Clinical trials: Developmental Risk
Metabolic Syndrome
Determination of Risk Factors for the Development of Obesity and Hypertension in Children According to Perinatal Programming of Metabolism
to determine the risk factors for developing obesity in children with exogenous-constitutional obesity and arterial hypertension, according to the theories of early programming of metabolism
- Trial name
- NCT04611412
- Testing
- Risk Factors
- Where
- Uzbekistan
- Volunteers
- 55 people
- Sponsor
- Samarkand State Medical Institute
Ulcerative Colitis, Dysplasia
Development of Dysplasia in the Pelvic Pouch in Patients With Ulcerative Colitis (UC) and Risk Factors
The purpose of this study is to study development of dysplasia in the ileal mucosa among patients with Ulcerative Colitis and who previous have hade risk factors for developing cellular changes/dysplasia, i.e.
- Conditions
- Ulcerative Colitis, Dysplasia, Surgery
- Trial name
- NCT01764542
- Testing
- Endoscopy and biopsy
- Where
- Sweden
- Volunteers
- 56 people
- Sponsor
- Mattias Block
Neurodevelopmental Disorders, Neurodevelopmental Disorders and Developmental Abnormalities
Effectiveness of the COPCA Program in Infants at Risk of Neurodevelopmental Disorders
The purpose of this clinical trial is to evaluate whether the COPCA® program (Coping with and Caring for Infants with Special Needs) is more effective than conventional pediatric physiotherapy and parent education in improving…
- Trial name
- COPCA (NCT07387627)
- Testing
- Coping with and Caring for Infants with Special Needs, Parental Education Program, Conventional Pediatric Physiotherapy
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- University of Seville
Autism Spectrum Disorder
Intervention for Toddlers at Risk for Autism Spectrum Disorders (ASD)
This research is being done to test the effectiveness of an early intervention model for very young children at high risk for autism spectrum disorders (ASD) and their families.
- Trial name
- NCT01179841
- Testing
- Playgroup, Parent Training
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Breast Cancer
Exemestane in Reducing Breast Density in Postmenopausal Women at Risk for Breast Cancer
RATIONALE: High estrogen levels may be associated with dense breast tissue and an increased risk of developing breast cancer. Exemestane may be effective in preventing the development of breast cancer by decreasing estrogen…
- Trial name
- NCT00066586
- Testing
- exemestane
- Where
- 12 sites in United States, Canada
- Volunteers
- 98 people
- Sponsor
- NCIC Clinical Trials Group
Child Development
Effects of Application of a Motor Programme on Neurological Maduration in Children
The persistence of primitive reflexes in school-age children can affect neuromotor maturation. Some studies link the persistence of primitive reflexes with specific learning difficulties, low academic performance…
- Trial name
- Move&Learn (NCT06030310)
- Testing
- The developmental Exercise Programme of INPP
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fundació Universitària del Bages
Autism Spectrum Disorder, Neurodevelopmental Disorders
Evaluation of a Novel Intervention for Infants At Risk for Neurodevelopmental Disorders
This study entails a "proof of concept" evaluation of a novel intervention, Parents and Infants Engaged (PIE), for prodromal infants at-risk for neurodevelopmental disorders (NDs).
- Trial name
- PIE (NCT03388294)
- Testing
- Parents and Infants Engaged
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Transient Tachypnea of Newborn and Fetal Acidosis
Impact Of Maternal Spinal Anesthesia-Induced Hypotension At Scheduled Cesarean Delivery On Risk Development Of Transient Tachypnea Of Newborn And Fetal Acidosis
We will evaluate the association between transient tachypnea of newborns and fetal acidosis development to the degree and duration of maternal hypotension and anesthesia to delivery time during spinal anesthesia at scheduled…
- Trial name
- NCT06383624
- Where
- Egypt
- Volunteers
- 115 people
- Sponsor
- Benha University
Infant Development
Investigation of the Relationship Between Development, Neurological Assessment and Object Permanence in High Risk Infants.
The aim of the study is to examine the relationship between development, neurological assessment and object permanence in risky infants aged 7-16 months.
- Trial name
- NCT05749796
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Tokat Gaziosmanpasa University
Periodontitis
Predicting Periodontal Treatment Success Using Machine Learning in Periodontitis Patients
This retrospective observational study aims to develop treatment-specific machine learning models for predicting tooth-level periodontal treatment outcomes among teeth treated with non-surgical periodontal treatment, conventional…
- Trial name
- NCT07485946
- Testing
- Conventional Flap Surgery, Regenerative Flap Surgery, Phase-1 Periodontal Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people
- Sponsor
- Akdeniz University
AML
Incidence and Risk Factors for the Development of Invasive Fungal Infection in Patients Diagnosed With Acute Myeloblastic Leukemia (HIFA)
Patients diagnosed with acute myeloblastic leukemia (AML) who receive intensive chemotherapy treatment have a high incidence of invasive fungal infection (IFI).
- Trial name
- HIFA (NCT07060612)
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Pregnancy, Sexually Transmitted Diseases
Development and Testing of a Clinic-Based Intervention to Increase Dual Protection Against Unintended Pregnancy and Sexually Transmitted Diseases (STDs) Among High Risk Female Teens
This trial will evaluate a multi-component, clinic-based intervention aimed at increasing dual protection strategy selection and adherence among young African American females at an urban family planning clinic.
- Trial name
- 2Gether (NCT02291224)
- Testing
- Interactive multimedia platform, Intervention arm counseling, Standard of care counseling
- Where
- United States
- Volunteers
- 709 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Posterior Fossa Tumors, Pediatric Tumor of Brain
Predicting Cognitive Dysfunction After Pediatric Posterior Fossa Tumor Surgery
The goal of this observational study is to develop and validate a clinical prediction model to identify risk factors for long-term cognitive dysfunction in children (ages 0-18 years) who have undergone surgical resection of a…
- Trial name
- NCT07350382
- Testing
- Not applicable- observational study
- Where
- China
- Volunteers
- 600 people
- Sponsor
- West China Hospital
Diabetes, Prediabetes
Meta-analyses of Pasta as Part of Low Glycemic Index Diets and Adiposity
Pasta is an important example of a food which can lower the glycemic index (GI) of the diet, a property that has been exploited extensively in studies of low GI dietary patterns.
- Conditions
- Diabetes, Prediabetes, Overweight, Obesity
- Trial name
- NCT02961088
- Testing
- Pasta as part of a low GI/GL diet
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Disorders of Sexual Development
Disorders of Sexual Development and Gonadal Tumor Risk
Disorders of Sexual Development are rare and represent a spectrum of heterogeneous pathologies. The risk of developing a malignant gonadal germ cell tumor (MGCT) exists and varies according to the etiology.
- Trial name
- DEV-GEN-RiTuGo (NCT06682078)
- Testing
- Not applicable . Non-interventional retrospective study, only on datas.
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Hospices Civils de Lyon
Child Development, Early Child Development
Intergenerational Risk and Resilience of Rohingya in Displacement
The iRRRd study is an ongoing prospective longitudinal prenatal birth cohort study based in Cox's Bazar, Bangladesh. Between February 2023 and March 2024, 2,888 pregnant women were enrolled (approximately 80% Rohingya refugees…
- Conditions
- Child Development, Early Child Development, Mental Health, PTSD - Post Traumatic Stress Disorder
- Trial name
- iRRRd (NCT07758283)
- Where
- Bangladesh
- Volunteers
- 2,200 people
- Sponsor
- New York University
Malignant Neoplasm
Music Therapy Video Development in Improving Communication, Emotional Distress, and Recovery in Adolescents/Young Adults Undergoing Treatment for High-Risk Cancer and Their Parents
This randomized trial studies how well music therapy and parents' education work in improving communication, emotional distress, and recovery in adolescents/young adult patients undergoing treatment for high-risk cancer and their…
- Trial name
- NCT01556256
- Testing
- Caregiver-Related Intervention or Procedure, Music Therapy, Quality-of-Life Assessment
- Where
- 8 sites in United States
- Volunteers
- 124 people
- Sponsor
- Children's Oncology Group
Obesity, Children
Polygenic Risk Score to Predict Weight Loss Intervention in Children With Obesity
Children with obesity are prone to suffering from metabolic diseases, which undoubtedly increases the burden of public health. Since obesity is a multiple gene disease, a comprehensive approach using polygenic risk scores (PRS)…
- Trial name
- NCT05466097
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- Far Eastern Memorial Hospital
Migraine Headache, Headache
Clinical Decision Rule for Pediatric Intracranial Pathology
The purpose of this study is to develop a clinical decision rule for patients seen in the pediatric emergency department for possible intracranial pathology.
- Trial name
- NCT02742272
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Breast Feeding, Cardiovascular Diseases
Effect of Breastfeeding Optimization on Early Vascular Development
This study aims to find out whether breast feeding optimization will increase breast feeding rates and to evaluate its effect on cardiovascular risk and general health of children.
- Trial name
- BRAVO (NCT01566812)
- Testing
- Breast feeding optimization, Usual care
- Where
- Indonesia
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia