Clinical trials: Digestive System Surgical Procedures
Surgical Procedures, Operative
Determining Universal Processes Related to Best Outcome in Emergency Gastrointestinal Surgery: an International Evaluation
A multicentre, international evaluation of emergency abdominal surgery to establish surgical outcomes and identify common, modifiable best practice processes.
- Trial name
- GlobalSurg-1 (NCT02179112)
- Testing
- Emergency Abdominal Surgery
- Where
- United Kingdom
- Volunteers
- 10,745 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Pancreas Disease, Liver Diseases
Results of Surgical Treatment of the Hepatobiliopancreatic Surgical Unit
The main aims of this study are: 1. - to evaluate post-surgical morbidity and mortality outcomes, following the criteria and the definitions from Claven-Dindo and ISGPS international classifications, of the patients operated by…
- Conditions
- Pancreas Disease, Liver Diseases, Surgical Procedure, Unspecified, Bile Duct Diseases
- Trial name
- HPB (NCT04556019)
- Testing
- Hepatobiliopancreatic surgery
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- Fundacion Miguel Servet
Rectal Cancer, Pelvic Cancer
Advanced Pelvic Surgical Oncology Database - Prospective Observational Study
Retrospective and prospective observational study of patients undergoing advanced pelvic oncological resection for maligancy including multi visceral resection, beyond TME resection and sacrectomy/flap reconstruction/urinary…
- Conditions
- Rectal Cancer, Pelvic Cancer, Gynecologic Cancer, Colon Cancer
- Trial name
- NCT05696002
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Glasgow Royal Infirmary
Surgical Site Infection, Colorectal Cancer
Prophylatic Effect Preoperative Antibiotics With Mechanical Bowel Preparation in SSIs: A Propensity Analysis
Surgical site infections (SSIs) are a major postoperative complication after colorectal surgery. Current study aims to evaluate prophylactic function of oral antibiotic intake (OA) in combination with mechanical bowel preparation…
- Trial name
- NCT04258098
- Testing
- Oral antibiotics ( Streptomycin ,metronidazole )
- Volunteers
- 806 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Rectal Prolapse
A Modified Technique to Facilitate Pealing of the Rectal Mucosa in Delorme Operation
The aim of this study is to evaluate the investigator new modification for delorme procedure in patients with rectal prolapse , assessing intra-operative morbidity and recurrence rate .
- Trial name
- NCT02901210
- Testing
- Modified delorme procedure
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Yasser Mohamed Abdel-samii
Biliary Tract Diseases
Cholecystitis in Villavicencio Hospitals
Background: Acute cholecystitis is a frequent cause of visits to the emergency ward. The complications of delays in attention and surgical therapy are substantial and should be considered to prevent them timely.
- Trial name
- NCT06048575
- Testing
- Cholecystectomy
- Where
- Colombia
- Volunteers
- 609 people
- Sponsor
- Hospital Departamental de Villavicencio
Anorectal Malformations
Outcomes in ARMs: Comparison Between Surgical Techniques in Patients With Perineal or Vestibular Fistula - a Multicenter Italian Study
This is a national, multicenter, retro-prospective longitudinal cohort study evaluating mid- and long-term outcomes of different surgical techniques used for the correction of anorectal malformations (ARM) with perineal or…
- Trial name
- MAR-ITA (NCT07438691)
- Where
- 21 sites in Italy
- Volunteers
- 500 people
- Sponsor
- Meyer Children's Hospital IRCCS
Hypertrophic Pyloric Stenosis, Spinal Anesthesia
Spinal Anesthesia and General Anesthesia for Pyloromyotomy - Surgical Outcomes a Comparison Retrospective Study
Background: The purpose of this retrospective study is to evaluate surgical outcomes of pyloromyotomy in infants performed under spinal anesthesia compares to general anesthesia.
- Conditions
- Hypertrophic Pyloric Stenosis, Spinal Anesthesia, General Anesthesia
- Trial name
- NCT03095144
- Testing
- Spinal anesthesia, General anesthesia
- Volunteers
- 100 people
- Sponsor
- Bnai Zion Medical Center
Colon Cancer, Diverticulitis
General Surgical Outcomes Quality Improvement Database (UH-SOCRATES)
A database has been established to track the outcomes of all cases performed in the University Hospitals Department of Surgery in an effort to improve quality of surgical performance and case management.
- Conditions
- Colon Cancer, Diverticulitis, Colorectal Polyps, Crohn's Disease
- Trial name
- SOCRATES (NCT00622557)
- Where
- United States
- Volunteers
- 200,000 people
- Sponsor
- University Hospitals Cleveland Medical Center
Hirschsprung Disease
Laparoscopic Assisted Pull-through Versus Other Surgical Procedures for Treatment of Hirschsprung Disease
To evaluate the outcomes of laparoscopic pull-through concerning constipation, incontinence and enterocolitis in comparison of other surgical procedures for treatment of Hirschsprung disease.
- Trial name
- NCT03269812
- Testing
- laparoscopic assisted pull-through oeration
- Volunteers
- 60 people
- Sponsor
- Assiut University
Colonic Neoplasms, Colorectal Neoplasms
Study of an Individualized Vaccine Targeting Neoantigens in Combination With Immune Checkpoint Blockade for Patients With Colon Cancer
The primary objective is to assess and characterize the antitumor activity and safety and tolerability of adjuvant treatment with an individualized neoantigen vaccine called GRT-C901/GRT-R902 (chimpanzee adenovirus [ChAd] and…
- Trial name
- NCT05456165
- Testing
- GRT-C901, GRT-R902, Atezolizumab
- Where
- 3 sites in United States
- Sponsor
- Gritstone bio, Inc.
Necrotising Enterocolitis Neonatal
Neonatal Laparotomy - A Trial Investigating the Impact of Location of Surgery
This is a pilot randomised trial allocating neonates requiring emergency laparotomy to surgery either on the neonatal unit or in the operating theatre.
- Trial name
- NeoLap (NCT07754435)
- Testing
- IN theatre, ON unit
- Volunteers
- 15 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Incisional Hernia, Incision Infection
Total 102 Natural Orifice Specimen Extractions Following Laparoscopic Colorectal Resections
In the development of surgical technique, laparoscopic surgery has created a major breaking point. Although laparoscopy (decreased hospital stay, decreased incisional hernia and wound infection rate…) provides a remarkable…
- Trial name
- NCT04394988
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Inonu University
Pancreatic Neoplasms, Anesthesia
Evaluation of Prehabilitation as a Strategy to Minimize Surgical Risk in Pancreatic Surgery: Efficacy and Determining Factors.
Several studies in major abdominal surgery demonstrated that preoperative optimization of surgical patients through prehabilitation is associated with fewer postoperative complications.
- Trial name
- NCT05489419
- Testing
- Multimodal Prehabilitation
- Where
- Spain
- Volunteers
- 56 people
- Sponsor
- Hospital Clinic of Barcelona
Complications of Treatment, Complication of Surgical Procedure
A Trial on Treatments of Hirschsprung Allied Disease
The present study was designed to compare the efficacy of conservative treatment to operative treatment for improvement of constipation symptoms in children with Hirschsprung allied disease
- Conditions
- Complications of Treatment, Complication of Surgical Procedure, Megacolon, Not Hirschsprung
- Trial name
- NCT02212054
- Testing
- conservative, operative
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Tongji Hospital
Colostomy Stoma, Colostomy Complication
Impact of Surgical Technique on Post-operative Complications in Urgency Ostomy Confection
This is a single-center retrospective cohort study on cancer patients who underwent emergency ostomy. Our objective was to compare the incidence of surgical complications as well as the length of hospital stay among three…
- Conditions
- Colostomy Stoma, Colostomy Complication, Obstruction Bowel, Surgical Complication
- Trial name
- NCT05635188
- Testing
- Intestinal ostomy confection
- Where
- Brazil
- Volunteers
- 154 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Appendicitis
Antimicrobial Stewardship in Pediatric Surgery
Acute appendicitis is a common surgical emergency in children. Non-perforated appendicitis patients do not require antibiotics after appendectomy.
- Trial name
- AbxPS (NCT02270996)
- Testing
- Antimicrobial Stewardship Program
- Volunteers
- healthy volunteers welcome
- Sponsor
- Alberta Children's Hospital
Hepatocellular Carcinoma, Portal Vein Thrombosis
Surgical Outcome of HCC With Portal Vein Tumor Thrombosis on the Basis of Risk Scoring
The goal of this multicenter retrospective cohort study is to investigate the clinical outcomes and prognostic factors after hepatic resection in patients with HCC exhibiting PVTT, and to develop a prognostic index that can be…
- Conditions
- Hepatocellular Carcinoma, Portal Vein Thrombosis, Prognosis
- Trial name
- NCT06005883
- Where
- South Korea
- Volunteers
- 332 people
- Sponsor
- Keimyung University Dongsan Medical Center
Gastric Cancer
Learning Curve and Optimization of Robotic Gastrectomy
we explore the learning curve and the impact of technique optimization on surgical outcomes and the first to construct a referenceable learning phase for performing robotic gastric cancer surgery.
- Trial name
- NCT05715775
- Where
- China
- Volunteers
- 527 people
- Sponsor
- Fujian Medical University
Liver Fibrosis
Development of Novel MRI Methods for Detecting, Discriminating, and Measuring Liver Fibrosis and Congestion in Fontan Patients
In this research study, the investigators will conduct a prospective cross-sectional study of pediatric and adult Fontan patients that will correlate a variety of quantitative MRI biomarkers with histopathologic data.
- Trial name
- NCT03539757
- Testing
- Non-Contrast Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati