Clinical trials: Diagnoses Diseases
Syncope
The Diagnostic Performance of Tilt Test in Athletes
In the present study the investigators evaluate the sensitivity and specificity of passive tilt test in athletes, as well as their haemodynamic responses and autonomic nervous system activity during head-up tilt.
- Trial name
- NCT02316860
- Testing
- Passive tilt test
- Where
- Greece
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Autism Spectrum Disorder, Developmental Disorder
Children's Autism Metabolome Project
Development and Clinical Evaluation of the Stemina Metabolic Biomarker-Based Test to Diagnose Autism Spectrum Disorder in Early Childhood.
- Trial name
- CAMP-01 (NCT02548442)
- Where
- 8 sites in United States
- Volunteers
- 1,102 people, healthy volunteers welcome
- Sponsor
- Stemina Biomarker Discovery, Inc.
Neurogenetic Diseases
Advancing Neurogenetic Diagnoses Through Long-Read Sequencing
Nucleotide repeats emerge as one of the most prolific classes of genetic variations. They have the propensity to in-crease in length across generations, and have been implicated in at least 65 known neurological/…
- Trial name
- NRGEN-NGS3 (NCT07665554)
- Testing
- Skin biopsy, blood sampling
- Where
- 2 sites in France
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Asperger Syndrome, Autism
Evaluation of the French Version of Screening Questionnaires for Autism and Asperger Syndrome: AQ, EQ and SQ
Autism is considered as an invading disorder of the development. Asperger Syndrome (AS) is a particular form of autism and is difficult to diagnose.
- Trial name
- NCT00505830
- Testing
- questionnaires
- Where
- France
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Groupe Francais d'Epidemiologie Psychiatrique
Quality of Life, Injection Site Reaction
Simultaneous mRNA COVID-19 and IIV4 Vaccination Study
This study is a prospective, randomized clinical trial. During this study, participants will be randomly assigned to receive quadrivalent inactivated influenza vaccine (IIV4) and mRNA COVID-19 vaccine either simultaneously or…
- Conditions
- Quality of Life, Injection Site Reaction, Adverse Drug Event, Systemic Reaction
- Trial name
- NCT05028361
- Testing
- mRNA COVID-19, IIV4
- Where
- 3 sites in United States
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Duke University
Oral Cancer, Oral Squamous Cell Carcinoma
Salivary Expression of SOX7 in Oral Squamous Cell Carcinoma: Diagnostic Accuracy Study
The study will include patients with oral cancer and healthy controls of both sexes. Subjects having any systemic diseases or other types of cancer will be excluded.
- Trial name
- NCT06031337
- Testing
- ELISA
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Acute Febrile Illness
Clinical Study of Transcriptome-based Diagnostic Biomarker for Acute Febrile Illness
Acute febrile illness is the main cause of outpatient visits，and bacterial and viral infections remains the most common cause. The diagnosis of infection is still based on symptoms and traditional techniques, resulting in overuse…
- Trial name
- NCT06552975
- Testing
- Infection
- Where
- China
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Autism Spectrum Disorder, Other Neurodevelopmental Disorder
Early Assessment of Autism Through Smart Tablet Gameplay
The primary aim of this study is to compare the diagnostic accuracy of an iPad application (Play.Care assessment) with the current clinical "gold standard" diagnosis for diagnosis of Autism Spectrum Disorder (ASD) in children.
- Trial name
- NCT03438994
- Testing
- Play.Care
- Where
- 2 sites in Sweden, United Kingdom
- Volunteers
- 779 people, healthy volunteers welcome
- Sponsor
- University of Strathclyde
COVID-19
Bioaerosol Sampling Device (BSD) Clinical Study
The goal of this clinical trial is to learn about the bioaerosol sampling device (BSD) and how it can sample patient bioaerosols (breath) and patient's nares for the detection of COVID-19 viral particles in patients seeking to be…
- Trial name
- NCT06047067
- Where
- 6 sites in United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Cantor BioConnect, Inc.
Toxoplasmosis, Toxoplasma Infections
Diagnosis of Toxoplasma Gondii Infection by Exploration of Cellular Immunity (TOXCELL)
Toxoplasmosis is a parasitic disease caused by Toxoplasma gondii and transmitted to humans through the consumption of raw or undercooked infected meat and / or by poorly washed vegetables.
- Conditions
- Toxoplasmosis, Toxoplasma Infections, Toxoplasmosis, Congenital, Toxoplasmosis Recurrent
- Trial name
- TOXCELL (NCT04825600)
- Testing
- anti-Toxoplasma gondii IgG and IgM dosage, cellular test
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Acute Coronary Syndrome
Potential Diagnostic and Prognostic Value of microRNAs for the Patients of Acute Coronary Syndrome
The purpose of this study is to evaluate the potential diagnostic and prognosis value of circulating microRNAs compared with cTnI for suspected ACS patients at the emergency department (ED) and intensive care unit (ICU).
- Trial name
- NCT02755207
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Short Stature
The Role of Igf-1 Generation Test in Diagnosis and Treatment of Short Stature
The purpose of the study is to evaluate the predictive value of IGF-1 generation test for growth velocity during GH treatment for 12 months.
- Trial name
- NCT01970800
- Testing
- Growth Hormone
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Maimonides Medical Center
Tuberculosis, Pulmonary
Integrated Discovery and Development of Innovative TB Diagnostics
The long term goal of this project is to provide information critical to the development and use of a low-cost, point-of-care, rapid, simple, and highly accurate diagnostic tool that can help clinicians make a microbiological…
- Trial name
- (CETR) (NCT06624501)
- Testing
- Observational cohort study
- Volunteers
- 1,450 people, healthy volunteers welcome
- Sponsor
- Harvard University Faculty of Medicine
Asthma
A Trial Evaluating Novel Technologies for the Diagnosis of Asthma The LUNG-TECH Trial
This trial aims to evaluate novel diagnostic technologies for asthma in 3 different pathways providing the necessary evidence-base to allow adoption into clinical practice: Pathway 1 evaluates whether the technology can…
- Trial name
- LUNG-Tech (NCT05819944)
- Where
- United Kingdom
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- Portsmouth Hospitals NHS Trust
Neurodevelopmental Disorder (Diagnosis)
Virtual Reality Headset as an Alternative Tool for Reducing Dental Anxiety
The aim of this study is to investigate whether the use of virtual reality (VR) headsets can have a positive effect on dental fear during dental procedures and stress induced by the dental environment.
- Trial name
- NCT07667023
- Testing
- Virtual reality headset, standard dental care
- Where
- Hungary
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Cystic Fibrosis
Small Circulating RNA as Molecular Markers of Lung Disease in Cystic Fibrosis
The aim of our study is to assess miRNAs expression profiles in the circuling blood of patients with cystic fibrosis and highlight "signatures" that could reflect the pulmonary status of patients
- Trial name
- MIRDIAMUCO (NCT02992080)
- Testing
- miRNAs isolation from blood samples of patients and control
- Where
- 2 sites in France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Diagnosis
Echocardiographic Standards and Sub-Saharian Africans (SSA) Migrants' in New Aquitaine Region
Standards Echocardiographic have been defined mainly on caucasian or Asian populations. In the EchoNoRMAL study the criteria for African populations were based solely on data from 198 subjects.
- Trial name
- NEMANA (NCT04865068)
- Testing
- Echocardiography measures on SSA participants
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
SARS-CoV2 Infection, COVID-19
BinaxNOW for Evaluating Children for Infection With SARS-CoV-2 (COVID-19)
This is a study of the BinaxNOW Covid-19 Ag Card as a method to rapidly identify SARS-CoV-2 infection in asymptomatic children, teachers, and other school staff for exclusion.
- Trial name
- NCT05087524
- Testing
- BinaxNOW Ag Card
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Primary Immunodeficiency
Diagnostic Immunization With Rabies Vaccine in Patients With PID
The purpose of this study is to evaluate diagnostic immunization protocol of rabies vaccine for diagnosis the patients with primary immunodeficiency disorders and study humoral and cellular immune response to rabies vaccine in…
- Trial name
- NCT02490956
- Testing
- Verorab® (PVRV; Purified Vero Cell Vaccine)
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Cardiovascular Diseases, Hypertrophic Cardiomyopathy (HCM)
AI-enabled Screening and Diagnosis of Cardiomyopathies Using Coronary CTA
The goal of this observational and diagnostic study is to develop and validate an artificial intelligence assisted approach for coronary computer tomography angiography-(CCTA)-based screening and diagnosis of cardiomyopathies in…
- Conditions
- Cardiovascular Diseases, Hypertrophic Cardiomyopathy (HCM), Dilated Cardiomyopathy (DCM), Restrictive Cardiomyopathy
- Trial name
- Atlantis (NCT06748261)
- Testing
- CCTAI model
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital