Clinical trials: Digestive Disorders
Childhood Obesity, Overweight and Obesity
Childhood Obesity - Prevention of Diabetes Through Changed Eating Patterns
The main purpose of the present study is to perform a 10 weeks dietary intervention study with a follow-up for 52 weeks in children from 7-14 years of age with overweight or obesity.
- Conditions
- Childhood Obesity, Overweight and Obesity, Adolescent Obesity, Adolescent Overweight
- Trial name
- COPE (NCT04522921)
- Testing
- Diet with a higher amount of protein (25E% per day), Increased follow-up contact after the 10-week intervention, Diet with a lower amount of protein (15E% per day)
- Where
- 2 sites in Denmark
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Blood Clots, Infection and Inflammatory Reaction
Cobas® Lumira Collection of Venous and Capillary Blood Samples for the Research, Optimization and Calibration of New Diagnostic Devices
This study is a blood sample collection study, collecting venous and capillary blood samples from adult patients in the UK, with a range of health conditions.
- Conditions
- Blood Clots, Infection and Inflammatory Reaction, Heart Disease, Kidney Disease
- Trial name
- EVOLVE (NCT07378514)
- Testing
- Blood samples are obtained and pseudonymized, prior to use for the development, optimization and calibration of diagnostic tests
- Volunteers
- 30,000 people
- Sponsor
- LumiraDx UK Limited
Pancreatic Cancer
Changes in Muscle Tissue in Patients With Pancreatic Cancer
RATIONALE: Measuring changes in muscle tissue in patients with cancer may help doctors predict how well patients will respond to treatment, and may help the study of cancer in the future.
- Trial name
- NCT00369460
- Testing
- physiologic testing
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Case Comprehensive Cancer Center
Gastric Cancer
A Retrospective Validations Microsatellite Instability (MSI) Testing v Mismatch Repair (MMR) in Gastric Adenocarcinoma
To compare the Idylla microsatellite instability test versus mismatch repair immunohistochemistry (IHC) in gastric adenocarcinoma.
- Trial name
- NCT04232020
- Testing
- Mismatch repair
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Royal Cornwall Hospitals Trust
Hemorrhoids
The Relationship Between Hemorrhoids and Smartphone Use in the Lavatory
The objective of this study is to examine the relationship between hemorrhoids, a common complaint, and the use of smartphones, also a common feature of modern life, in the lavatory.
- Trial name
- NCT03444389
- Where
- Turkey (Türkiye)
- Volunteers
- 1,798 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Appendicitis
Laparoscopic Versus Open Appendectomy? Let the Patient Decide
This protocol examines choice where it pertains to choosing between two standard methods for appendectomy, laparoscopic or open procedures, and the affect that "cost" of the appendectomy has upon choice.
- Trial name
- NCT01738750
- Testing
- Cost Information Included
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Utah
Cystic Fibrosis
Use of Capnography for the Follow-up of Cystic Fibrosis Children
The respiratory system involvement in cystic fibrosis(CF) influences the prognosis and course of disease. Respiratory assessment is based on spirometry, but its main parameter, the maximal expiratory volume in the first second…
- Trial name
- MUCOCAP (NCT04814797)
- Testing
- Capnography data included in Lung Clearance Index measurement
- Where
- 2 sites in France
- Volunteers
- 76 people
- Sponsor
- Central Hospital, Nancy, France
Rectal Cancer
Intraoperative Angiography Using ICG in Rectal Cancer Patients to Prevent Anastamotic Leak After Laparoscopic Anterior Resection of the Rectum
The study enrols patients with operative rectal cancer qualified for laparoscopic anterior resection. Patients are given first dose of indocyanine green iv intraoperatively (ICG) before choosing the appropriate site of the…
- Trial name
- NCT05263336
- Testing
- Verdye Green
- Where
- Poland
- Volunteers
- 180 people
- Sponsor
- Jagiellonian University
Hepatitis B, Immunization; Infection
Hepatitis B Birth Dose for Newborns
With 2.5% prevalence in general population, Pakistan is an intermediate endemicity country for hepatitis B. However, wide disparity exists across the country as disease prevalence in general population soars as high as 14% in…
- Trial name
- HepB-BirD (NCT04870021)
- Testing
- recombinant hepatitis B vaccine ENGERIX 10 micrograms (µ gm),, Short text messages and calls to parents for compliance to routine immunization schedule
- Where
- Pakistan
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Quaid-e-Azam University
Feeding Disorders
CHAMP For the Feeder: Tube Feeding Study
Single site evidence-based implementation of a mHealth application for remote patient monitoring for pediatric patients ready to wean from tube feedings (TFs).
- Trial name
- NCT06052891
- Testing
- CHAMP Application
- Where
- United States
- Volunteers
- 245 people
- Sponsor
- Lori Erickson
Cystic Fibrosis
Efficacy of an Infrared Visualization Technique for the Identification of the Peripheral Venous Access Site in Patients With Cystic Fibrosis Aged 12 Years and Older
Cystic fibrosis is a rare chronic genetic disease that mainly affects the respiratory tract and the digestive system. Their management includes multi-year intravenous antibiotic treatments and repeated venous sampling.
- Trial name
- MUCOVEINE (NCT04226118)
- Testing
- Vein Illumintion System device
- Where
- 6 sites in France
- Volunteers
- 271 people
- Sponsor
- Hospices Civils de Lyon
Alcoholic Liver Disease
Gut Mycobiome Profile in Alcoholic Liver Disease.
The fecal mycobiome, which refers to the community of fungi that resides in the human gut, is an important component of the gut microbiome.
- Trial name
- NCT05793190
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Anorexia Nervosa
Virtual Reality Exposure to Reduce Food Related Anxiety in Anorexia Nervosa
Exposure to food stimuli often elicit aversive emotions in patients with anorexia nervosa, which can perpetuate eating-related avoidance.
- Trial name
- NCT06795555
- Testing
- Virtual reality food exposure, Virtual Reality Nature Exposure
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Padova
Appendicitis, Pain, Postoperative
Narcotic vs. Non-narcotic Pain Regimens After Pediatric Appendectomy
There is concern that pain prescription after outpatient pediatric surgical procedures is excessive and is in excess of patient need.
- Trial name
- NCT03528343
- Testing
- Non-narcotic pain control
- Where
- United States
- Sponsor
- University of Utah
Chronic Hepatitis B
Efficacy Study of Prednisone Priming to Treat Asian Chronic Hepatitis B Patients
Patients with chronic hepatitis B constantly produce the virus in the body. The disease of chronic hepatitis B is the body responding to the virus. Use of steroids can adjust this response.
- Trial name
- NCT00715715
- Testing
- Prednisone Priming
- Where
- United States
- Sponsor
- Maimonides Medical Center
Hepatocellular Carcinoma
Establishment of a Tissue Registry for Hepatocellular Carcinoma Specimens
The goal of the study is to establish a cancer registry to facilitate research and assist in the identification of additional risk factors for hepatocellular carcinoma. The main objectives are: 1.
- Trial name
- TIR-HCC (NCT05935189)
- Where
- Armenia
- Volunteers
- 500 people
- Sponsor
- Nikomed Medical Center
Stress Ulcers, Stress-related Mucosal Disease (SRMD)
China Survey of Stress Ulcer Bleeding in Critically Ill Neurosurgical Patients
Stress ulcers or stress-related mucosal disease (SRMD) is defined as "acute superficial inflammation lesions of the gastric mucosa induced when an individual is subject to abnormally elevated physiologic demands."[1] Studies have…
- Trial name
- SUP (NCT02316990)
- Where
- 11 sites in China
- Volunteers
- 1,416 people
- Sponsor
- AstraZeneca
Biliary Atresia, Kasai Portoenterostomy Status
Clinical Study About the Role of COX-2 Inhibitor in Liver Cirrhosis With Biliary Atresia
In this clinical study, meloxicam will be used to the patients who are older than 2 years and underwent Kasai portoenterostomy to treat their biliary atresia before.
- Trial name
- NCT02298218
- Testing
- Meloxicam
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Ulcerative Colitis
Tacrolimus (FK506) Study in Moderate to Severe Refractory Ulcerative Colitis Patients
This study consists of a 2-week placebo-controlled double-blind inter-group efficacy study in moderate to severe refractory ulcerative colitis (UC) patients followed by a maximum of 12-week open-label efficacy and safety study in…
- Trial name
- NCT00347048
- Testing
- tacrolimus
- Where
- 6 sites in Japan
- Volunteers
- 62 people
- Sponsor
- Astellas Pharma Inc
Gastric Cancer
Surgery for Obstructed Gastric Carcinoma
The goal of this clinical trial is to find the best treatment for obstructed gastric carcinoma in gastric cancer patients. It will include all patients with obstructed gastric cancer with different ages and sex who consented to…
- Trial name
- NCT07435025
- Testing
- palliative gastric resection, palliative bypass
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- Zagazig University
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