Clinical trials: Drug-eluting Stent
Coronary Artery Disease
Evaluation of Effectiveness and Safety of XIENCE PRIME Stent (IRIS-PRIME)
The objective of this study is to evaluate effectiveness and safety of XIENCE PRIME stent in the "real world" daily practice as compared with other drug eluting stents (DESs)
- Trial name
- NCT01348399
- Where
- 29 sites in South Korea
- Volunteers
- 2,000 people
- Sponsor
- Seung-Jung Park
Chronic Coronary Occlusion, Vascular Disease
XIENCE V® Everolimus Eluting Coronary Stent System USA Post-Approval Study (XIENCE V® USA Long Term Follow-up Cohort)
XIENCE V USA is a prospective, multi-center, multi-cohort post-approval study. The objectives of this study are To evaluate XIENCE V EECSS continued safety and effectiveness during commercial use in real world settings, and To…
- Conditions
- Chronic Coronary Occlusion, Vascular Disease, Myocardial Ischemia, Coronary Artery Stenosis
- Trial name
- XVU-LTF (NCT01120379)
- Testing
- XIENCE V® EECSS
- Where
- United States
- Volunteers
- 5,034 people
- Sponsor
- Abbott Medical Devices
Erythrocyte Transfusion, Percutaneous Coronary Intervention
Bare Metal Stents and Drug Eluting Stents in Patients Who Underwent Blood Transfusion
Retrospective cohort study of Korean National Healthcare Insurance Database. To investigate clinical outcomes of bare metal stents versus drug eluting stents in patients who underwent periprocedural red blood cell transfusion.
- Conditions
- Erythrocyte Transfusion, Percutaneous Coronary Intervention, Revascularization
- Trial name
- TFPCI2 (NCT03788148)
- Testing
- Stent, red blood cell transfusion
- Where
- South Korea
- Volunteers
- 28,322 people
- Sponsor
- Samsung Medical Center
Myocardial Infarction
Myocardial Regeneration and Angiogenesis in Myocardial Infarction With G-CSF and Intra-Coronary Stem Cell Infusion-3-DES
This trial was performed to evaluate the safety of G-CSF based stem cell therapy and to compare outcome of intracoronary infusion of mobilized PBSCs between patients with AMI and OMI.
- Trial name
- NCT00291629
- Testing
- G-CSF (Dong-A pharmaceutical, Seoul, Korea), collection of mobilized peripheral blood stem cells, Intracoronary infusion of mobilized cells
- Where
- South Korea
- Volunteers
- 96 people
- Sponsor
- Seoul National University Hospital
Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD))
MIRAGE Study: Clinical Outcomes of the Mamba Sirolimus-Eluting PTCA Balloon
This Clinical Evaluation Report (CER) covers the Mamba Sirolimus-Eluting PTCA Balloon catheter intended for the treatment of coronary artery disease in de novo or in-stent restenosis lesions.
- Trial name
- NCT07326735
- Testing
- Mamba Sirolimus-Eluting PTCA Balloon, Percutaneous Coronary Angioplasty with Sirolimus-Coated Balloon
- Where
- 2 sites in Burma, Malaysia
- Volunteers
- 360 people
- Sponsor
- Frisch Medical Device Private Limited
Coronary Artery Disease, Chronic Total Occlusion of Coronary Artery
Evaluation of Long Coronary Artery Stents With Third-generation Dual-source Computed Tomography Angiography
The goal of this clinical trial is to assess third-generation dual-source coronary computed tomography angiography (CCTA) performance in the evaluation of long coronary stents in patients with coronary artery chronic total…
- Trial name
- NCT06543641
- Testing
- Coronary computed tomography angiography, Invasive coronary angiography
- Where
- Finland
- Volunteers
- 45 people
- Sponsor
- Lauri Mansikkaniemi
Vascular Diseases, Stent Complication
Eluvia DES for the Patients with Femoropopliteal Artery Lesions.
This study is a multicenter, prospective, observational study, aiming to enroll 400 patients with peripheral arterial disease in the femoral-popliteal segment implanted with Eluvia stent. Each patient was followed up for 2 years.
- Trial name
- NCT05522218
- Testing
- Eluvia drug eluting stent
- Where
- China
- Volunteers
- 400 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Saphenous Vein Graft Disease
A Meta-analysis of Drug Eluting Stents Versus Bare Metal Stents in Saphenous Vein Graft Disease
A meta-analysis to compare outcomes of drug eluting stents (DES) versus bare metal stent (BMS) in saphenous vein graft (SVG) disease.
- Trial name
- NCT01036048
- Testing
- drug eluting stent, bare metal stent
- Volunteers
- 5,806 people
- Sponsor
- Catholic University of the Sacred Heart
Acute Coronary Syndrome, High Bleeding Risk
LEADERS FREE II: BioFreedom™ Pivotal Study
This study aims to confirm non-inferiority of the BioFreedom™ Drug Coated Stent to the Gazelle™ Bare Metal Stent arm of the Leaders Free study (NCT01623180) in high bleeding risk patients.
- Trial name
- NCT02843633
- Testing
- BioFreedom™ Drug Coated Coronary Stent System, Antiplatelet Drug
- Where
- 66 sites in United States, Canada and 5 more
- Volunteers
- 1,203 people
- Sponsor
- Biosensors Europe SA
Coronary Artery Disease, Percutaneous Coronary Intervention (PCI)
Drug Coated Balloon vs. Drug-eluting Stent in Patients With Coronary Artery Disease
Studies exploring the feasibility of drug-eluting balloon (DCB) in de-novo coronary lesions are limited. There are scarce data comparing DCB with drug-eluting stent (DES) in patients with high bleeding risk (HBR), a situation in…
- Trial name
- DCB_DES (NCT07442500)
- Testing
- Drug coated balloon, Drug-eluting stent
- Where
- South Korea
- Volunteers
- 470,000 people
- Sponsor
- Samsung Medical Center
Coronary Artery Disease, Stable Angina
BMX Alpha Registry: a Post-market Registry of the BioMatrix Alpha TM
Prospective, multi-center, registry designed to enrol up to 2,000 patients in up to 35 International centers. All patients will receive a BioMatrix AlphaTM stent as per clinical practice and will be followed for 2 years for data…
- Conditions
- Coronary Artery Disease, Stable Angina, Ischemia, Acute Coronary Syndrome
- Trial name
- NCT02871622
- Testing
- BioMatrix AlphaTM
- Where
- United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- Biosensors Europe SA
Coronary Artery Disease
Evaluation of Effectiveness and Safety of the GENOUS STENT (IRIS-GENOUS STEMI)
The objective of this study is to evaluate effectiveness and safety of GENOUS EPC-coated stent in patients with STEMI with other drug-eluting stents (DESs).
- Trial name
- NCT01348373
- Where
- 16 sites in South Korea
- Volunteers
- 464 people
- Sponsor
- Seung-Jung Park
Coronary Arteriosclerosis, Angina Unstable
Stents, Drug Eluting Stents, and CABG- Financial and Clinical Impact.
Options for coronary revascularization include stent implantation and coronary bypass surgery. Both modalities have their unique advantages and disadvantages in terms of clinical outcomes as well as financial impact on the…
- Conditions
- Coronary Arteriosclerosis, Angina Unstable, Myocardial Infarction
- Trial name
- NCT00394680
- Volunteers
- 700 people
- Sponsor
- Shaare Zedek Medical Center
In-stent Coronary Artery Restenosis
In-stent Restenosis in Patients With Patent Previous Bare Metal Stent
Intra-coronary stents deployment reduces the rate of angiographic restenosis as compared to Balloon angioplasty. in-stent restenosis, usually defined as ≥50 percent diameter stenosis within previously deployed stent, is most…
- Trial name
- NCT01296399
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Rambam Health Care Campus
Coronary Thrombosis, Tomography, Optical Coherence
Independent OCT Registry on Very Late Bioresorbable Scaffold Thrombosis
Bioresorbable vascular scaffold (BVS, ABSORB BVS1.1, Abbott Vascular) has been approved (CE mark) and is used in daily clinical practice.
- Conditions
- Coronary Thrombosis, Tomography, Optical Coherence, Drug-Eluting Stents
- Trial name
- INVEST (NCT03180931)
- Testing
- Bioresorbable vascular scaffold
- Where
- 19 sites in Austria, Belgium and 8 more
- Volunteers
- 36 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Coronary Artery Disease
Study of the Paclitaxel-Coated Balloon Catheter in Bifurcated Coronary Lesions
This study in bifurcated coronary lesions compares the new technology of the paclitaxel-eluting balloon with the usual technique until now of "provisional stenting" with the paclitaxel-eluting stent in the main branch.
- Trial name
- BABILON (NCT01278186)
- Testing
- Balloon angioplasty, Stent implantation
- Where
- 9 sites in Spain
- Volunteers
- 190 people
- Sponsor
- B.Braun Surgical SA
Vessel Restenosis
Dexamethasone-Eluting Stent in Acute Coronary Syndrome to Prevent Restenosis
The major obstacle of the long- termed success of percutaneous coronary intervention (PCI) is the restenosis. Restenosis results from complex pathophysiological response of the vascular tissue to the balloon injury.
- Trial name
- NCT00190099
- Testing
- Dexamethasone-Eluting Stent
- Volunteers
- 40 people
- Sponsor
- Far Eastern Memorial Hospital
Coronary Artery Disease
Drug-coated Balloon Treatment
Evaluation of the efficacy and clinical outcomes of drug-eluting balloon therapy in ticyaici coronary artery disease.
- Trial name
- DCB-ONE TR (NCT07794839)
- Testing
- drug coated balloon, drug eluting stent
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Istanbul Mehmet Akif Ersoy Educational and Training Hospital
Cardiovascular Diseases, Vascular Disease
An Observational Registry Using Drug Eluting Stents (DES) in Patients in a Real-World Setting (DEScover Registry).
The DEScover Registry is designed to observe the results of using Drug Eluting Stents (DES) in patients in a real-world setting.
- Conditions
- Cardiovascular Diseases, Vascular Disease, Arterial Occlusive Disease, Arteriosclerosis
- Trial name
- DESCOVER (NCT00489320)
- Testing
- Cypher Stent
- Where
- United States
- Volunteers
- 7,759 people
- Sponsor
- Cordis US Corp.
Coronary Artery Disease
Evaluation of Effectiveness and Safety of BIOMATRIX Stent (IRIS-BIOMATRIX)
The objective of this study is to evaluate effectiveness and safety of BioMatrix stent in the "real world" daily practice as compared with first-generation drug-eluting stents (sirolimus- or paclitaxel-eluting stents).
- Trial name
- NCT01350778
- Where
- 20 sites in South Korea
- Volunteers
- 837 people
- Sponsor
- Seung-Jung Park