Clinical trials: Diabete Type 1
Diabetes, Type I
Closing the Loop Between Glucose Sensor and Insulin Pump-developing an Algorithm
An open interventional data collection study in order to build a database to close the loop between glucose sensor and insulin pump.
- Trial name
- NCT00541515
- Testing
- continuous glucose sensors and insulin pump
- Where
- Israel
- Volunteers
- 38 people
- Sponsor
- Rabin Medical Center
Diabete Type 1
Strategy For Assessing The Risk Of Type 1 Diabetes In Pediatric Celiac Patients
Celiac disease (CD) and type 1 diabetes mellitus (T1D) are chronic autoimmune disorders that frequently co-occur, largely due to shared genetic susceptibility, particularly HLA-DQ2 and HLA-DQ8 alleles.
- Trial name
- CARES-T1D (NCT07862101)
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- University of Bari
Presymptomatic Diabetes Type 1 (Stage 1), Diabetes Mellitus, Type I
Treatment of Presymptomatic (Stage 1) Type 1 Diabetes Pediatric Patients With Treg Cell Preparations and Anti-CD20 Antibody
The main purpose of the study is to check: Can therapy with a preparation of regulatory cells (Tregs lymphocytes) and/or an anti-CD20 antibody preparation (rituximab) be successfully used in children with pre-diabetes to treat or…
- Conditions
- Presymptomatic Diabetes Type 1 (Stage 1), Diabetes Mellitus, Type I, Diabetes Mellitus, Type 1
- Trial name
- PreTreg (NCT06688331)
- Testing
- ex vivo expanded CD4+CD25+CD127- regulatory T cells (Tregs), Anti-CD20 (rituximab)
- Where
- 9 sites in Poland
- Volunteers
- 150 people
- Sponsor
- PolTREG S.A.
Diabete Type 1, Ketoacidosis, Diabetic
Hemoglobin Levels and Resolution Time of Diabetic Ketoacidosis in Pediatric Patients
This retrospective observational cohort study aims to evaluate the association between hemoglobin levels and the time to resolution of diabetic ketoacidosis (DKA) in pediatric patients.
- Conditions
- Diabete Type 1, Ketoacidosis, Diabetic, Pediatrics, Child
- Trial name
- NCT07377604
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Aydin Adnan Menderes University
Diabetes, Type I
Childhood Diabetes
Purpose of the study: To compare three different regimes for children newly diagnosed with type 1 diabetes: (1) traditional hospital based care, (2) intensive psychological support to the family, and (3) home based family…
- Trial name
- NCT00804232
- Testing
- childhood diabetes
- Where
- 2 sites in Sweden
- Volunteers
- 210 people
- Sponsor
- Vardalinstitutet The Swedish Institute for Health Sciences
Diabetes Mellitus, Type 1, Diabete Type 2
Mapping Diabetes in Quebec: Validating Medico-administrative Algorithms for Type 1 Diabetes, Type 2 Diabetes and LADA
The goal of this observational study is to validate medico-administrative algorithms that classify diabetes phenotypes (Type 1, Type 2, and Latent Autoimmune Diabetes in Adults - LADA) in a population-based cohort in Quebec…
- Conditions
- Diabetes Mellitus, Type 1, Diabete Type 2, Diabetes;Adult Onset, Diabetes, Autoimmune
- Trial name
- VDA (NCT06573905)
- Testing
- no intervention
- Where
- Canada
- Volunteers
- 17,271 people
- Sponsor
- Universite du Quebec en Outaouais
Type 1 Diabetes Mellitus
A Phase III Study to Investigate the Impact of Diamyd in Patients Newly Diagnosed With Type 1 Diabetes (EU)
The purpose of this study is to determine whether Diamyd (rhGAD65 formulated in alum) is effective in preserving the body's own insulin producing capacity in patients recently diagnosed with type 1 diabetes.
- Trial name
- NCT00723411
- Testing
- rhGAD65
- Where
- 70 sites in Finland, France and 7 more
- Volunteers
- 334 people
- Sponsor
- Diamyd Therapeutics AB
Type 1 Diabetes
Incretin-based Therapy in Early Diagnosed Type 1 Diabetes
The main objective of the trial is to study whether daily treatment with liraglutide improves insulin secretion and reduces the requirement of exogenous insulin, and whether liraglutide treatment is tolerable and safe in subjects…
- Trial name
- NCT02908087
- Testing
- Victoza® (liraglutide)
- Where
- 4 sites in Finland, Sweden
- Volunteers
- 13 people
- Sponsor
- University of Oulu
Diabetes Mellitus, Type 1
GAD-Alum (Diamyd) Administered Into Lymph Nodes in Combination With Vitamin D in Type 1 Diabetes (DIAGNODE-1)
The objectives of the main study is to: Evaluate the safety of giving GAD-Alum (Glutamic acid decarboxylase) (Diamyd) directly into lymph glands in combination with an oral vitamin D regimen Evaluate how the above mentioned…
- Trial name
- DIAGNODE (NCT02352974)
- Testing
- GAD-Alum, Vitamin D
- Where
- Sweden
- Volunteers
- 12 people
- Sponsor
- Johnny Ludvigsson
Diabetes Mellitus, Type 1
Young With Diabetes Type 1 - Test of an mHealth App
A multicenter randomized controlled trial testing the app "Young with Diabetes"
- Trial name
- NCT02632383
- Testing
- Young with Diabetes - app
- Where
- 6 sites in Denmark
- Volunteers
- 140 people
- Sponsor
- Nordsjaellands Hospital
Diabetes Type 1
Impact of the Mylife CamAPS FX System With the DEXCOM G6 Sensor on T1D Patients in France
This is a non-interventional, longitudinal, prospective, multicenter, post market-registration and national study conducted in France.
- Trial name
- EPICAM-G6 (NCT07048795)
- Testing
- No Intervention: Observational Cohort
- Where
- 22 sites in France
- Volunteers
- 125 people
- Sponsor
- mylife Diabetes Care AG
Diabetes Mellitus
Role of TMEM219 Marker in Type 1 Diabetes
Type 1 diabetes (T1D) is a chronic metabolic disease characterized by autoimmune destruction of β cells of the insulin producing pancreatic islets.
- Trial name
- NPOD (NCT03794739)
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Milan
Diabetes, Type I
Diabetes Type 1, Treatment Study Atacand/Placebo After Kidney Biopsy
The type 1 diabetes patients who were still normoalbuminuric and normotensive, after 17 years duration and a second research kidney biopsy, could enter the double blind treatment study of Atacand or Placebo.
- Trial name
- NCT00328302
- Testing
- Candesartan
- Where
- Sweden
- Volunteers
- 13 people
- Sponsor
- Karolinska University Hospital
Diabete Type 1, Educational Videos
Interactive Educational Video for Paediatric Type 1 Diabetes
The primary aim of this study is to evaluate the effectiveness of an interactive educational video (Luca's Journey: Managing Type 1 Diabetes) delivered in addition to the standard educational programme, in improving metabolic…
- Trial name
- Intedu (NCT07639307)
- Testing
- Interactive Educational Video (Luca's Journey: Managing Type 1 Diabetes), Traditional Face-to-Face Education
- Volunteers
- 110 people
- Sponsor
- G. d'Annunzio University
Diabetes, Diabetes Care
Changing Outpatient Diabetes Care With Remote-Patient-Monitoring: A Real World Evidence Study With Pre-Post Comparison
The goal of this observational pre-post study is to evaluate a remote-patient-monitoring-system (RPM-system) integrated within an electronic health record (EHR) system in a real world cohort of approximately 12.000 people with…
- Conditions
- Diabetes, Diabetes Care, Diabetes Type 1, Diabetes Type 2
- Trial name
- NCT07617519
- Testing
- Remote-Patient-Monitoring (RPM)
- Where
- Denmark
- Volunteers
- 12,000 people
- Sponsor
- Steno Diabetes Center Copenhagen
Diabetes Mellitus, Type 1
Comparison With Observational Methods and Performance Assessment From Real-life Experience of Closed-Loop Insulin Delivery Systems
This study aims to compare glycemic control obtained under closed loop depending on the system : Smartguard (Medtronic 780) versus Control IQ (Tandem) in patients with diabetes type 1.
- Trial name
- COMPARE-CLIDS (NCT05932966)
- Testing
- Insulin closed-loop delivery system
- Where
- France
- Volunteers
- 317 people
- Sponsor
- Centre Hospitalier Sud Francilien
Diabetes, Diabetes Mellitus, Type 1
Safety and Efficacy of NovoLog vs. Humalog in Insulin Pumps in Children and Adolescents
This trial is conducted in the United States of America (USA). It is demonstrated that intensive insulin therapy resulting in good glycaemic control can reduce or delay the incidence of complications secondary to Type 1 Diabetes.
- Trial name
- NCT00097071
- Testing
- insulin lispro, insulin aspart
- Where
- 52 sites in United States
- Volunteers
- 299 people
- Sponsor
- Novo Nordisk A/S
Diabetes in Children, Diabetes Type 1
Intelligent Care Platform - Quasi-Experimental Trial
This study will measure the implementation and effectiveness of an intervention, the use of a digital health tool, Haibu Diabetes, for the management of pediatric type 1 diabetes (T1D), on clinical outcomes.
- Trial name
- UBColumbia (NCT07712809)
- Testing
- Digital Diabetes Care Platform
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University of British Columbia
Diabetes Mellitus, Type 1
DIABGAD - Trial to Preserve Insulin Secretion in Type 1 Diabetes Using GAD-Alum (Diamyd) in Combination With Vitamin D and Ibuprofen
The objectives of this study is to evaluate the safety and influence of treatment with GAD-Alum (Diamyd) combined with Vitamin D and Ibuprofen on preservation of residual insulin secretion in recently diagnosed Type 1 Diabetes…
- Trial name
- NCT01785108
- Testing
- GAD-Alum (Diamyd) 20 µg, GAD-Alum (Diamyd) 20 µg X 2, Vitamin D
- Where
- 10 sites in Sweden
- Volunteers
- 60 people
- Sponsor
- Johnny Ludvigsson
Diabete Type 1
Cardiopulmonary Fitness and Health-Related Quality of Life in Children and Adolescents With Type 1 Diabetes (FIT-T1D)
Children and adolescents with type 1 diabetes (T1D) are at risk of a sedentary lifestyle, as this chronic disease may lead patients into a vicious cycle of deconditioning, resulting in reduced physical activity levels and…
- Trial name
- FIT-T1D (NCT07728435)
- Where
- France
- Volunteers
- 214 people
- Sponsor
- Institut Saint Pierre