Clinical trials: Digestive System Neoplasms
Esophageal Cancer
Quality-of-Life Assessment of Patients Who Have Cancer of the Esophagus
RATIONALE: Questionnaires that measure quality of life may improve the ability to plan treatment for patients who have cancer of the esophagus.
- Trial name
- NCT00003321
- Testing
- psychosocial assessment and care, quality-of-life assessment
- Where
- 10 sites in Australia, France and 6 more
- Volunteers
- 370 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Esophageal Cancer
Anlotinib for Esophageal Cancer (AFEC)
The purpose of this study is to observe and explore the effect of single or combined treatment of arotinib on the survival and prognosis of patients with advanced esophageal cancer in the real world, and to summarize the…
- Trial name
- NCT04966611
- Testing
- Anlotinib
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Anyang Tumor Hospital
Hepatocellular Carcinoma (HCC)
Precision Recurrence Risk Assessment in Early-stage Hepatocellular Carcinoma
This retrospective observational study aims to evaluate whether artificial intelligence (AI) models can predict aggressive recurrence in patients who underwent liver resection for early-stage hepatocellular carcinoma (HCC).
- Trial name
- NCT07030842
- Testing
- liver resection
- Where
- China
- Volunteers
- 579 people
- Sponsor
- Tongji Hospital
Hepatitis B, Hepatocellular Carcinoma
Modified Process Hepatitis B Vaccine in Healthy Neonates (V232-056)
Hepatitis B Vaccine [Recombinant] is a well-established vaccine which has been used extensively, worldwide since its initial licensure in 1986.
- Trial name
- NCT00322361
- Testing
- Comparator: RECOMBIVAX HB™, Comparator: Modified process Hepatitis B Vaccine
- Volunteers
- 566 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Peritoneal Neoplasms, Neoplasm Metastasis
HIPEC For Peritoneal Surface Malignancies Including Carcinomatosis or Sarcomatosis - Data Registry
In this registry study the investigators will collect data about patients' disease, treatment, and response to treatment to include in both our local and national databases.
- Conditions
- Peritoneal Neoplasms, Neoplasm Metastasis, Adenocarcinoma, Sarcoma
- Trial name
- NCT02082886
- Where
- 2 sites in United States
- Volunteers
- 193 people
- Sponsor
- Edward-Elmhurst Health System
Gastric Ulcer, Duodenal Ulcer
Cytokine Gene Polymorphisms in Gastric Diseases
Recently, cytokine polymorphisms are considered to play an important role in the pathogenesis of peptic ulcer and gastric cancer.
- Conditions
- Gastric Ulcer, Duodenal Ulcer, Gastric Cancer
- Trial name
- NCT00197470
- Testing
- IL-1, TNF-alpha, Il-10
- Where
- Japan
- Sponsor
- Hamamatsu University
Gastric Cancer Stage IV
Conversion Surgery After Target Therapy or Immunotherapy in Stage IV Gastric Cancer
In this retrospective study, investigators conducted a comprehensive investigation of the factors influencing postoperative prognosis in patients with stage IV gastric cancer undergoing conversion surgery.
- Trial name
- NCT07009600
- Testing
- immune check point inhibitors (PD-1 inhibitors), target therapy (trastuzumab)
- Volunteers
- 124 people
- Sponsor
- Samsung Medical Center
Colorectal Cancer (CRC), Pancreatic Cancer
Expanded Access Program (EAP) Designed to Provide Access to Botensilimab and Balstilimab Before Regulatory Approval
This is an expanded access program (EAP) designed to provide access to Botensilimab and Balstilimab prior to drug registration by the applicable local regulatory agency.
- Conditions
- Colorectal Cancer (CRC), Pancreatic Cancer, Non-Small Cell Lung Cancer (NSCLC), Hepatocellular Carcinoma (HCC)
- Trial name
- NCT06751524
- Testing
- Botensilimab, Balstililmab
- Sponsor
- Agenus Inc.
Chronic Pancreatitis, Exocrine Pancreas Carcinoma
Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study
This clinical trial collects blood, saliva, urine, or stool samples to help identify possible genetic mutations that may increase a person's chance at developing pancreatic cancer.
- Conditions
- Chronic Pancreatitis, Exocrine Pancreas Carcinoma, Recurrent Acute Pancreatitis
- Trial name
- NCT06651580
- Testing
- Biospecimen Collection, Quality-of-Life Assessment, Questionnaire Administration
- Where
- 26 sites in United States, Australia and 2 more
- Volunteers
- 1,600 people
- Sponsor
- M.D. Anderson Cancer Center
Pancreatic Endocrine Neoplasms
An Analysis of Presentation and Outcome Following Treatment of Pancreatic Endocrine Neoplasms
A single institutional study of Pancreatic Endocrine Neoplasms over 18 years.
- Trial name
- NCT02400996
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical College and Hospital Kolkata
Colorectal Neoplasms, Stomach Neoplasms
Proteomic Analysis of HLA Complex in Solid Cancers: Breast, Ovary, Colon, Rectum, Stomach, and Pancreas
The purpose of this study is to evaluate the presence of proteins in solid tumors which may lead to an immune response
- Conditions
- Colorectal Neoplasms, Stomach Neoplasms, Pancreatic Neoplasms, Breast Neoplasms
- Trial name
- NCT00419627
- Where
- Israel
- Volunteers
- 160 people
- Sponsor
- Hillel Yaffe Medical Center
Incidence of Cholangiocarcinoma on Choledochal Cysts, Postoperative Complications in Choledochal Cysts
Analysis of the Incidence of Cholangiocarcinoma on Choledochal Cyst in a Western Center
Choledochal cysts are congenital cystic dilatations of the intra and/or extrahepatic bile duct. They have been considered a rare entity of the child population.
- Conditions
- Incidence of Cholangiocarcinoma on Choledochal Cysts, Postoperative Complications in Choledochal Cysts, Choledochal Cyst Monitoring
- Trial name
- QuiCo (NCT05404503)
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- María Teresa Moreno Asencio
Colectomy, Appendicitis
Colonic Resections in Patients With Suspected Appendicitis
Although many reports have been published on colonic resections in patients with suspected appendicitis and the diseases that cause the decision to resect the colon have been identified and their proper treatments have been…
- Trial name
- NCT00888888
- Testing
- Right hemicolectomy with or without primary anastomosis
- Where
- Chile
- Volunteers
- 87 people
- Sponsor
- Cirujanos la Serena
Choledochal Cyst
Clinical Features and Prognosis of Asymptomatic Biliary Dilatation
This study is a multicenter, ambidirectional cohort study aiming to consecutively recruit asymptomatic biliary dilation patients incidentally discovered by imaging from 25 medical centers across China.
- Trial name
- NCT07028164
- Where
- China
- Volunteers
- 1,008 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Gastrointestinal Bleeding, Gastrointestinal Neoplasms
A Disposable Endoscopic Closing Device Used for the Closure of Gastrointestinal Tissue
This clinical trial employs a prospective, multicenter, randomized, single-blind, parallel-controlled, non-inferiority design with a positive comparator device.
- Trial name
- NCT07727564
- Testing
- disposable endoscopic closing device, metal clips, or metal clips in combination with nylon loops
- Volunteers
- 60 people
- Sponsor
- Jiangsu Vedkang Medical Science and Technology Co., Ltd
Gastric Cancer, Colorectal Cancer
Status of Management of Surgery in Beijing During COVID-19
This is a multi-centered, retrospective, observational study aimed at observing the current status of the management of gastrointestinal surgery during the COVID-19 pandemic, particularly the changes on surgery protocols and…
- Conditions
- Gastric Cancer, Colorectal Cancer, Gastrointestinal Disease
- Trial name
- NCT04401124
- Testing
- no intervention
- Volunteers
- 500 people
- Sponsor
- Beijing Friendship Hospital
Colorectal Cancer
Real World Study of Regorafenib Versus Fruquintinib in Colorectal Cancer
This is an observational, ambispective cohort study. The aim is to compare the efficacy and safety of regorafenib versus fruquintinib conducted in China.
- Trial name
- NCT04431791
- Testing
- Regorafenib, Fruquintinib
- Where
- China
- Volunteers
- 268 people
- Sponsor
- Peking University
Metastatic Colorectal Cancer
A Trial of Capecitabine (Xeloda), Oxaliplatin and Irinotecan in Combination With Bevacizumab in 1st Line Treatment of Metastatic Colorectal Cancer
A Phase I-II Trial of Capecitabine (Xeloda), Oxaliplatin and Irinotecan in Combination with Bevacizumab in 1st Line Treatment of Metastatic Colorectal Cancer
- Trial name
- NCT01311050
- Testing
- Capecitabine (Xeloda), Oxaliplatin, Irinotecan, Bevacizumab
- Where
- Saudi Arabia
- Volunteers
- 46 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Choledochal Cyst
Host-Microbe Interactions in Biliary Dilatation
This study is an observational cohort study aimed at continuously enrolling patients with biliary dilatation and healthy controls.
- Trial name
- NCT07152496
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Esophageal Cancer, Gastric Cancer
Combination Chemotherapy Followed by Surgery and Intraperitoneal Chemotherapy in Treating Patients With Locally Advanced Stomach Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving chemotherapy drugs in different ways may kill more tumor cells.
- Trial name
- NCT00006038
- Testing
- cisplatin, docetaxel, floxuridine
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
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