Clinical trials: Dexamethasone
Non-Hodgkins Lymphoma, Hodgkin's Disease
Irinotecan, Vincristine, and Dexamethasone In Children With Relapsed And/Or Refractory Hematologic Malignancies
The purpose of this study is to estimate the maximum tolerated dose of dexamethasone given for 5 consecutive days when combined with fixed doses of irinotecan (given IV, qd x 5, 2 days off, qd x 5) and vincristine (given IV, 2…
- Conditions
- Non-Hodgkins Lymphoma, Hodgkin's Disease, Acute Lymphoblastic Leukemia
- Trial name
- NCT00718757
- Testing
- Dexamethasone, Irinotecan, Vincristine
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- St. Jude Children's Research Hospital
HELLP Syndrome
Dexamethasone Efficacy in HELLP I Syndrome
The purpose of this study is to determine the efficacy of dexamethasone for treatment of HELLP I (hemolysis, elevated liver enzymes and low platelet count) syndrome.
- Trial name
- NCT01138839
- Testing
- Dexamethasone, sterile water
- Where
- Colombia
- Volunteers
- 160 people
- Sponsor
- Universidad del Valle, Colombia
Arm
The Effect of Dexamethasone Administration Route in Pediatric Brachial Plexus Block
This study aims to assess the impact of the administration route of dexamethasone (intravenous vs. perineural) on postoperative pain and inflammatory response in pediatric patients undergoing hand/wrist surgery.
- Trial name
- NCT07061678
- Testing
- perineural dexamethasone, intravenous dexamethasone, 0.2ml/kg 0.2% ropivacaine
- Where
- 2 sites in Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Myelodysplastic Syndromes
Calcitriol and Dexamethasone in Patients With Myelodysplastic Syndromes
This is a study to determine the response rate in patients with myelodysplastic syndromes treated with calcitriol and dexamethasone.
- Trial name
- NCT00030069
- Testing
- Calcitriol, Dexamethasone
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Pittsburgh
Retinopathy of Prematurity (ROP)
To Assess the Effect of Dexamethasone Eye Drops on the Retinopathy of Prematurity Outcome
The purpose is to compare the treatment frequency of preterm infants who developed severe Retinopathy of Prematurity (ROP) during the years 2015-2018 with 2020-2021 in the country, using the statistical method 'difference in…
- Trial name
- NCT06775353
- Testing
- Dexamethasone eyedrop
- Where
- Sweden
- Volunteers
- 2,017 people, healthy volunteers welcome
- Sponsor
- Region Skane
Hip Dysplasia, Hip Disease
The Effect of Dexamethasone Administration Route in PENG Block for Pediatric Hip Surgery
This study aims to assess the impact of the administration route of dexamethasone (intravenous vs. perineural) on postoperative pain, inflammatory response, and neuromonitoring parameters in pediatric patients undergoing hip…
- Trial name
- NCT06789367
- Testing
- perineural Dexamethasone 4mg, intravenous Dexamethsone 4mg
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Orbital Cellulitis
Dexamethasone vs. Placebo in Children and Youth Hospitalized for Orbital Cellulitis
The goal of this pilot randomized controlled trial is to understand whether we can successfully conduct a larger definitive clinical trial in the future.
- Trial name
- VISION (NCT07345819)
- Testing
- Dexamethasone 0.3mg/kg
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- The Hospital for Sick Children
Primary Central Nervous System Lymphoma
Open Randomized Prospective Clinical Study of R-FPD Versus R-MAD Regimen in the Treatment of Primary Central Nervous System Lymphoma
Comparison of the efficacy and safety of rituximab combined with fotemustine, pemetrexed, dexamethasone and rituximab in combination with methotrexate, cytarabine and dexamethasone as first-line regimens in the treatment of…
- Trial name
- NCT04083066
- Testing
- rituximab in combination with methotrexate, cytarabine and dexamethasone
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Mingzhi Zhang
Anesthesia, Strabismus
Post-Operative Nausea and Vomiting in Children Submitted to Strabismus Surgery
Background: Postoperative nausea and vomiting (PONV) is one of the main causes of patient and family dissatisfaction, which may delay the onset of oral intake and postpone discharge.
- Conditions
- Anesthesia, Strabismus, PONV
- Trial name
- NCT04060771
- Testing
- Palonosetron, Dexamethasone
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Universidade Federal Fluminense
Blepharoconjunctivitis
Comparative Study of AzaSite Plus Compared to AzaSite Alone and Dexamethasone Alone to Treat Subjects With Blepharoconjunctivitis
The purpose of this study is to determine if AzaSite Plus is effective and safe for the treatment of blepharoconjunctivitis compared to AzaSite alone and Dexamethasone alone.
- Trial name
- NCT00754949
- Testing
- 1% Azithromycin and 0.1% Dexamethasone, 1% Azithromycin, 0.1% Dexamethasone
- Sponsor
- Sun Pharmaceutical Industries Limited
Postoperative Pain
Fascia Iliaca Block Supplemented With Perineural Vs Intravenous Dexamethasone
Split-thickness skin grafting is the current standard of care for the reconstructive procedures in managing burn injuries and traumatic tissue defects.
- Trial name
- Interventional (NCT04561856)
- Testing
- Dexamethasone
- Volunteers
- 99 people
- Sponsor
- Assiut University
Asthma in Children
EFFECTIVENESS OF SINGLE DOSE ORAL DEXAMETHASONE VERSUS MULTIDOSE PREDNISOLONE FOR TREATMENT OF ACUTE EXACERBATIONS OF ASTHMA AMONG CHILDREN ATTENDING THE EMERGENCY DEPARTMENT OF CHILDREN HOSPITAL, ISLAMABAD
In this Study i'll compare the effectiveness of two drugs used in acute exacerbation of asthma by their sideffects, complaince and improvement in the PRAM score. The better one would be adapted in our clinical practice.
- Trial name
- NCT05850143
- Testing
- Dexamethasone, Prednisolone
- Where
- Pakistan
- Volunteers
- 192 people
- Sponsor
- DR. MOHAMMAD ALI ARIF
Inflammation and Pain Associated With Cataract Surgery
2nd Study to Assess ISV-305 Compared to Vehicle for Treatment of Inflammation and Pain Associated With Cataract Surgery
The purpose of this study is to evaluate the ocular safety, tolerability, and efficacy of ISV-305 (Dexamethasone in DuraSite® 2) compared to Vehicle in the treatment of inflammation and pain associated with cataract surgery.
- Trial name
- ISV-305 (NCT03192150)
- Testing
- ISV-305, Vehicle
- Where
- United States
- Volunteers
- 246 people
- Sponsor
- Sun Pharmaceutical Industries Limited
Analgesic Effect
Comparison of Caudal Blockade and Dorsal Penile Nerve Block With and Without the Intravenous Administration of Dexamethasone for Analgesia After Paediatric Male Circumcision
Male infant circumcision is a frequently performed, but painful procedure. A variety of methods, both systemic and locoregional, have been developed to overcome postoperative pain after circumcision.
- Trial name
- NCT05598255
- Testing
- Dexamethasone, Caudale Blockade with levobupivacaine, Dorsal penile nerve block with levobupivacaine
- Where
- Belgium
- Volunteers
- 54 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Caudal Block
Caudal Combination of Dexamethasone and/or Dexmedetomidine to Bupivacaine in Pediatric Hypospadias Surgery
One of the most commonly used regional anesthetic techniques in pediatric surgeries is the caudal epidural block. Its main disadvantage remains the short duration of action. Hence, different additives have been used.
- Trial name
- NCT03261921
- Testing
- Dexamethasone, Dexmedetomidine, Bupivacaine
- Volunteers
- 63 people
- Sponsor
- Cairo University
Edema, Pain
Comparison of Hyaluronidase and Dexametasone in Reduction of Postoperative Edema
The present study is designed to reveal effectiveness of hyaluronidase and dexamethasone on reduction of postoperative edema, pain, trismus, and infection.
- Conditions
- Edema, Pain, Trismus, Infection, Surgical Site
- Trial name
- NCT05466604
- Testing
- Hyaluronidase Injection mesomedica, Dexamethasone dekort
- Where
- 2 sites in Cyprus, Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Blood Disease
The Combination of IVIG, Dexamethasone and a Megadose of PBSCs for Decreasing DSAs
Donor-specific antibodies (DSAs) are essential causes of graft rejection in haploidentical hematopoietic stem cell transplantation (haplo-HSCT). DSAs are unavoidable for some patients who have no alternative donor.
- Trial name
- NCT06471478
- Testing
- intravenous immunoglobulin, dexamethasone and a megadose of peripheral-blood stem cell transfusion
- Where
- China
- Volunteers
- 11 people
- Sponsor
- Hematology department of the 920th hospital
Impacted Mandibular Third Molar Extraction
Piezo-surgery Technique and Intramuscular Dexamethasone Injection to Reduce Postoperative Pain After Impacted Mandibular Third Molar Surgery
The purpose of my study is to test the effect of using piezosurgery and dexamethasone injection in the surgical extraction of impacted mandibular third molars, on Postoperative Pain.
- Trial name
- NCT04889781
- Testing
- Dexamethasone injection, Piezosurgery, Conventional Rotatory instruments
- Where
- Lebanon
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Central Military Healthcare - Oral and Maxillofacial Surgery Department
Bronchiolitis
Epinephrine, Dexamethasone, and Hypertonic Saline in Bronchiolitis, Randomised Clinical Trial of Efficacy and Safety
In infancy, bronchiolitis is the most common acute infection of the lower respiratory Tract. The current treatment of bronchiolitis is controversial.
- Trial name
- NCT01834820
- Testing
- Epinephrine and Dexamethasone, Hypertonic Saline, Normal Saline
- Where
- Mexico
- Volunteers
- 120 people
- Sponsor
- Hospital General Naval de Alta Especialidad - Escuela Medico Naval
Acute Lymphoblastic Leukemia ALL
Ribociclib in Combination With Everolimus and Dexamethasone in Relapsed ALL
This research study is evaluating a drug called ribociclib (LEE011) given in combination with everolimus and other standard of care chemotherapy drugs as a possible treatment for relapsed or refractory ALL.
- Trial name
- NCT03740334
- Testing
- Ribociclib, Dexamethasone, Everolimus
- Where
- 12 sites in United States
- Volunteers
- 45 people
- Sponsor
- Dana-Farber Cancer Institute