Clinical trials: ED
Respiratory Tract Infections, Influenza, Human
Rapid Diagnostics for Upper Respiratory Infections in the Emergency Department
This is a randomized clinical trial to assess the effect of rapid, near point-of-care testing for multiple common respiratory viruses and bacteria on antibiotic and anti-influenza medication use in emergency department (ED)…
- Conditions
- Respiratory Tract Infections, Influenza, Human, Common Cold
- Trial name
- URIDxED (NCT02957136)
- Testing
- Rapid respiratory pathogen nucleic acid amplification test
- Where
- United States
- Volunteers
- 194 people
- Sponsor
- University of California, Davis
Syncope
Diagnostic Yield of an Ambulatory Patch Monitor in Unexplained Emergency Department Syncope: A Pilot Study (PATCH-ED)
Syncope is a common Emergency Department (ED) presentation but the underlying diagnosis is not apparent in 60% of patients after assessment and serious adverse event rate is 7% at one month with most having acute cardiovascular…
- Trial name
- PATCH-ED (NCT02683174)
- Testing
- Novel ambulatory patch (ZIO® XT Patch), BNP and hs-troponin I at 0 and 3 hours post ED attendance
- Where
- United Kingdom
- Volunteers
- 86 people
- Sponsor
- NHS Lothian
Aging
Reducing Potentially Inappropriate Medication Prescribing for Older Patients in the ED
This research is being conducted to learn which implementation strategy of EQUIPPED is most effective to improve prescribing practices of ED providers toward older Veterans and determine the factors influencing implementation of…
- Trial name
- EQUIPPED (NCT04004936)
- Testing
- EQUIPPED with Active Feedback, EQUIPPED with Passive Feedback
- Where
- 4 sites in United States
- Volunteers
- 74 people
- Sponsor
- VA Office of Research and Development
Asthma
Trial of One Versus Two Doses of Dexamethasone for Pediatric Asthma Exacerbation
Comparing one versus two doses of oral dexamethasone for the treatment of asthma in the pediatric emergency department.
- Trial name
- R2D2 (NCT02725008)
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Geoffrey W Jara-Almonte
Asthma
Albuterol Versus Xopenex in Treatment of Acute Asthma in the Emergency Department (ED)
The purpose of this study is to determine in a large, double-blind, randomized, prospective pediatric clinical trial whether the use of continuous levalbuterol (Xopenex) in addition to standard emergency department treatment for…
- Trial name
- Xopenex (NCT00585039)
- Testing
- xopenex
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Phoenix Children's Hospital
Emergencies
Kiosk-Model Self-Triage System in the Pediatric Emergency Department
An audio-assisted self-triage kiosk in the Pediatric Emergency Department (ED) is expected to significantly reduce triage times, without any sacrifice of the quality of information that would be obtained by nurse-initiated triage.
- Trial name
- NCT01515488
- Testing
- Nurse-initiated triage, Self-triage kiosk
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Valleywise Health
Children Who Present to the ED With Minor Febrile Illnesses
Video Discharge Instructions for Fever and ED Recidivism
To evaluate the effect of video discharge instructions on return visits to the ER or ED within 72 hours of the original visit for children with febrile illnesses.
- Trial name
- NCT01655251
- Testing
- Intervention
- Where
- 2 sites in United States
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Connecticut Children's Medical Center
Presyncope, Arrhythmias, Cardiac
The IPED (Investigation of Palpitations in the ED) Study
Palpitations (noticeable pounding, fluttering or irregular heart beat) and pre-syncope (near blackout) are common ED problems sometimes due to an abnormal cardiac rhythm.
- Conditions
- Presyncope, Arrhythmias, Cardiac, Tachycardia, Supraventricular, Atrial Fibrillation
- Trial name
- IPED (NCT02783898)
- Testing
- AliveCor Heart Monitor
- Where
- 10 sites in United Kingdom
- Volunteers
- 243 people
- Sponsor
- NHS Lothian
Depressive Disorder, Major
A Randomized Controlled Trial of PCIT-ED for Preschool Depression
Parent Child Interaction Therapy Emotion Development (PCIT-ED) will be conducted with a sample of preschoolers who exhibit symptoms of depression compared to a wait list (WL) control after which participants will receive the…
- Trial name
- NCT02076425
- Testing
- PCIT-ED
- Where
- United States
- Volunteers
- 229 people
- Sponsor
- Washington University School of Medicine
Penicillin Allergy, Pediatric Emergency Medicine
Oral Challenge in the Pediatric ED
Our primary objective was to demonstrate the feasibility of utilizing a novel penicillin allergy questionnaire in the PED to identify a low-risk group of patients who will complete an oral challenge in the PED to test for an…
- Trial name
- OPEN (NCT03404804)
- Testing
- Amoxicillin
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Medical College of Wisconsin
Asthma
Comparison of Nebulizers in ED in Pediatric Asthma Patients
The primary objective will be, in an open-label randomized trial, a comparison of emergency department (ED) length of stay (LOS) between children experiencing acute asthma treated with two different nebulizers.
- Trial name
- NCT01951378
- Testing
- Hudson RCI® nebulizer, NebuTech® HDN® nebulizer, Albuterol
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Seton Healthcare Family
Pediatric Disorder
A Comparison of Accuvein to Standard IV Access in Children 0 to 24 Months of Age in the Pediatric ED
Obtaining intravenous (IV) access in children under the age of 2 years is difficult, especially in the emergency department (ED) where the children can be frightened, dehydrated and ill.
- Trial name
- NCT02381392
- Testing
- Accuvein AV400
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Accident, Traffic
Tiny Cargo, Big Deal! An ED-Based Study of Child Passenger Safety Behaviors
This study involves an emergency department (ED)-based intervention utilizing Motivational Interviewing (MI) techniques and patient-centered eHealth materials (e.g., a tailored, mobile-friendly website and text messages) to…
- Trial name
- NCT04238247
- Testing
- Tiny Cargo, Big Deal/Abróchame Bien, Cuídame Bien (TCBD/ABCB) Basic Intervention, Tiny Cargo, Big Deal/Abróchame Bien, Cuídame Bien (TCBD/ABCB) Enhanced Intervention
- Where
- United States
- Volunteers
- 513 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Intravenous Administration
Clinical Trial Testing Buzzy Bee vs Vapocoolant During IV Placement
The purpose of this study is to compare the anxiety and pain levels of patients when using Buzzy with ice, Vapocoolant, and placebo when inserting IV's line for IV fluids and/or phlebotomy in pediatric patients in the pediatric…
- Trial name
- NCT06182631
- Testing
- Buzzy Bee, Vapocoolent
- Where
- United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Bronchiolitis
Heliox-Driven Racemic Epinephrine in Treatment of Bronchiolitis in Pediatric ED Patients
The purpose of this study is to assess whether children with moderate to severe bronchiolitis treated with standard racemic epinephrine therapy via 70:30 helium-oxygen (heliox) driven nebulization will have improvements in…
- Trial name
- NCT00116584
- Testing
- heliox, oxygen
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Pain
Nebulized Sub-dissociative Dose Ketamine at Three Different Dosing Regimens for Treating Acute Pain in the Pediatric ED
In the situation when intravenous access is not readily available or unobtainable, sub-dissociative dose ketamine can be administered via intranasal route (IN).
- Trial name
- NCT03950817
- Testing
- Nebulized Sub-dissociative Dose Ketamine at either 0.75 mg/kg, Nebulized Sub-dissociative Dose Ketamine at 1 mg/kg, Nebulized Sub-dissociative Dose Ketamine at 1.5 mg/kg.
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Antonios Likourezos
Autism Spectrum Disorder
Satisfaction Rates Among Parents of Children With Autism in the ED
This study is a randomized controlled trial utilizing a patient-centered questionnaire distributed to parents of children with autism.
- Trial name
- ASD (NCT02675933)
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Seton Healthcare Family
Multimorbidity
Discharge Information and Support for Patients Receiving Outpatient Care in the Emergency Department
The Veterans' Health Administration (VHA) is committed to improving primary care through the implementation of Patient Aligned Care Teams (PACTs).
- Trial name
- DISPO ED (NCT01717976)
- Testing
- DISPO ED
- Where
- United States
- Volunteers
- 513 people
- Sponsor
- VA Office of Research and Development
Pain Management
IBUPAP Study for Pain Management in Children
Current literature supports ibuprofen and APAP are the most commonly used analgesics in the pediatric ED for acute traumatic/non-traumatic pain.
- Trial name
- NCT03088800
- Testing
- Ibuprofen, APAP
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Antonios Likourezos
Depressive Disorder, Violence
Text-Message-Based Depression Prevention for High-Risk Youth in the ED
The purpose of this randomized controlled study is to evaluate acceptability and feasibility, and to gather preliminary data about efficacy, of "iDOVE," a brief emergency department introductory session + longitudinal automated…
- Trial name
- iDOVE (NCT02332239)
- Testing
- iDOVE Intervention (ED+text), Control (EUC)
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Rhode Island Hospital