Clinical trials: Digestive System Surgical Procedures
Choledochal Cyst
Efficacy and Safety of Surgical Treatment for Type IVa CBD
This study is a multicenter, bidirectional cohort study aimed at continuously enrolling patients with biliary dilatation from 25 medical centers in China.
- Trial name
- NCT07036848
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Liver Neoplasms, Liver/Hepatobiliary Cancer
CE-IOUS Impact on Surgical Strategy of Liver Tumours and Liver Metastases
Contrast-enhanced intraoperative ultrasound (CE-IOUS) plays an increasingly important role in the surgical therapy planning of primary liver lesions as well as liver metastases.
- Conditions
- Liver Neoplasms, Liver/Hepatobiliary Cancer, Colorectal Cancer Metastatic, Metastases
- Trial name
- NCT05261113
- Testing
- CE-IOUS
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- University of Regensburg
Appendicitis
Role of Wound Irrigation After Appendectomy
Surgical site infection is a common problem after open appendectomy. Irrigation of the surgical wound by topical antibiotics has been devised as a measure to reduce the incidence of wound infection.
- Trial name
- NCT03773224
- Testing
- Irrigation
- Where
- Egypt
- Volunteers
- 179 people
- Sponsor
- Mansoura University
Bowel Cleansing Prior to Clinical Procedures, Colorectal Anastomosis
Oral Antibiotics vs. No Antibiotics in Pediatric Colorectal Surgery
This study aims to evaluate whether giving oral antibiotics before elective colorectal surgery can improve recovery and reduce complications in children.
- Trial name
- PEACO (NCT07713433)
- Testing
- oral antibiotics, No Oral Antibiotics
- Where
- Pakistan
- Volunteers
- 74 people
- Sponsor
- Muhammad Zubair Shoukat
Biliary Tract Diseases
Cholecystitis in Villavicencio Hospitals
Background: Acute cholecystitis is a frequent cause of visits to the emergency ward. The complications of delays in attention and surgical therapy are substantial and should be considered to prevent them timely.
- Trial name
- NCT06048575
- Testing
- Cholecystectomy
- Where
- Colombia
- Volunteers
- 609 people
- Sponsor
- Hospital Departamental de Villavicencio
Postoperative Complications, Cardiovascular Diseases
Comparing Traditional Risk Scores and an AI-Based Multimodal Model for Predicting Cardiovascular Events After Gastrointestinal Surgery
The goal of this observational study is to develop and evaluate an artificial intelligence (AI)-based multimodal model for predicting major cardiovascular events within 30 days after gastrointestinal surgery in adults at Bach Mai…
- Conditions
- Postoperative Complications, Cardiovascular Diseases, Digestive System Surgical Procedures
- Trial name
- GI-MACE-AI (NCT07539532)
- Where
- Vietnam
- Volunteers
- 5,000 people
- Sponsor
- Bach Mai Hospital
Necrotizing Enterocolitis
Necrotizing Enterocolitis (NEC) Surgical Database
The general objectives of this protocol are to develop a multi-center prospective data collection process to identify risk factors for progression of Necrotizing Enterocolitis (NEC).
- Trial name
- NCT00120159
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Boston Children's Hospital
Appendicitis Acute, Peritonitis
Appendicitis in Adults and Children in France-A Prospective Study by the French Surgical Association Multicenter Cohort
Acute appendicitis still represents a surgical challenge, despite profound changes in practice in recent decades. The objective of this study was comprehensively document current surgical practices aimed at improving the…
- Trial name
- APPEA (NCT04214340)
- Testing
- evaluation of practices
- Volunteers
- 2,285 people
- Sponsor
- Association Francaise de Chirurgie
Acute Cholestatic Hepatitis
Emergent Laparoscopic Cholecystectomy With ICG Cholangiography
A consecutive case series report to share our experience in surgical outcome of patients who underwent emergency laparoscopic cholecystectomy guided by indocyanine green (ICG) fluorescence.
- Trial name
- ELG-ICGC (NCT06549881)
- Testing
- emergency laparoscopic cholecystectomy guided by indocyanine green (ICG) fluorescence
- Where
- China
- Volunteers
- 97 people
- Sponsor
- Peking Union Medical College Hospital
Digestive Cancer
ASSIST Tool and Surgical Randomized Controlled Trial Applicability
Background: The ASSIST tool is a graphical tool to represent and evaluate the applicability of a surgery trial to improve the translation of research to practice.
- Trial name
- ASTA (NCT01763489)
- Testing
- Applicability Assessment
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gastric Cancer, Laparoscopic Gastrectomy
Outcomes of Laparoscopic Gastrectomy
A prospective study of the results of laparoscopic approach of gastric carcinoma in western patients is designed. The working hypothesis proposes obtaining similar results to those obtained in the series reported by eastern…
- Trial name
- NCT04652986
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Juan Carlos Martín del Olmo
Colorectal Neoplasms, Colorectal Surgery
Attitudes and Technical Maneuvers Regarding Enterostomy Management and Stoma Creation Among Surgeons
This study was aiming to investigate Chinese surgeons' attitudes toward and technical preferences for stoma creation.
- Trial name
- NCT06735729
- Where
- China
- Volunteers
- 401 people
- Sponsor
- Peking University Cancer Hospital & Institute
Cancer of Colon, Surgery
Effect of Music Prehabilitation on Preoperative Anxiety Before Surgery
The goal of this multicenter randomized controlled trial is to investigate the effect of music prehabilitation on preoperative anxiety in patients undergoing elective oncological colorectal resection.
- Conditions
- Cancer of Colon, Surgery, Anxiety
- Trial name
- MU-PRIOR (NCT05982184)
- Testing
- Music
- Where
- 5 sites in Netherlands
- Volunteers
- 116 people
- Sponsor
- Erasmus Medical Center
Appendicitis, Acute, Appendectomy
Video-Based Grading of Intraoperative Adverse Events in Pediatric Laparoscopic Appendectomy
Acute appendicitis is the most common surgical emergency in children, and laparoscopic appendectomy is its standard treatment. Although intraoperative adverse events (iAEs) are recognized as an important determinant of surgical…
- Conditions
- Appendicitis, Acute, Appendectomy, Intraoperative Complications, Patient Safety
- Trial name
- PedAppy-iAE (NCT07794618)
- Testing
- Laparoscopic appendectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ahmet Burak Doğan, MD
Rectal Cancer, Organ Preservation
Treatment Strategy for Rectal Cancer Patients With Complete Clinical Response
This was a propensity-score matched observational analysis, comparing the oncological outcome of surgical resection vs watch and wait apporach for rectal cancer patients with a cCR.
- Trial name
- NCT03846726
- Testing
- standard TME surgery
- Where
- China
- Volunteers
- 513 people
- Sponsor
- Yuan-hong Gao
Crohn's Disease, Inflammatory Bowel Disease
A Randomized Controlled Trial of VSL#3 for the Prevention of Endoscopic Recurrence Following Surgery for Crohn's Disease.
This randomized placebo-controlled double-blind, multi-centre trial will determine the efficacy of the probiotic VSL#3 in the prevention of Crohn's disease development following surgical resection and re-anastomosis.
- Trial name
- NCT00175292
- Testing
- Probiotic - VSL#3
- Where
- 17 sites in Canada
- Volunteers
- 120 people
- Sponsor
- University of Alberta
Appendicitis
Antimicrobial Stewardship in Pediatric Surgery
Acute appendicitis is a common surgical emergency in children. Non-perforated appendicitis patients do not require antibiotics after appendectomy.
- Trial name
- AbxPS (NCT02270996)
- Testing
- Antimicrobial Stewardship Program
- Volunteers
- healthy volunteers welcome
- Sponsor
- Alberta Children's Hospital
Pathology
Incidental Cancer in Gallbladder Surgical Specimens Focus on Elderly Patients
Causes such as long-term stones and polyp are thought to play a role in the etiology of gallbladder cancer. The routine histopathological examination provides the detection of incidental gallbladder cancers.
- Trial name
- NCT04352478
- Testing
- Histopathological result
- Where
- Turkey (Türkiye)
- Volunteers
- 2,389 people
- Sponsor
- Dr. Ersin Arslan Education and Training Hospital
Colon Rectal Cancer, Surgical Site Infection
Surveillance and Implementation of a Bundle of Care to Reduce Surgical Site Infection in Colorectal Surgery (CCR-VINCat)
The Nosocomial Infection Surveillance Program in Catalonia (VINCat) monitors surgical site infection (SSI) in elective colorectal surgery since 2007 in 55 public and private acute care hospitals.
- Trial name
- CCR-VINCat (NCT04496635)
- Testing
- Implementation of a bundle of care
- Where
- Spain
- Volunteers
- 60,000 people
- Sponsor
- Hospital de Granollers
Necrotizing Enterocolitis
Qualitative Study of Surgeons With Prospective Patient Follow-up
Necrotising enterocolitis (NEC) is a devastating disease which causes severe bowel inflammation resulting in babies becoming critically unwell.
- Trial name
- NECqual (NCT06032676)
- Where
- United Kingdom
- Volunteers
- 75 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust