Clinical trials: EOS
Eosinophilic Gastroenteritis, Dyspepsia
Montelukast in the Treatment of Duodenal Eosinophilia
This is a single site study of the effect of montelukast on eosinophil and mast cell counts and activation in the lining of the duodenum in 24 children with dyspepsia in association with duodenal eosinophilia in association with…
- Trial name
- NCT00148603
- Testing
- montelukast
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Eosinophilia, Hypereosinophilic Syndrome
A Longitudinal Study of Familial Hypereosinophilia (FE): Natural History and Markers of Disease Progression
Eosinophils are a type of white blood cell. Elevated eosinophil levels can damage the heart, nerves, and other organs, in the syndrome known as hypereosinophilic syndrome (HES).
- Trial name
- NCT00091871
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Asthma
Phenotyping Responses to Systemic Corticosteroids in the Management of Asthma Attacks
This observational study compares the phenotypic variability (clinical and biological) in treatment response to systemic corticosteroids according to the blood eosinophil count and FeNO in physician-diagnosed ≥12-year-old…
- Trial name
- PRISMA (NCT05870215)
- Testing
- Visit 1: Clinical exam and questionnaires, Visit 1: Respiratory physiology, Visit 1: Inflammometry
- Where
- Canada
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Perennial Allergic Rhinitis
Levocetirizine Effect on Nasal Nitric Oxide and Nasal Eosinophils in Subjects With Perennial Allergic Rhinitis
The purpose of this study is to noninvasively measure the anti-inflammatory effect of levocetirizine after two weeks of treatment in allergic rhinitis subjects.
- Trial name
- NCT00894231
- Testing
- levocetirizine (Xyzal)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- AAADRS Clinical Research Center
Behçet's Disease
Behçet's Disease and Eosinophil Cationic Protein
Eosinophil cationic protein (ECP) is a matrix protein of eosinophils and has been reported to reflect eosinophil activity. Few studies have examined the role of eosinophils in the pathogenesis of Behçet's disease.
- Trial name
- NCT01584778
- Testing
- eosinophil cationic protein
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Eosinophilic Esophagitis, Gastroesophageal Reflux Disease
Morphological Markers of Gastroesophageal Reflux Disease (GERD)
The purpose of this project is to learn more about a new and promising way to diagnose acid reflux disease using a very high-powered microscope.
- Trial name
- NCT01921686
- Testing
- Sample collection and Questionnaire
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Eosinophilic Esophagitis, Gastritis
Data Bank for Eosinophilic Disorders
The purpose of this study is to conduct a translational study in patients with primary eosinophil associated gastrointestinal disorders [EGID] (e.g.
- Conditions
- Eosinophilic Esophagitis, Gastritis, Enteritis, Eosinophilic Colitis
- Trial name
- NCT00267475
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Marc Rothenberg
Asthma
Role of Eosinophils in the Proliferation of Airway Smooth Muscle (ASM) Cells
Being a key player in Asthma, eosinophils constitute a potential target to interfere with the series of biological events leading to Asthma pathogenesis.
- Trial name
- NCT01082952
- Where
- Saudi Arabia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- King Saud University
Eosinophilic Gastrointestinal Disease Eosinophilic Inflammatory Disease, Food Allergy
Data and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic Disorders
The purpose of this study is to elucidate the mechanisms underlying eosinophil growth, survival, migration, and function and to investigate and further characterize the pathophysiology of, clinical manifestations of, and spectrum…
- Trial name
- NCT00267501
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati