Clinical trials: Early Child Development
Tuberous Sclerosis Complex
Early Biomarkers of Autism in Infants With Tuberous Sclerosis Complex (TSC)
The investigators are enrolling 3-12 month old infants with a diagnosis of tuberous sclerosis complex (TSC) for a new study on early markers of autism.
- Trial name
- NCT01780441
- Where
- 5 sites in United States
- Volunteers
- 166 people
- Sponsor
- Boston Children's Hospital
Language Delay, Developmental Language Disorders
Effectiveness of Early Parent-Based Language Intervention
The purpose of the study is to examine the effectiveness of a highly-structured parent-based language intervention group program for two-year-old children with language delay.
- Trial name
- NCT00625261
- Testing
- Heidelberg Parent-based Language Intervention HPLI
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Heidelberg University
Autism Spectrum Disorder, Social Communication Disorder
Virtual Group Social ABCs - Multi-site Randomized Controlled Trial
The goal of this randomized control trial is to test the efficacy of the Social ABCs 6 week, group-based model using a virtual delivery platform.
- Conditions
- Autism Spectrum Disorder, Social Communication Disorder, Autism or Autistic Traits, Autism Spectrum Disorder With Impaired Functional Language
- Trial name
- NCT05663970
- Testing
- VG Social ABCs
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Tuberous Sclerosis, STXBP1 Encephalopathy With Epilepsy
Gait in Rare Diseases
The aim of this pilot study is to explore whether the knowledge and experience gained during the T-GaiD project (Treatment of Gait Disorders in Dravet Syndrome - NCT03857451) can be transferred to other populations with similar…
- Trial name
- GAGA (NCT05161494)
- Where
- Belgium
- Volunteers
- 41 people
- Sponsor
- Universiteit Antwerpen
Intimate Partner Violence (IPV)
Familia Imara: A Parenting Program to Reduce Family Violence in Tanzania
This cluster-randomized controlled trial will evaluate the effectiveness, implementation, and scalability of Familia Imara, a group-based, couples-focused, community health worker (CHW)-delivered parenting program, on reducing…
- Trial name
- NCT07574567
- Testing
- Familia Imara
- Where
- Tanzania
- Volunteers
- 6,216 people, healthy volunteers welcome
- Sponsor
- Saini Das
Autism
Early Pharmacotherapy Aimed at Neuroplasticity in Autism : Safety and Efficacy
The purpose of this study is to determine the efficacy, safety, and population pharmacokinetics and determinants of drug responses to buspirone in children with autism using a randomized, double blind, cross over study in…
- Trial name
- NCT00166621
- Testing
- Buspirone
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Chugani, Diane C.
Child Rearing, Adolescent Development
Follow-up of Families in Early Preventive Intervention
This project supports the post-third-grade assessment of 693 children and their families who were enrolled in a randomized trial of a program of prenatal and infancy home visitation by nurses that was epidemiologically and…
- Conditions
- Child Rearing, Adolescent Development, Reproductive Behavior, Risk Reduction Behavior
- Trial name
- MemphisYear9 (NCT00438516)
- Testing
- nurse home visitation
- Where
- United States
- Volunteers
- 627 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Autism Spectrum Disorder, Parents
Mindfulness Training and Parent-coaching Interventions for Autism Spectrum Disorder
Caregivers of children with autism spectrum disorder (ASD) report higher levels of depression and distress than caregivers of typically developing children as well as children with other developmental disabilities.
- Conditions
- Autism Spectrum Disorder, Parents, Stress
- Trial name
- NCT03889821
- Testing
- Parent-implemented Early Start Denver Model, Mindfulness Based Stress Reduction
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Vanderbilt University Medical Center
Autism Spectrum Disorders
Effectiveness of Early Intervention in an Underserved Population
The purpose of this study is to test the applicability of a caregiver-implemented autism intervention protocol to a deliberately recruited low-income, underserved population.
- Trial name
- ESI-CO (NCT01250938)
- Testing
- ESI - Community Outreach
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- University of California, Los Angeles
Early Child Development
Testing Means to Scale Early Childhood Development Interventions in Rural Kenya
This study aims to experimentally test the effectiveness and cost-effectiveness of competing models of delivery of an Early Childhood Development (ECD) intervention in rural Kenya to determine how to maximize their reach to…
- Trial name
- NCT03548558
- Testing
- Group sessions, Group+Home sessions, Booster sessions
- Where
- United States
- Volunteers
- 1,152 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Prematurity
Different Intervention Models of Premature Infants Based on the ICF Biopsychosocial Model
Prematurity is an important risk factor for delayed neuropsychomotor development. The main objective of this study is to analyze the impact of different intervention models on the neuropsychomotor development of premature babies…
- Trial name
- NCT05989438
- Testing
- Orientations for families, Professional stimulation more orientations for families.
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Federal University of Health Science of Porto Alegre
Dietary Behaviors, Child Growth and Development
The Growing Well Study
What are the study aims? To understand more about eating habits and age-appropriate food/drink portion sizes of children aged 6 months-5 years old, and how this affects their growth and dental health.
- Conditions
- Dietary Behaviors, Child Growth and Development, Dental Health, Dietary Intakes
- Trial name
- GWS (NCT07698158)
- Testing
- Dietary intake and patterns (including vegetarian, vegan, and dairy-free diets)
- Where
- 6 sites in United Kingdom
- Volunteers
- 1,890 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Development Delay
Parent-Child Interaction in Garding Activities for Early Intervention Preschool Children
Post-COVID-19, children's reduced interaction with nature has hindered their sensory development, particularly affecting those with developmental delays.
- Trial name
- NCT06507358
- Testing
- Parent-Child Interaction group
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Parent-Child Relations, Parenting
CenteringParenting Clinical Intervention on Kindergarten Readiness in Early Childhood
Disparities in health begin in early childhood. Early life experiences influence brain development and have significant implications on future health and developmental outcomes.
- Conditions
- Parent-Child Relations, Parenting, Child Development, Child Behavior
- Trial name
- NCT03641092
- Testing
- CenteringParenting Intervention, Routine Well Child Care
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Head Start Participation
The 2021-2022 Study of Family and Staff Well-Being in Head Start AIAN FACES Programs
The 2021-2022 Study of Family and Staff Experiences in American Indian and Alaska Native Head Start Family and Child Experiences Survey Programs (the 2021-2022 Study) builds on AIAN FACES 2019, a national study of children and…
- Trial name
- NCT06510218
- Where
- United States
- Volunteers
- 560 people
- Sponsor
- Mathematica Policy Research, Inc.
Autism Spectrum Disorder
How Simplified Language Affects Comprehension and Learning in Young Autistic Children
The long-term study goal is to experimentally evaluate the components (and likely active ingredients) of early language interventions for young children with ASD.
- Trial name
- PALS (NCT05707923)
- Testing
- Linguistic simplification
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Michigan State University
Dietary Assessment
Early Childhood Dietary Assessment Study
The goal of this crossover randomized controlled trial is to develop a proxy reporting protocol for a traditional 24-hour dietary recall (24HR) and an ecological momentary assessment (EMA) assisted 24-HR for use among children…
- Trial name
- ECDAS (NCT07227272)
- Testing
- Ecological Momentary Assessment, Traditional 24-hour dietary recall
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Autism Spectrum Disorder (ASD)
Promoting Physical Activity Among Young Children With Autism
Higher amounts of physical activity are linked to multiple health benefits including improved cognition, academic success, and classroom behavior for children.
- Trial name
- NCT07747129
- Testing
- Wellness Enhancing Physical Activity for Young Children (WE PLAY), Non-Physical Activity Online Training
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- Northeastern University
Early Childhood Professional Development
Professional Development Tools to Improve the Quality of Infant and Toddler Care
Mathematica Policy Research, funded by OPRE, ACF, DHHS, will conduct a field test of We Grow Together: The Q-CCIIT Professional Development System.
- Trial name
- Q-CCIIT PD (NCT03433872)
- Testing
- We Grow Together: The Q-CCIIT Professional Development System
- Volunteers
- 475 people, healthy volunteers welcome
- Sponsor
- Mathematica Policy Research, Inc.
Autism Spectrum Disorder
Training Early Social Language in Autism
The aim of the study is to determine whether a targeted behavioral intervention can lead to both changes in early communication skills and in neural responses in toddlers and preschoolers with autism.
- Trial name
- TESLA (NCT03427138)
- Testing
- Jasper, Parent Education
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus