Clinical trials: Developmental Disorder
Autism Spectrum Disorder, Autism
Dynamic Quantification of Social-Visual Engagement in Autism Spectrum Disorder (ASD)
The goal of this clinical study is to learn about the utility and performance of the EarliPoint System (™): Evaluation for Autism Spectrum Disorder to diagnose and assess autism spectrum disorder (ASD) in children ages 31-96…
- Trial name
- MEASURE-ASD2 (NCT05806216)
- Testing
- EarliPoint Diagnosis, Clinically Certain Expert Clinician Diagnosis (CC-ECD)
- Where
- 9 sites in United States
- Volunteers
- 929 people, healthy volunteers welcome
- Sponsor
- EarliTec Diagnostics, Inc
Sensory Processing Dysfunction
Sensory Processing Difficulties in Adults and Adolescents
The purpose of this study is to establish normative data for the Adult/Adolescent Sensory History (ASH) and to determine if the ASH is able to discriminate between individuals aged 13-95 years, with Autism Spectrum Disorder (ASD)…
- Trial name
- NCT02205658
- Where
- United States
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- The Spiral Foundation at OTA Watertown
Marfan Syndrome
Atenolol Versus Losartan in the Prevention of Progressive Dilation of the Aorta in Marfan Syndrome
The purpose of this study is to evaluate the efficacy of Losartan versus Atenolol in the progression of aortic dilatation in patients with Marfan syndrome.
- Trial name
- LO-AT-MARFAN01 (NCT01145612)
- Testing
- Losartan, Atenolol
- Where
- 2 sites in Spain
- Volunteers
- 140 people
- Sponsor
- Forteza, Albert, M.D.
Autism, ASD
Fronto-temporal tDCS Mproves Fluency & Empathy in ASD Kids
Interventional, prospective, randomized, double-blind, placebo-controlled and parallel assignment study, in which patients with Autism Spectrum Disorder (ASD) are two types of intervention by transcranial random noise stimulation…
- Trial name
- tDCS25112013 (NCT02004236)
- Testing
- tRNS Fronto-temporal cortex, tRNS over fusiform temporal cortex
- Where
- 2 sites in United Kingdom
- Volunteers
- 225 people
- Sponsor
- Spanish Foundation for Neurometrics Development
Autistic Disorder
Efficacy of Stellate Ganglion Block in Children With Autistic Disorder
The goal of this clinical trial is to explore efficacy of stellate ganglion block Children with Autistic Disorder. The main question it aims to answer is: Can stellate ganglion block improve the Autistic Disorder in children?…
- Trial name
- SGB-gudu (NCT06228157)
- Testing
- Routine therapy, Stellate ganglion block
- Where
- China
- Sponsor
- Zeng Changhao
Streptococcus Agalactiae Infection
Development of a Serocorrelate of Protection Against Invasive Group B Streptococcus Disease
A multicentre study to provide evidence that the relationship between an immune marker value (anti-GBS IgG concentration) and the probability of invasive GBS (iGBS) disease in infants less than 90 days of age is sufficiently…
- Trial name
- iGBS3 (NCT04735419)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 400 people
- Sponsor
- St George's, University of London
HIV, HIV - Human Immunodeficiency Virus
Intervention to Reduce HIV Related Stigma Among Pregnant and Postpartum Women
Purpose of this Study: The main purpose of this study is to adapt an existing evidence-based intervention, Project Accept Post-Test Support Services (PTSS) Module 3, specifically for pregnant and postpartum women living with HIV…
- Conditions
- HIV, HIV - Human Immunodeficiency Virus, Postpartum, Pregnancy
- Trial name
- WAT (NCT07064928)
- Testing
- Adapted Project Accept's Post-Test Support Services (PTSS) Module 3
- Where
- Ghana
- Volunteers
- 175 people
- Sponsor
- University of California, San Francisco
Autism Spectrum Disorder
SPARK Exercise Program and Game-based Training in Children With Autism Spectrum Disorder
This randomized controlled trial (RCT) will compare the effects of the SPARK program versus game-based circuit training on motor skills and social interaction in 22 children with Autism Spectrum Disorder (ASD) aged 5-12 years.
- Trial name
- NCT07579000
- Testing
- Structured Sports, Play, and Active Recreation for Kids Exercise program (SPARK), Game-based Training
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Autism Spectrum Disorder
Autism Spectrum Ambassador Program
The investigators are evaluating the implementation and the effectiveness of a medical student staffed support program (ASAP) for children diagnosed with Autism Spectrum Disorder coming into Penn State Hershey Children's Hospital…
- Trial name
- ASAP (NCT02842671)
- Testing
- Assigned Ambassador
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Autism Spectrum Disorder
Improving Dental Care and Oral Health in Children With Autism Spectrum Disorder
A randomized controlled trial (at sites) comparing the efficacy of the established AIR-P Dental Toolkit (control condition) to a combined regimen involving the Dental Toolkit and parent-mediated behavioral intervention…
- Trial name
- NCT03003221
- Testing
- AIR-P Dental Toolkit, Parent Training
- Where
- 2 sites in United States
- Volunteers
- 119 people
- Sponsor
- University of California, Irvine
Behavioral Symptoms, Autistic Disorder
Study of Aripiprazole in the Treatment of Children and Adolescents With Autistic Disorder (AD)
This study will compare the effectiveness (how well the drug works) of aripiprazole with placebo (fixed dose) in reducing serious behavioral problems in children and adolescents with a diagnosis of autistic disorder (AD).
- Trial name
- NCT00337571
- Testing
- Aripiprazole
- Where
- 31 sites in United States
- Volunteers
- 218 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Child Development, Growth
Health and Early Life Microbiota
The aim of this cohort is to identify environmental, lifestyle and genetic factors that modify the human intestinal microbiota development during the first years of life, and to identify early microbiota features that associate…
- Conditions
- Child Development, Growth, Allergy, Overweight
- Trial name
- HELMi (NCT03996304)
- Where
- Finland
- Volunteers
- 1,055 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Autism Spectrum Disorder
Oxytocin in Adolescents With Autism Spectrum Disorders
This study is design to evaluate the influence of oxytocin in some aspects of Autism Spectrum Disorder (ASD), such as, repetitive and stereotyped behavior, social skills, quality of life and disruptive behaviors.
- Trial name
- OXYASD (NCT02007447)
- Testing
- OCYTOCINA - SPRAY NASAL
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo General Hospital
Spinal Deformity
AI-Powered Scoliosis Auto-Analysis System Multicenter Development and Validations
The investigators aim to use artificial intelligence (AI) to help clinicians in diagnosing and assessing spinal deformities.
- Trial name
- NCT05146193
- Testing
- Nude back photo
- Where
- Hong Kong
- Volunteers
- 2,500 people
- Sponsor
- The University of Hong Kong
Autism Spectrum Disorder
Use of Immersive Virtual Reality to Train the Multisensory Processing Capacities of Children Aged 8 to 16 Years-old With an Autism Spectrum Disorder: Single-center Randomized Pilot Study in Parallel Groups - SEVIRE. (Sensory Virtual Reality)
Autism Spectrum Disorder (ASD) is defined as a neurodevelopmental disorder that affects the functioning and development of social communication (DSM5 - 2013).
- Trial name
- SEVIRE (NCT05171244)
- Testing
- virtual reality training, usual care
- Where
- 2 sites in France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Tours
Healthy Children
To Investigate the Effects of Bifidobacterium Animalis Subsp. Lactis XLTG11 on Growth and Development, Incidence of Allergy and Immune Function in Infants
This study is a 180-day randomized, double-blind, placebo-controlled trial involving healthy infants and young children under 3 years of age with elevated allergy risk.
- Trial name
- NCT07490587
- Testing
- Probiotic
- Where
- 2 sites in China, Malaysia
- Volunteers
- 366 people, healthy volunteers welcome
- Sponsor
- Min-Tze LIONG
Autism Disorder
The Effectiveness of a Parent Training Program for Children With Autism Spectrum Disorder and High-Risk Infants: A Case-Control Study
The aim of this study is to evaluate the effectiveness of a parent training program on the severity of autism-related symptoms in two groups: (1) infants under the age of 2 who show early signs of autism, and (2) children aged 2…
- Trial name
- PTP (NCT07075614)
- Testing
- Parent Training Program, routine care
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Umraniye Education and Research Hospital
Pectus Excavatum
Lung Ultrasound for the Postoperative Diagnosis of Pneumothorax in Children
This study will be conducted to determine the advantages and limitations of sonography compared with chest radiography, in the detection of post procedure iatrogenic pneumothorax in patients underwent to Pectus Excavatum (PE)…
- Trial name
- ECO_NUSS (NCT03073616)
- Testing
- Lung ultrasound
- Where
- Italy
- Volunteers
- 66 people
- Sponsor
- Nicola Disma, MD
Autism Spectrum Disorders
Interactive Guidance Therapy With Video Feed-back of Parent and Child With Autism Spectrum Disorder
The purpose of this study is to assess the effect of Interactive Guidance Therapy with video feed back (IGT) of parent and child with Autism Spectrum Disorder, under three years of age, using a Single Case Experimental Design…
- Trial name
- GIETSA (NCT04607616)
- Testing
- Baseline sessions TAU, Interactive guidance therapy, Developmental and diagnostic assessments
- Where
- 4 sites in France
- Volunteers
- 27 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Healthy
Development of Early Diagnostic Techniques and Setup of Local Therapeutic Guidelines and Standards
End-stage renal disease (ESRD) is a healthy, social and economic threat worldwide. In the past ten years, the incidence and prevalence of ESRD patients have tremendously increased, ranking at the top in the world.
- Trial name
- Hmodialysis (NCT00912704)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
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