Clinical trials: Developmental Language Disorders
Autism, Language Acquisition
Study of Toddlers With Language Delay
The purpose of this study is to learn more about risk factors for autism by studying the behavior and brain functioning of toddlers with early communication delays and typically developing toddlers.
- Conditions
- Autism, Language Acquisition, Language Development, Toddlers
- Trial name
- NCT01339767
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Social Communication Disorder, Autism
Feasibility Trial of Parent-delivered Social Communication Program
The Hanen Centre®'s More Than Words® (MTW) program is a globally used, parent coaching intervention delivered by speech-language pathologists (SLPs) to parents of children with social communication challenges, including those who…
- Trial name
- NCT06847347
- Testing
- More Than Words®
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- Western University, Canada
Dyslexia, Dyslexia, Developmental
Impact of Non-invasive Brain Stimulation on Learning Novel Spoken Words
The purpose of the proposed study is to use transcranial magnetic stimulation (TMS) to evaluate a neurobiological model of spoken word learning in older youth.
- Conditions
- Dyslexia, Dyslexia, Developmental, Learning; Developmental Disorder, Reading
- Trial name
- NCT06387615
- Testing
- Active cTBS
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Georgia State University
Autism Spectrum Disorder, Complication of Prematurity
Correlation of CXCR4 Expression in Premature Infants With a Diagnosis of Autism at 24 Months
Preterm children are at increased risk for autism spectrum disorders, with an estimated rate of 10%. In the US, about 1 in 8 pregnancies ends with a premature birth.
- Trial name
- ASD-CXCR4 (NCT01686685)
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Developmental Disability, Developmental Dyslexia
Postural Control, Grip Strength and Body Posture in Children With Intellectual Disability and Dyslexia
This study investigates physical changes in children with Dyslexia and Intellectual Disability. Participants divided into three groups and Body Posture, Postural Control and Hand Grip Strengths was evaluated.
- Conditions
- Developmental Disability, Developmental Dyslexia, Intellectual Disability
- Trial name
- NCT04250701
- Testing
- Body Posture Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ahmet Emir
Developmental Language Disorder
Semantic Learning Deficits in School Age Children With Developmental Language Disorder
School age children with developmental language disorder (DLD) have known semantic learning deficits but what is less well understood is why semantic learning is difficult for these children.
- Trial name
- NCT04508699
- Testing
- semantic learning
- Where
- United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Stuttering
Genetic Factors Related to Stuttering
Stuttering is an abnormality in speech that affects the rhythm of speech. People who stutter know what they wish to say, but at the time are unable to say it because of involuntary repetition, unnecessary lengthening…
- Trial name
- NCT00001602
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Autism Spectrum Disorder
Intervention for Toddlers at Risk for Autism Spectrum Disorders (ASD)
This research is being done to test the effectiveness of an early intervention model for very young children at high risk for autism spectrum disorders (ASD) and their families.
- Trial name
- NCT01179841
- Testing
- Playgroup, Parent Training
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Healthy, Speech Disorders
Development of Normative Ultrasound Databases of Tongue Surface Configuration
Our past ultrasound research has indicated a need for baseline normative tongue data against which to compare our disordered speech populations.
- Trial name
- NCT00001218
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Autism, Autism Spectrum Disorder
Milieu Teaching-AV: Adaptation of Milieu Teaching That Encourages Looking to the Mouth
This project will look at Milieu Teaching (i.e., a language intervention) that encourages looking to audiovisual speech cues (Milieu Teaching-AV) for infants with autistic older siblings (Baby Sibs), who are highly likely be…
- Conditions
- Autism, Autism Spectrum Disorder, Autism, Susceptibility to, 6
- Trial name
- MilieuTeach-AV (NCT07494513)
- Testing
- Milieu Teaching-AV, Milieu Teaching-NoAV
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Father Flanagan's Boys' Home
Autism Spectrum Disorder, Autistic Disorder
Telehealth Parent-Implemented Intervention for Young Children With Autism Spectrum Disorder (ASD)
The primary objective of this research study is to improve outcomes involving core social-communication symptoms for young children with ASD or social communication delays by increasing access to clinically validated early…
- Conditions
- Autism Spectrum Disorder, Autistic Disorder, Active Autistic Disorder, Autism
- Trial name
- NCT05176808
- Testing
- Early Achievements- Parent Coaching Intervention
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Infant Development, Preterm Birth
Auditory Environment by Parents of Preterm Infants
Data on parent-infant physical closeness and infants' auditory environment will be collected among preterm infants when they are at gestational age of 32 to 34 weeks.
- Conditions
- Infant Development, Preterm Birth, Language Development
- Trial name
- APPLE (NCT04826978)
- Testing
- Auditory environment
- Volunteers
- 116 people
- Sponsor
- Turku University Hospital
Autism Spectrum Disorders
Transcranial Direct Current Stimulation and Autism
This research is being done to determine whether transcranial direct current stimulation (tDCS) can improve certain mental abilities, such as speech, language and other efforts at communication in individuals with autism.
- Trial name
- NCT01603225
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Johns Hopkins University
Developmental Delays
Empower EI: Comparing Early Intervention Approaches to Improve Communication in Toddlers With Developmental Delays
This study is testing three ways to deliver Early Intervention (EI) services for toddlers with developmental disabilities (DD). Children enrolled in EI speech therapy will receive one of three approaches: 1.
- Trial name
- NCT07227974
- Testing
- Therapist-Delivered Early Intervention Approach, Caregiver Coaching Early Intervention Approach, Parents Taking Action
- Where
- United States
- Volunteers
- 1,269 people
- Sponsor
- Northwestern University
Learning Disorders, Specific, Developmental Disability
Using a New Calibrated Tool in Specific Language and Learning Disorders : the BMTi
The group of experts at HAS has defined the places of first and second-line workers in specific disorders of development and learning, as defined in the international diagnostic classifications International Classification of…
- Trial name
- ValidBMTI (NCT03919357)
- Testing
- BMT-i
- Where
- 16 sites in France, Martinique
- Volunteers
- 229 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Developmental Language Disorder, Speech Sound Disorder
A Developmental Framework For Linking Phonological And Morpho-syntactic Sequential Pattern Rules In DLD: Production
The broad aim of this clinical study is to assess the hypothesis that morphological and phonological deficits are linked by a broader deficit in sequential pattern learning.
- Conditions
- Developmental Language Disorder, Speech Sound Disorder, Specific Language Impairment
- Trial name
- NCT04558541
- Testing
- Sensitivity to phonological rules, Sensitivity to semantic category cues.
- Where
- 2 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Father Flanagan's Boys' Home
Iron Deficiency Anemia
Iron Deficiency Anemia and Psychosocial Stimulation
In developing countries, poor nutrition, high morbidity, poverty, poor parental education and stimulation in the home, all detrimentally affect children's development.
- Trial name
- IDA (NCT00668694)
- Testing
- Stimulation
- Where
- Bangladesh
- Volunteers
- 434 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Down Syndrome
Oral Language in Children With Down Syndrome
The objective of this research is to verify the language of children with Down syndrome concerning lexical, syntactic and semantic aspects using MLU.
- Trial name
- NCT00952354
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Autism Disorder, Language Development Disorders
Rural Autistic Individuals - Supporting Expression
This research study investigates how hand gestures can support language comprehension and communication skills of hearing speaking, non-speaking, and/or minimally verbal individuals with Autism Spectrum Disorders (ASD), who are…
- Conditions
- Autism Disorder, Language Development Disorders, ADHD, Typical Development
- Trial name
- RAISE (NCT07054866)
- Testing
- Speech-Gesture combinations
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Montana State University
Creatine Deficiency, X-linked
Observational Study of Males With Creatine Transporter Deficiency
The objectives of this study are to illustrate the clinical, neuro/electrophysiologic, biochemical, and developmental status and progression of patients with Creatine Transporter Deficiency (CTD) and to evaluate the utility of…
- Trial name
- Vigilan (NCT02931682)
- Where
- 10 sites in United States, Canada
- Volunteers
- 50 people
- Sponsor
- Ultragenyx Pharmaceutical Inc