Clinical trials: Diarrhoea;Acute
Acute Gastroenteritis
Efficacy of Gelatin Tannate in Treatment Acute Gastroenteritis in Children.
Gelatin tannate possesses astringent, antibacterial, and anti-inflammatory properties. It is increasingly being marketed as an antidiarrheal drug.
- Trial name
- NCT02280759
- Testing
- Gelatin Tannate
- Where
- Poland
- Volunteers
- 72 people
- Sponsor
- Medical University of Warsaw
Diarrhoea;Acute, Diarrhea, Infantile
Efficiency and Safety of Zinc Sulphate to Reduce the Duration of Acute Diarrheal Disease Between 6 and 59 Months of Age
This study evaluates the effect of zinc over the duration, severity and relapse of acute diarrheic disease, in children between 6 and 59 months of age.
- Trial name
- ESZnDiarrhea (NCT04061538)
- Testing
- zinc sulfate
- Where
- 9 sites in Mexico
- Volunteers
- 529 people
- Sponsor
- Instituto Nacional de Salud Publica, Mexico
Acute Diarrhea
Effects of Probiotics and/or Prebiotics on the Duration of Diarrhea and Hospitalization in Children
Acute diarrhea continues to be a major cause of childhood morbidity and mortality in developed and developing countries. Prevention and treatment of dehydration are the mainstays of therapy.
- Trial name
- PROBAGE (NCT01927094)
- Testing
- Probiotic, ORS
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 1,280 people
- Sponsor
- Eskisehir Osmangazi University
Acute Diarrhea, Acute Respiratory Infection
Improving Nighttime Access to Care and Treatment (Part 2)
Children in resource-limited settings who develop illness at night are often isolated from pre-emergency care, resulting in progression to an emergency because families are forced to wait until morning to seek care.
- Conditions
- Acute Diarrhea, Acute Respiratory Infection, Acute Febrile Illness
- Trial name
- INACT2 (NCT03943654)
- Testing
- MotoMeds Healthline- illness assessment and treatment recommendation for non-emergent cases by telephone
- Where
- Haiti
- Volunteers
- 391 people
- Sponsor
- University of Florida
Pneumonia, Diarrhea
Vitamin A and Zinc: Prevention of Pneumonia (VAZPOP) Study
Children with malnutrition are often low in some nutrients, like zinc or vitamin A, that could help them fight off infections like pneumonia.
- Conditions
- Pneumonia, Diarrhea, Acute Upper Respiratory Tract Infections
- Trial name
- NCT00228254
- Testing
- Zinc (12.5 mg/day), vitamin A 10,000 IU per week
- Where
- 2 sites in United States, Ecuador
- Volunteers
- 2,582 people, healthy volunteers welcome
- Sponsor
- Tufts University
Acute Leukemias of Ambiguous Lineage, Bacterial Infection
Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation
This randomized phase III trial studies how well levofloxacin works in preventing infection in young patients with acute leukemia receiving chemotherapy or undergoing stem cell transplant.
- Conditions
- Acute Leukemias of Ambiguous Lineage, Bacterial Infection, Diarrhea, Fungal Infection
- Trial name
- NCT01371656
- Testing
- levofloxacin
- Where
- 84 sites in United States, Canada
- Volunteers
- 624 people
- Sponsor
- Children's Oncology Group
Diarrhea, Children
Effectiveness of Oral Rehydration Therapy Supplemented With Zinc in the Management of Diarrhea Acute
Acute diarrhea is the third cause of infant mortality in the world causing 15% of all deaths in children under 5 years and is responsible for nearly 1.4 million deaths in developing countries.
- Trial name
- NCT02601742
- Testing
- Zinc group
- Volunteers
- 350 people
- Sponsor
- Hospital General Naval de Alta Especialidad - Escuela Medico Naval
Acute Watery Diarrhea, Acute Watery Diarrhoea
Comparison of Two Probiotics for Reducing Diarrhea Frequency in Children Aged 6-24 Months
Clinical Trial Summary The goal of this clinical trial is to compare the effectiveness of Saccharomyces boulardii CNCM I-745 and multi-strain Bacillus clausii in reducing the frequency of acute watery diarrhea in children aged 6…
- Conditions
- Acute Watery Diarrhea, Acute Watery Diarrhoea, Diarrhea
- Trial name
- NCT07921836
- Testing
- Saccharomyces boulardii CNCM I-745, Bacillus clausii (O/C, SIN, N/R, T)
- Volunteers
- 88 people
- Sponsor
- King Edward Medical University
Radiation-induced Diarrhoea in Prostate and Rectal Cancer
Radiation-induced Diarrhoea During Curative EBRT of Prostate and Rectal Cancer
Approx. 80% of patients with prostate and rectal cancer who receive radiation therapy (RT) experience acute radiation-induced diarrhea (RID).
- Trial name
- PRECANU (NCT05684432)
- Testing
- No intervention
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Aalborg University Hospital
Acute Gastroenteritis, Diarrhea
Surveillance Study of Acute Gastroenteritis in Hospitalized Children in Rural Area in Lebanon
Acute gastroenteritis is a common cause of hospitalization in children with significant socioeconomic burden on the health community, we will follow in this observational and analytical study the admitted cases of acute…
- Conditions
- Acute Gastroenteritis, Diarrhea, Rotavirus
- Trial name
- SAGE (NCT02177799)
- Where
- Lebanon
- Volunteers
- 150 people
- Sponsor
- Shaikh Ragheb Harb Hospital
Malaria, Diarrhea
Liberia National Community Health Assistant (NCHA) Program and Under-five Mortality
Last Mile Health (LMH) has partnered with the Liberian Ministry of Health (MOH) to support the design and implementation of the National Community Health Assistant Program (NCHAP).
- Conditions
- Malaria, Diarrhea, Acute Respiratory Infection, Malnutrition, Child
- Trial name
- NCT05123378
- Testing
- Liberia National Community Health Assistant Program
- Where
- Liberia
- Volunteers
- 23,702 people, healthy volunteers welcome
- Sponsor
- Last Mile Health
Acute Diarrhoea
Acceptability and Effectiveness of Household Water Treatment in Reducing Diarrhea Among Under Five Children
The Millenium development goals (MDGs) call for reducing by half the proportion of people without sustainable access to safe drinking water.
- Trial name
- NCT01376440
- Testing
- household water treatment
- Where
- Ethiopia
- Volunteers
- 845 people
- Sponsor
- Haramaya Unversity
Gastroenteritis
Efficacy of Two Probiotic Preparations in Children With Acute Diarrhoea
The purpose of this study is to determine which of two different preparations of probiotics is effective in the treatment of acute viral diarrhoea in children.
- Trial name
- NCT02080130
- Testing
- Saccharomyces boulardii, Probiotics combination
- Where
- Mexico
- Sponsor
- Sinaloa Pediatric Hospital
Diarrhea
Safety, Efficacy and Cost-effectiveness of Racecadotril in Children With Acute Diarrhea in Mexico
Rationale: Acute diarrhea (AD) is still a significant morbidity-mortality problem worldwide. Although oral rehydration therapy is the cornerstone, its anti-diarrheal effect is a controversial subject.
- Trial name
- Raceca-Mex (NCT01153854)
- Testing
- Racecadotril
- Where
- Mexico
- Volunteers
- 454 people
- Sponsor
- National Institute of Pediatrics, Mexico
Acute Infectious Diarrhoea in Children
Isoleucine Added ORS in Children With Diarrhoea
Efforts are continuing to improve the efficacy of oral rehydration solution in terms of reducing the severity (stool volume) and duration of diarrhoea (enhancement of recovery).
- Trial name
- NCT01034228
- Testing
- ORS + Isoleucine, ORS without Isoleucine
- Where
- Bangladesh
- Volunteers
- 50 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh