Clinical trials: Ductus
Patent Ductus Arteriosus
Early Treatment Versus Expectant Management of PDA in Preterm Infants
Patent ductus arteriosus (PDA) in very preterm newborns is associated with severe neonatal mor-bidity: intraventricular hemorrhage (IVH), bronchopulmonary dysplasia (BPD), necrotizing en-terocolitis (NEC), retinopathy of…
- Trial name
- NCT03860428
- Testing
- Ibuprofen, Paracetamol, Expectant Management
- Where
- Ukraine
- Volunteers
- 208 people
- Sponsor
- Lviv National Medical University
Patent Ductus Arteriosus
Early Treatment Versus Expectative Management of PDA in Preterm Infants
Much controversy exists about the optimal management of a patent ductus arteriosus (PDA) in preterm infants, especially in those born at a gestational age <28 weeks and/or a birth weight ≦1000 grams due to a lack of evidence for…
- Trial name
- BeNeDuctus (NCT02884219)
- Testing
- Ibuprofen, Expectative Management, Indomethacin
- Where
- 13 sites in Belgium, Netherlands
- Volunteers
- 273 people
- Sponsor
- Radboud University Medical Center
Patent Ductus Arterioses
The Impact of Platelet Functions on Spontaneous Ductal Closure in Preterm Infants
Although thrombocytopenia has been reported as a risk factor for patent ductus arterioses, there is lack of data on the function of platelets in ductal closure.
- Trial name
- PFA100 (NCT02010879)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ankara University
Patent Ductus Arteriosus After Premature Birth, Hyper Bilirubinemia
The Effects of Phototherapy in Preterm Infants Pda
The study was designed to assess whether chest shielding during phototherapy reduces the incidence of PDA, as assessed by serial echocardiographic examinations, in a population of extremely preterm infants born at lower 30 week…
- Trial name
- NCT03675425
- Testing
- Group 1: non chest shielding, Group 2: chest shielding
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Patent Ductus Arteriosus
Timing of PDA Closure and Respiratory Outcome in Premature Infants
The investigators propose the present study with the following aims: to determine whether early patent ductus arteriosus (PDA) treatment with ibuprofen treatment at the onset of clinical symptoms is superior to late ibuprofen…
- Trial name
- NCT00802685
- Testing
- Early ibuprofen
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- University of Miami
Patent Ductus Arteriosus, Surgery
Early Treatment Versus Delayed Conservative Treatment of the Patent Ductus Arteriosus
The primary goal of the trial is to compare two different Patent Ductus Arteriosus (PDA) treatment approaches: 1) an "early treatment" approach or 2) a "conservative" approach.
- Conditions
- Patent Ductus Arteriosus, Surgery, Necrotizing Enterocolitis, Intestinal Perforation
- Trial name
- PDA:TOLERATE (NCT01958320)
- Testing
- pharmacologic treatment of the PDA, no pharmacologic treatment of the PDA, NSAID
- Where
- 18 sites in United States, Sweden and 2 more
- Volunteers
- 202 people
- Sponsor
- University of California, San Francisco