Clinical trials: Dyssomnias
Insomnia, Traumatic Brain Injury
Non-Pharmacological Treatments for Insomnia in Chronic Traumatic Brain Injury
The purpose of this clinical trial is to assess the relative efficacy of two non-pharmacological interventions for insomnia in Veterans suffering from chronic mild traumatic brain injury (mTBI).
- Trial name
- NCT03261674
- Testing
- CBT-I, ABT-I
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- VA Office of Research and Development
Smith-Magenis Syndrome (SMS)
Natural History Study of Smith-Magenis Syndrome
This study will examine how a rare disease called Smith-Magenis syndrome (SMS) affects people and how they change over time. SMS is caused by a small chromosome 17p11.2 deletion (missing piece).
- Trial name
- NCT00013559
- Where
- United States
- Volunteers
- 593 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Autism Spectrum Disorder, Insomnia
SweetDreams Sleep Study for Children With Autism
This proposal will acquire preliminary data on the feasibility and effectiveness of an innovative and scalable strategy for improving access to effective sleep health care for preschool-aged children with Autism Spectrum Disorder…
- Trial name
- NCT04452045
- Testing
- SweetDreams
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Rett Syndrome, Prader-Willi Syndrome
Sleep Abnormalities in Rare Genetic Disorders: AS, RTT, and PW
This study will investigate sleep behavior in subjects with Angelman Syndrome, Rett Syndrome or Prader-Willi Syndrome. The study will also investigate sleep behavior in healthy siblings of subjects with Angelman Syndrome, Rett…
- Conditions
- Rett Syndrome, Prader-Willi Syndrome, Angelman Syndrome, Sleep Problems
- Trial name
- RDCRN (NCT02670694)
- Where
- 9 sites in United States
- Volunteers
- 804 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Sleep, Sleep Disturbance
Impact of Bedtime Routines on Sleep and Development in Toddlers
Investigators will recruit up to 100 families (children aged 12.0 to 14.9 months and their primary caregivers) at their scheduled 12-month well child care infant visit at Temple Pediatric Care.
- Conditions
- Sleep, Sleep Disturbance, Child Development
- Trial name
- NCT04592172
- Testing
- Bedtime Routine Education
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Saint Joseph's University, Philadelphia
Insomnia Disorder
Evaluating the Effects of Tasimelteon vs. Placebo in Treating Pediatric Insomnia
This is a multicenter, double-blind, randomized study to evaluate the efficacy and safety of a daily single oral dose of tasimelteon and matching placebo in male and female pediatric participants with insomnia disorder.
- Trial name
- NCT06953869
- Testing
- Tasimelteon Oral Suspension
- Where
- 35 sites in United States, Germany and 2 more
- Volunteers
- 420 people
- Sponsor
- Vanda Pharmaceuticals
Insomnia
Infant Behavioral Sleep Intervention: Comparative Efficacy
While frequent night awakenings in newborns are common and expected, an estimated 20-30% of older infants and toddlers have frequent problematic night wakings requiring parental intervention throughout the night.
- Trial name
- NCT03447665
- Testing
- Bedtime routine, Sleep schedule, Intervention (bedtime)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Indiana University
Obstructive Sleep Apnea Syndrome, Cleft Lip/Palate
A Study to Examine the Relationship Between Sleep Apnea and Cleft Lip/Palate
The study is to examine the relationship between sleep apnea and neurocognitive behaviors in children with cleft lip/palate. Describe the incidence and severity of obstructive sleep apnea in an unselected population of grade…
- Trial name
- NCT00156442
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Rochester
Apnoea, Prematurity
Automated Apnoea Detection in Preterms on Non-invasive Ventilation
The aim of this study is to monitor the frequency of apnoeas (pauses in breathing) on various methods of non-invasive respiratory support that are detected by an automated machine-learning (ML) model based on diaphragmatic…
- Trial name
- NCT07794007
- Testing
- Diaphragmatic electromyography
- Volunteers
- 30 people
- Sponsor
- King's College Hospital NHS Trust
Adolescent Health, Nutrition Behavior
The Effect of an Artificial Intelligence-Supported Health Promotion Application on the Nutrition, Exercise and Sleep Habits of Adolescents
The goal of this clinical trial is to learn if the "Smart Nurse" artificial intelligence-supported mobile application improves nutrition, exercise, and sleep behaviors in high school students aged 14-18 years.
- Conditions
- Adolescent Health, Nutrition Behavior, Physical Activity, Sleep Quality
- Trial name
- SN-ADOL-RCT (NCT07524582)
- Testing
- Smart Nurse Mobile Application
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Sleep Apnea, Obstructive
The REPOSE (Reach for Equity in Pediatric Sleep Evaluation) Navigation Intervention
This research study aims to find out the effect of REPOSE, a patient navigation intervention, on the receipt of equitable care among children with a broad range of socioeconomic and rural/urban status with Sleep Disordered…
- Trial name
- NCT06828835
- Testing
- Reach for Equity in Pediatric Obstructive Sleep Evaluation (REPOSE), Usual Care
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Medical University of South Carolina
Sleep Problems, Sleep Hygiene
Good Nights Sleep Program to Improve Child and Family Sleep
The purpose of this study is to pilot a randomized clinical trial designed to improve the sleep environments, sleep hygiene practices, and the duration and quality of sleep of children and parents in low-income families.
- Trial name
- GNSP (NCT06249217)
- Testing
- Good Nights Sleep Program
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Auburn University
Apnea, Sleep Apnea Syndromes
Oropharyngeal Exercises and Post-Stroke Obstructive Sleep Apnea
This study evaluates the feasibility and effectiveness of an oropharyngeal exercise (O-PE) regimen in treating post-stroke obstructive sleep apnea, as an alternative therapy to continuous positive airway pressure (CPAP).
- Conditions
- Apnea, Sleep Apnea Syndromes, Sleep Apnea, Obstructive, Stroke
- Trial name
- NCT04212260
- Testing
- Oropharyngeal exercises
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- Sunnybrook Health Sciences Centre
Childhood Cancer
The Effect of Walking Intervention on Sleep Related Symptom Distress in Pediatric Oncology Patients
Specific aims: Control group(2010/1~2011/6)： Aim 1: Describe the patterns of "fatigue, sleep disturbance, and pain" in children with cancer from perspectives of children and their parents over the course of one cycle (five days)…
- Trial name
- NCT01742325
- Testing
- walking
- Where
- Taiwan
- Volunteers
- 55 people
- Sponsor
- National Taiwan University Hospital
Obstructive Sleep Apnea Syndrome
Systemic Steroids Plus Antibiotics in Sleep Apnea Syndrome in Children
The purpose of this study is to investigate the effect of treatment with a steroid and antibiotic on the size of the tonsils and symptoms of children with OSAS.
- Trial name
- NCT00456339
- Testing
- Prednisolone and amoxicillin/clavulanate
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Chicago
Post-traumatic Stress Disorder
Cognitive Behavioral Treatments for Post-traumatic Stress Disorder (PTSD) Sleep Disturbance
The purpose of this study is to compare the effectiveness of two cognitive behavioral group psychotherapy interventions in controlling the subjective sleep disturbance in veterans with Post-traumatic Stress Disorder.
- Trial name
- NCT00108628
- Testing
- Imagery Rehearsal, Sleep and Nightmare Management
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- US Department of Veterans Affairs
Sleep-disordered Breathing (SDB)
Sleep-disordered Breathing and Neurocognitive Assessment in Children and Young Adults
One of main problems in the management of sleep-disordered breathing (SDB) in children and young adults is their screening, and the absence or the weak correlation between clinical symptoms and polysomnography (PSG).
- Trial name
- TRSPed (NCT04971850)
- Testing
- Sleep study
- Where
- France
- Volunteers
- 1,200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Insomnia, Depression Disorders
Effect of WBT for CI With Depression
This randomized controlled trial aims to explore the therapeutic effects of Well-Being Therapy (WBT) on patients with Chronic Insomnia accompanied by depressive symptoms.
- Trial name
- NCT06968013
- Testing
- Well-Being Therapy, Sleep Hygiene Education
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Xuanwu Hospital, Beijing
Pediatric Obstructive Sleep Apnea Syndrome
Investigating the Safety of Post-surgical Analgesics in Children With Obstructive Sleep Apnea
Every year thousands of young children with obstructive sleep apnea undergo surgery which requires them to be prescribed pain medication.
- Trial name
- NCT01680939
- Testing
- Morphine, Ibuprofen
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Diabetes
Sleep Intervention for Youth With Type 1 Diabetes
Sleep intervention for youth with diabetes
- Trial name
- NCT01739712
- Testing
- Sleep extension, Fixed Sleep Duration
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- University of Arizona