Clinical trials: Dyspnea; Asthmatic
Shortness of Breath, Chest Pain
Checklists Resuscitation Emergency Department
The study will systematically evaluate how an emergency manual-a collection of checklists and fact sheets-affects the performance of resuscitation teams during the management of priority one patients in an emergency department.
- Conditions
- Shortness of Breath, Chest Pain, Abdominal Pain, Altered Mental Status
- Trial name
- NCT05649891
- Testing
- Emergency Manual
- Volunteers
- 2,000 people
- Sponsor
- Region Skane
Asthma, Bronchospasm
Virtual Teach-to-Goal Education vs. Brief Education for Children
The purpose of this study is to evaluate the effectiveness of two different ways to teach hospitalized children how to use a metered dose inhaler and to follow-up after discharge home from the hospital to determine durability of…
- Conditions
- Asthma, Bronchospasm, Shortness of Breath
- Trial name
- V-TTG vs BI (NCT04373499)
- Testing
- Virtual Teach to Goal, Brief Intervention
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Chicago
COPD, Asthma
Participatory Action Research to Evaluate the Delivery of the MISSION ABC Service Model and Assess Health Service and Clinical Outcomes
Innovations aimed at improving new patient identification, diagnosis, nonpharmacological treatment, supported self-management, and remote monitoring, together with new methods of clinical support could improve outcomes in…
- Conditions
- COPD, Asthma, Breathlessness
- Trial name
- NCT03096509
- Testing
- MISSION ABC Integrated Care clinic
- Where
- United Kingdom
- Volunteers
- 342 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Asthma
Effects of Papworth Breathing With or Without Bridge Pose Yoga in Asthma Patients
Asthma is a chronic condition causing airway inflammationandconstriction, leading to symptoms like shortness of breath, wheezing, andchest tightness.
- Trial name
- NCT07440953
- Testing
- Papeworth Breathing, Pap-worth Breathing + Bridge Pose Yoga
- Where
- Pakistan
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Asthma, Asthma (Diagnosis)
Intercostal and Thoracic Cage Stretching on Chest Expansion , Dyspnea ,Oxygen Saturation in Asthma
The rationale of this study is to clarify distinct role of these two stretching techniques in pulmonary rehabilitation. Insight gained from this research could provide evidence based recommendations for implementing these…
- Trial name
- NCT07331662
- Testing
- thoracic cage stretching, intercostal stretching
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Riphah International University
Asthma
Efficacy and Safety Study of QAW039 in Patients With Severe Asthma Inadequately Controlled With Standard of Care Asthma Treatment.
This study aimed to determine the efficacy and safety of QAW039 150 mg and QAW039 450 mg, compared with placebo, when added to GINA (Global Initiative for Asthma) steps 4 and 5 standard-of- care (SoC) asthma therapy (GINA 2016)…
- Trial name
- NCT02555683
- Testing
- QAW039
- Where
- 234 sites in United States, Argentina and 25 more
- Volunteers
- 894 people
- Sponsor
- Novartis Pharmaceuticals
Asthma
Epinephrine Inhalation Aerosol USP: For Evaluation Of Efficacy And Safety In Asthma Patients
This clinical study evaluates the 12-week efficacy and safety of Epinephrine HFA Inhalation Aerosol HFA the proposed HFA formulation of metered dose inhaler (MDI) of Epinephrine, in comparison to a Placebo-HFA control MDI and the…
- Trial name
- NCT01357642
- Testing
- Epinephrine inhalation aerosol
- Where
- 33 sites in United States
- Volunteers
- 373 people
- Sponsor
- Amphastar Pharmaceuticals, Inc.
Asthma (Diagnosis)
Predictive Factors for a Positive Exercise Bronchial Hyperresponsiveness Test
Exertional dyspnea has a significant impact on a child's daily life. Current guidelines recommend performing an exercise challenge test to confirm or rule out exercise-induced bronchoconstriction (EIB).
- Trial name
- PredEIB (NCT07766460)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Central Hospital, Nancy, France
Asthma in Children, Dyspnea; Asthmatic
Mechanisms for Dyspnea on Exertion in Children With Obesity and Asthma: Distinct Physiological Phenotypes
The overall objective of this study is to better understand the respiratory mechanisms provoking dyspnea on exertion in obese asthmatic children.
- Conditions
- Asthma in Children, Dyspnea; Asthmatic, Obesity, Childhood
- Trial name
- NCT04184609
- Testing
- Control, Albuterol
- Where
- United States
- Sponsor
- Ohio State University
Asthma
Study of Safety of QAW039 in Patients With Asthma Inadequately Controlled on Standard-of-care Asthma Treatment
This study was a 2-treatment period, randomized, multicenter parallel-group study. The overall purpose of this study was to provide long- term safety data for fevipiprant (QAW039) (Dose 1 and Dose 2), compared with placebo, when…
- Trial name
- NCT03052517
- Testing
- QAW039 150 mg, QAW039 450 mg
- Where
- 347 sites in United States, Argentina and 40 more
- Volunteers
- 2,538 people
- Sponsor
- Novartis Pharmaceuticals
Exercise Induced Laryngeal Obstruction, Asthma in Children
Prevalence of EILO Among Children With Asthma
The goal of this cross-sectional study is to investigate the prevalence of Exercise Induced Laryngeal Obstruction (EILO) in children with asthma.
- Conditions
- Exercise Induced Laryngeal Obstruction, Asthma in Children, Exercise-Induced Bronchospasm, Exercise-Induced Bronchoconstriction
- Trial name
- NCT06480084
- Testing
- Continuous Laryngoscopy during Exercise Test (CLE test)
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Medisch Spectrum Twente
Asthma
A Study of Omalizumab (Xolair) in Subjects With Moderate to Severe Persistent Asthma (EXTRA)
This is a multicenter, randomized, double-blind, placebo-controlled study of the efficacy, safety, and tolerability of subcutaneously administered Xolair as add-on therapy for the treatment of subjects aged 12-75 years old…
- Trial name
- NCT00314574
- Testing
- omalizumab (Xolair), corticosteroids, long-acting beta-agonists
- Volunteers
- 850 people
- Sponsor
- Genentech, Inc.
Asthma, Pneumonia
PECO Air Purification in Hospital Rooms to Improve Health Outcomes for Pediatric Respiratory Distress
This study will investigate the efficacy of a novel air purification technology, Photo Electrochemical Oxidation (PECO), has on pediatric patients hospitalized for respiratory distress.
- Conditions
- Asthma, Pneumonia, Respiratory Distress Syndrome
- Trial name
- NCT03647397
- Testing
- Photo Electrochemical Oxidation (PECO) for Air Purification
- Where
- United States
- Volunteers
- 274 people
- Sponsor
- Molekule
Shortness of Breath, Asthma in Children
The Effect of Nebulized Epinephrine in Asthma Exacerbation in Pediatric Age Group With the Standard Treatment Compared to Standard Treatment Using Improvement PRAM Score as a Primary Outcome
Our study aiming to look in improvement of Pediatric Respiratory Assessment Measure (PRAM) score as a primary outcome. The secondary outcomes involving the need for second step management, need for admission and possible side…
- Conditions
- Shortness of Breath, Asthma in Children, Epinephrine Causing Adverse Effects in Therapeutic Use, Salbutamol Adverse Reaction
- Trial name
- NCT05667727
- Testing
- nebulized epinephrine, Salbutamol
- Where
- Oman
- Volunteers
- 30 people
- Sponsor
- Oman Medical Speciality Board
Asthma
Effects of Abdominal Binder on Dysnea, Control Pause and Quality of Life in Asthmatic Patients
This study investigates the effects of using an abdominal binder as an adjunct to diaphragmatic breathing in asthma patients. The goal is to determine if the binder improves respiratory mechanics, specifically reducing dyspnea…
- Trial name
- NCT07612384
- Testing
- Abdominal binder -assisted diaphragmatic breathing, Conventional diaphragmatic breathing exercise
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Foundation University Islamabad
Asthma Control Level
Effects of Video Animation-Assisted Inhaler Medication Education on Medication Adherence, Attack Frequency, and Dyspnea for Asthma Patients
Asthma is a chronic airway inflammation characterized by recurrent attacks, airway hyperresponsiveness, mucus hypersecretion, and airway obstruction.
- Trial name
- NCT07134647
- Testing
- video animation-supported inhaler medication training
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Asthma, Dyspnea; Asthmatic
Asthma Diagnosis Verified by Lung Function
Guidelines suggests that asthma should not be treated prior to a reversibility test and/or an assessment with peak expiratory flow (PEF) unless there is a clinical urgency for the patient to be treated.
- Conditions
- Asthma, Dyspnea; Asthmatic, Diagnoses Disease
- Trial name
- ADVERT (NCT04652141)
- Testing
- AsthmaTuner
- Where
- Sweden
- Volunteers
- 146 people
- Sponsor
- Björn Nordlund
Asthma, Heart Failure
The General Breathing Record Study
This study will test the use of a new handheld device (called the N-Tidal C), that measures a person's tidal breath carbon dioxide, in diagnosing the cause of someone's breathlessness.
- Conditions
- Asthma, Heart Failure, Pneumonia, Motor Neuron Disease
- Trial name
- GBRS (NCT03356288)
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- TidalSense
Asthma, Asthma in Children
Prospective Multicentre Study on Symptoms in First-onset Bronchial Asthma in Children and Adolescents
Bronchial asthma may present with symptoms other than the commonly reported complaints (cough, chest tightness, shortness of breath and wheezing).
- Conditions
- Asthma, Asthma in Children, Dyspnea, Cough
- Trial name
- NCT06201494
- Where
- Czechia
- Volunteers
- 80 people
- Sponsor
- Charles University, Czech Republic
Respiratory Distress Syndrome, Pneumonia
Telemedicine in the Generals Practitioners Office
Pediatrician does physical examination through telemedicine and in real life to see whether the telemedicine consultation corresponds with the real life examination. Goal is to determine: 1. Check practical feasability 2.
- Conditions
- Respiratory Distress Syndrome, Pneumonia, Bronchiolitis, Croup
- Trial name
- NCT04168554
- Testing
- Telemedicine
- Volunteers
- 40 people
- Sponsor
- Rijnstate Hospital