Clinical trials: Early Child Development
Limb Deficiencies
Early Prosthetics in Children With Upper Limb Deficiency
For children with congenital upper limb deficiency, introduction of the prosthesis is guided by clinical experience rather than by Evidence Based Medicine.
- Trial name
- EARLIMB (NCT04851600)
- Testing
- prosthesis
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Lille
Child Development
A Home Visiting Program for Pregnant Youth to Promote Early Brain Development II
Home visiting programs for pregnant women aiming to improve mother-infant relationship has received worldwide attention in the past 30 years.
- Trial name
- NCT04362098
- Testing
- Home visiting Program for Young Pregnant Women
- Where
- Brazil
- Volunteers
- 167 people
- Sponsor
- University of Sao Paulo
Pollution; Exposure, Neurodevelopmental Disorders
Air Pollution and Development in the Boricua Youth Study
This study seeks to understand the relationship between prenatal maternal air pollution exposure and offspring risk for ADHD and examine two potential -modifiable- mechanisms: prenatal maternal inflammation and offspring sleep…
- Trial name
- NCT05368493
- Testing
- MRI task
- Where
- 2 sites in United States, Puerto Rico
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Health Knowledge, Attitudes, Practice
Promoting Child Development Practices in the First Year of Life Through a Video Administered at Two Different Times
There is an increasing need for parenting programs aimed at promoting parent-child interaction. A variety of interventions have been proposed.
- Trial name
- NCT02120430
- Testing
- Video
- Where
- Italy
- Volunteers
- 105 people
- Sponsor
- IRCCS Burlo Garofolo
Autism Spectrum Disorder
Early Intervention and Autism: Transformation From Research to Practice Through a Competency Based Model
This study evaluates the effect of a competency based model on program quality in Swedish preschools for Children with autism spectrum disorder (ASD).
- Trial name
- AUT-TID (NCT03634761)
- Testing
- Competency based model, Comprehensive program
- Where
- 2 sites in Sweden
- Volunteers
- 17 people
- Sponsor
- Stockholm University
School Readiness, School Environment
Every Newborn Reach Up Early Education Intervention for All Children Education (ENREACH) Education
The goal of the project is to assess the scale-up of the program, focusing on improving school readiness among preschool children, enhancing capacity building for parents and teachers, and utilizing a cluster randomized…
- Trial name
- ENREACH-ED (NCT06890156)
- Testing
- ENREACH child-parent-teacher triad
- Where
- Bangladesh
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Critical Illness
Development of a Modified Pediatric Early Warning Score: a French Prospective Multicentre Regional Study
Children are admitted in intermediate units when the severity requires continuous monitoring. In France, Resources allocated to intermediate units are determined from lists of diagnoses and associated acts to additional budget.
- Trial name
- NCT02304341
- Where
- 7 sites in France
- Volunteers
- 3,016 people
- Sponsor
- University Hospital, Lille
Early Intervention (Education)
Early Support From Birth Onwards: ZEPPELIN
ZEPPELIN (Zurich Equity Prevention Project with Parents Participation and Integration) is a longitudinal, randomized controlled intervention study.
- Trial name
- ZEPPELIN (NCT02882763)
- Testing
- Parents As Teachers (PAT)
- Where
- Switzerland
- Volunteers
- 213 people
- Sponsor
- University of Applied Sciences of Special Needs Education
Early Childhood, Neurodevelopment, Early Childhood, Anthropometry
Environmental Pollutants in Pregnancy - IoMumNEXT
Globally 12.6 million people, including 1.7 million children under the age of 5, die each year from environmental-related illnesses.
- Trial name
- IoMumNEXT (NCT06226311)
- Testing
- Data collection, Diagnostic Test: Urinary
- Where
- Portugal
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Autism Spectrum Disorder, Infant Development
Experimental Techniques for Early Identification of Autism
This project deals with essential challenges in the context of Autism Spectrum Disorder, benefiting from a longitudinal design in infancy and a cutting-edge electroencephalogram/eye-tracking integrated approach.
- Trial name
- NCT05712512
- Testing
- Neurodevelopmental assessment, Electrophysiological and eyetracking recordings
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Eugenio Medea
Functional Constipation, Emotional Problems
Early Screening of Emotional, Behavioral and Autism Spectrum Disorders in Children With Functional Constipation.
A significant group of children with functional constipation (FC) continues to have symptoms despite recommended standard therapy. Underlying psychiatric problems could explain therapy resistance.
- Conditions
- Functional Constipation, Emotional Problems, Behavioural Problems, Developmental Disorder
- Trial name
- NCT03614000
- Testing
- Screening Questionnaires
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Universitair Ziekenhuis Brussel
Breast Feeding, Parenting
Doula Home Visiting Randomized Trial
The purpose of this randomized controlled trial is to examine whether evidence-based home visiting programs enhanced by doula services have effects on positive parenting practices, breastfeeding, and child and maternal health…
- Conditions
- Breast Feeding, Parenting, Child Development, Depression, Postpartum
- Trial name
- NCT01947244
- Testing
- Doula Home Visiting, Case management
- Volunteers
- 312 people
- Sponsor
- University of Chicago
Autism Spectrum Disorder
Autism Access Link for Early Referral and Treatment
Autism Access Link for Early Referral and Treatment [ALERT], the intervention proposed in this application, is a novel state-wide referral and case management platform that PCPs can activate to ensure that a child with suspected…
- Trial name
- Autism ALERT (NCT04861740)
- Testing
- Autism ALERT, Screening Intervention
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Child Development
Shanghai Children's Health, Education and Lifestyle Evaluation, Preschool (the SCHEDULE-P Study)
Shanghai is one of pilot areas for the early education of 3-6 years old infants in China. Shanghai Municipal Education Commission has been actively exploring more effective early education guidance methods.
- Trial name
- NCT04037761
- Where
- China
- Volunteers
- 20,899 people
- Sponsor
- Sijia Gu
Child Development
The Effects of Early-life Environmental and Behavioral Factors on Child Growth and Development
The Shanghai Sleep Birth Cohort Study (SSBC) is a prospective observational study investigating the sleep condition of women in their third trimester and children from the age of 42 days to 6 years.
- Trial name
- SSBC (NCT04314466)
- Where
- China
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Autism
Interactive Massage Intervention in Toddlers With Autism Spectrum Disorder
This randomized controlled trial aims to evaluate the efficacy of a 3-month maternal interactive massage intervention in toddlers aged 18-24 months with autism spectrum disorder (ASD).
- Trial name
- IMI-ASD (NCT07876245)
- Testing
- Maternal Interactive Massage, Behavioral
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Autism
Combined Effects of Early Behavioral Intervention and Propranolol on ASD
The purpose of this study is to explore the effects of propranolol in combination with early intensive behavioral intervention on social interaction, and secondarily on language, anxiety, adaptive behaviors, and global function…
- Trial name
- NCT02428205
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Missouri-Columbia
Violence, Gender-Based, Violence, Domestic
Responsible Engaged and Loving (REAL) Fathers Intervention Evaluation
The goal of this stepped-wedge cluster randomized control trial is to assess whether a Ugandan community-based intervention for young fathers (ages 18-25 years) of children ages 0-3 years impacts fathers' knowledge, attitudes…
- Conditions
- Violence, Gender-Based, Violence, Domestic, Violence, Sexual, Violence, Physical
- Trial name
- NCT06100679
- Testing
- Responsible Engaged and Loving (REAL) Fathers Initiative
- Where
- 4 sites in Uganda
- Volunteers
- 4,728 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Child Development, Developmental Disabilities
Testing the Effectiveness of Telephone-based Early Childhood Developmental Screening
The purpose of this research study is to test the effectiveness of telephone-based early childhood developmental screening and care coordination, compared to usual care in a primary care pediatrics clinic.
- Conditions
- Child Development, Developmental Disabilities, Ambulatory Care, Screening
- Trial name
- NCT02495025
- Testing
- Telephone-based developmental screening and care coordination
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Child Development, Child Behavior
Achieving Sustained Early Child Development Impacts at Scale: A Test in Kenya
An estimated 43% of children under age 5 in low- and middle-income countries (LMICs) experience compromised development due to poverty, poor nutrition, and inadequate psychosocial stimulation.
- Conditions
- Child Development, Child Behavior, Language, Child
- Trial name
- NCT06140017
- Testing
- Msingi Bora responsive parenting and family wellbeing program
- Where
- Kenya
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Southern California