Clinical trials: Dexmedetomidine Infusion
Dexmedetomidine Infusion, Pediatric
Comparison of Caudal Block Versus Dexmedetomidine Infusion in Pediatric Patients Undergoing Hypospadias Repair Surgery
Pain is one of the most misunderstood, underdiagnosed, and untreated medical problems, particularly in children. New Joint Commission on Accreditation of Health Care Organization regards pain as fifth vital sign and requires…
- Conditions
- Dexmedetomidine Infusion, Pediatric, Hypospadias Repair Surgery
- Trial name
- NCT04331418
- Testing
- Dexmedetomidine, caudal block
- Where
- Egypt
- Volunteers
- 135 people
- Sponsor
- Tanta University
Analgesia
Opioid Sparing Analgesia: Dexmedetomidine Versus Lidocaine for Intracranial Surgeries in Children
Perioperative pain control is necessary in children as inadequate treatment may lead to progression of perception of pain and development of chronic pain in the future.
- Trial name
- NCT04535089
- Testing
- Dexmedetomidine injection, Lidocaine Iv
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Analgesic, Sedative
Analgesic and Sedative Effect of Fentanyl Versus Dexmedetomidine Infusion in Post-Operative Mechanically Ventilated Children After Open Abdominal Surgeries
This study aimed to compare the efficacy and safety of fentanyl versus dexmedetomidine infusion in this population.
- Conditions
- Analgesic, Sedative, Fentanyl, Dexmedetomidine
- Trial name
- NCT06994273
- Testing
- Fentanyl, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Tanta University
Anesthesia
Dexmedetomidine and Desflurane Consumption
The aim of this study is to calculate desflurane consumption when combined with intraoperative dexmedetomidine infusion guided by bispectral index (BIS)
- Trial name
- NCT02652312
- Testing
- Dexmedetomidine, Ondansetron, fentanyl
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Theodor Bilharz Research Institute
Postoperative Delirium
Dexmedetomidine in Reducing Incidence of Emergence Agitation After Nasal Surgery
Various pharmacological interventions have been attempted previously to prevent postoperative EA with variable results. These include use of opioids, propofol, midazolam, ketamine, magnesium and alpha-2 agonists like clonidine…
- Trial name
- NCT05634148
- Testing
- Dexmedetomidine
- Where
- Saudi Arabia
- Volunteers
- 42 people
- Sponsor
- Security Forces Hospital
Postoperative Agitations in Pediatric Patients
Dexmedetomidine Versus Magnesium Infusion in Reducing Agitations in Pediatric Patients Undergoing Adenotonsillectomy
The aim of this study is evaluating the efficacy and safety of dexmedetomidine versus Magnesium for reducing emergence agitation after adenotonsillectomy in children.
- Trial name
- NCT05164627
- Testing
- Dexmedetomidine, Magnesium Sulphate, Normal saline
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Transposition of the Great Arteries, Tetralogy of Fallot
A Phase I Study of Dexmedetomidine Bolus and Infusion in Corrective Infant Cardiac Surgery: Safety and Pharmacokinetics
The purpose of this Phase I study is to determine the safety of a drug called dexmedetomidine (DEX) as part of a balanced general anesthetic and sedative strategy for neonates and infants undergoing corrective cardiac surgery…
- Conditions
- Transposition of the Great Arteries, Tetralogy of Fallot, Ventricular Septal Defect
- Trial name
- NCT01915277
- Testing
- Dexmedetomidine
- Where
- 4 sites in United States
- Volunteers
- 119 people
- Sponsor
- Carelon Research
Pain
Dexmedetomidine Infusion in Hypospadias Surgery
The investigators hypothesize that giving Dexmedetomidine in combination with Fentanyl for pediatric patients undergoing hypospadias surgery, will reduce the fentanyl requirement for intraoperative and postoperative analgesia.
- Trial name
- NCT00926705
- Testing
- Dexmedetomidine and Fentanyl, Fentanyl
- Where
- Jordan
- Volunteers
- 48 people
- Sponsor
- University of Jordan
Anxiety, Postoperative Pain
Evaluation of the Postoperative Agitation Prevention and Analgesic Efficacy of Perioperative Dexmedetomidine Infusion in a Pediatric Patient Group to Undergo Tonsillectomy and Adenoidectomy
Dexmedetomidine is a drug known for its pain-relieving and restlessness-reducing effects. The purpose of this run is to use the association between this use during surgery and the attrition of post-operative pain and discomfort.
- Conditions
- Anxiety, Postoperative Pain, Bleeding
- Trial name
- NCT05986942
- Testing
- Fentanyl, Dexmedetomidine
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Burak Omur
Headache, Tumor
Dexmedetomidine and Propofol for Pediatric MRI Sedation
The purpose of this study is to compare the results of combining two anesthetic medications (dexmedetomidine and propofol) in low doses with a standard dose of a single drug that is commonly used to provide sedation/anesthesia…
- Conditions
- Headache, Tumor, Seizure Disorder, Neurofibromatoses
- Trial name
- NCT03513757
- Testing
- propofol, Dexmedetomidine, Glycopyrrolate
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Medical College of Wisconsin
Dexmedetomidine, Ketofol
Dexmedetomidine vs Ketofol on Delirium in Children Undergoing Congenital Inguinal Hernia Repair
The aim of this study is to compare the effect of dexmedetomidine versus ketofol on the incidence of the emergence delirium in children undergoing congenital inguinal hernia repair.
- Conditions
- Dexmedetomidine, Ketofol, Delirium, Hernia
- Trial name
- NCT05786833
- Testing
- Dexmedetomedine, Ketofol, isotonic saline 0.9%
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Spine Cancer, Anesthesia
Dexmedetomidine Infusion on Intraoperative Propofol,Fentanyl Requirements in Spine Surgery for Pediatric Cancer Patients
The purpose of this trial is to investigate whether the effect of a low-dose dexmedetomidine infusion will decrease propofol consumption or not through a double blinded randomized controlled trial done in children cancer hospital…
- Trial name
- NCT05493228
- Testing
- Precedex Injectable Product, Saline
- Where
- Egypt
- Volunteers
- 38 people
- Sponsor
- Children's Cancer Hospital Egypt 57357
Anxiety, Postoperative Pain
Evaluation of the Postoperative Agitation Prevention and Analgesic Efficacy of Perioperative Dexmedetomidine Infusion in a Pediatric Patient Group to Undergo Dental Treatment
Dexmedetomidine is a drug known for its pain-relieving and restlessness-reducing effects. The purpose of this run is to use the association between this use during surgery and the attrition of post-operative pain and discomfort.
- Conditions
- Anxiety, Postoperative Pain, Nausea
- Trial name
- NCT06097169
- Testing
- Fentanyl, Dexmedetomidine
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Medipol University
Obstructive Sleep Apnea
Decrease Emergence Agitation and Provide Pain Relief for Children Undergoing Tonsillectomy & Adenoidectomy
Pediatric tonsillectomy (with or without adenoidectomy) is a brief but painful surgery carried out in children who very often also present with obstructive sleep apnea. To provide pain relief, i.e.
- Trial name
- NCT00468052
- Testing
- dexmedetomidine, fentanyl
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Tethered Cord
Effects of Anesthetic Infusion on the Amplitude of Motor Evoked Potential in Pediatrics Undergoing Tethered Spinal Cord Surgeries
The tethered spinal cord is a common pathology in pediatric neurosurgery. Intraoperative neurophysiologic monitoring (IOM) has gained popularity over the past two decades as a clinical discipline that uses neurophysiologic…
- Trial name
- NCT05591001
- Testing
- ketamine and dexmeditomidine combination, Propofol
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Cairo University
Pain, Hypospadias
Dexmedetomidine Infusion and Surgical Pleth Index In Pediatrics
This non-invasive dimensionless score index -SPI-reflects the Patients' sympathetic response to surgical stimulation. Its effectiveness in detecting the balance between nociceptor activation and analgesia was not only reported…
- Trial name
- NCT05727969
- Testing
- Dexmedetomidine, Lactated Ringer, Hypospadias
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Sedation
Use of Clonidine to Prevent Withdrawal Following Prolonged Dexmedetomidine Infusions
The investigators' clinical practice makes use of oral clonidine as a means of transitioning from intravenous dexmedetomidine following prolonged infusions (more than 3-5 days).
- Trial name
- NCT02404077
- Testing
- Clonidine
- Volunteers
- 712 people
- Sponsor
- Joseph D. Tobias