arises from the reciprocal translocation of genes on chromosomes 9 and 22.It is rare in childhood and accounts for 2-3% of all…
- Trial name
- NCT01901666
- Testing
- Growth Hormone
- Where
- India
- Volunteers
- 20 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Autism Spectrum Disorder
Efficacy of IMPACT in Infant Siblings of Children With ASD
Over a 5 year period infant and baby siblings of children with autism spectrum disorders (ASD) will be recruited to this study and will be randomized into 2 groups.
- Trial name
- IMPACT (NCT03274622)
- Testing
- Impact Parent Training, No Impact
- Where
- 2 sites in United States
- Volunteers
- 97 people
- Sponsor
- Vanderbilt University
Autism Spectrum Disorder
Predicting Treatment Response to Memantine in Autism Using Magnetic Resonance Spectroscopy
Memantine, an N-methyl-D-aspartate receptor antagonist, has been explored as a possible therapeutic agent that reduces the excitatory (glutamate) - inhibitory (gamma amino-butyric acid, GABA) imbalance in autism pathology and…
- Trial name
- NCT02811627
- Testing
- Memantine, Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Missouri-Columbia
Autism Spectrum Disorder
Exploring the Effectiveness of Dance as an Intervention to Promote Social-Emotional Health in Children With Autism Spectrum Disorder (ASD)
This study will explore the effectiveness of dance as an intervention to promote social-emotional health within children with ASD.
- Trial name
- ASD (NCT06295705)
- Testing
- Hip-Hop Dance
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Loma Linda University
Atopic Dermatitis
Comprehending Atopic Risk Elements
Skin barrier impairment and familial atopy have been implicated as crucial risk factors for the development of atopic dermatitis (AD).
- Trial name
- CARE (NCT04325451)
- Where
- 2 sites in Israel
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- MYOR Ltd.
Autism
Expanding Autism Diagnostic Biomarkers to Kenya
The study will use a non-invasive remote eye-tracking system (Eyelink Portable Duo) to acquire a short series of eye-tracking measures.
- Trial name
- KinleyET (NCT06685822)
- Testing
- Eyelink Portable Duo
- Where
- Kenya
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Indiana University
Congenital Hip Dysplasia
Erector Spinae Plane Block for Congenital Hip Dislocation Surgery
Developmental dysplasia of the hip (DDH) is one of the major disorder of the pediatric population with an incidence of 3 to 5 per 1000 children.
- Trial name
- NCT03949686
- Testing
- Saline Solution, Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Cochlear Hearing Loss
Development of Evidence-based Therapeutic Guidelines for Early SLA in Urdu-speaking Children With Cochlear Implants
Firstly global and regional literature on speech therapy after cochlear implantation focusing on Urdu-speaking populations and culturally relevant factors will be systematically reviewed.
- Trial name
- NCT07068373
- Testing
- Mixed method (Exploratory Sequential)
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Superior University
Influenza
B-cell Immunity to Influenza (SLVP017)- Year 5, 2013
In this exploratory study, investigators will be looking at immune response differences between age groups and between the two different vaccines given to identical twins and vaccine-naive young adults.
- Trial name
- NCT03020537
- Testing
- Fluzone
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Stanford University
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