Clinical trials: Early Life Adversity
Early Life Adversity, Caregiver Stress
The Resilience Clinic Evaluation
Early life adversity can affect children's physical and mental health. The Resilience Clinic is a support program for young children and their caregivers who have been exposed to significant adversity, aiming to prevent the…
- Trial name
- NCT05690256
- Testing
- Resilience Clinic, Enhanced primary care
- Where
- 4 sites in United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Depression
Positive Affect Treatment for Adolescents With Early Life Adversity
Youth exposed to early life adversity (ELA) are known to be at greater risk for depression and suicidality and account for almost half of the youth suffering from psychiatric diseases today.
- Trial name
- PAT4ELA (NCT06273137)
- Testing
- Positive affect treatment, Supportive psychotherapy (SUP)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Early Life Adversity, Caregiver Stress
Collaborative Approach to Examining Adversity and Building Resilience Study
To examine the behavioral, psychosocial, and biologic impact of resilience-promoting interventions associated with primary care.
- Trial name
- CARE (NCT05259436)
- Testing
- Caregiver-child Intervention, Enhanced Primary Care
- Where
- 4 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Early Life Adversity, Microbiome, Human
Between the Belly and the Brain: Distorted Gut-brain Crosstalk in Early-life Adversity
The goal of this observational study is to learn about the effects of early-life adversity (ELA) on the composition of children's microbiome and on their psychosocial functioning.
- Conditions
- Early Life Adversity, Microbiome, Human, Anxiety Symptoms, Depressive Symptoms
- Trial name
- BellyBrain (NCT06922773)
- Testing
- Completion of questionnaires; child psychiatric screening; faecal sample analysis
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Universitair Ziekenhuis Brussel
Child Development
Examining the Role of Pain in the Link Between Early Childhood Adversity and Psychopathology
The goal of this study is to investigate the role of physical pain in the link between childhood adversity and later psychopathology.
- Trial name
- NCT06445712
- Testing
- Parental Support Cold Pressor Task
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Washington University School of Medicine
Adolescents With Early Life Stress
Augmented Mindfulness Training for Resilience in Early Life
This project aims to determine whether neurofeedback augmented mindfulness intervention increases the plasticity in brain areas affected by exposure to early life adversity in youth.
- Trial name
- A-MindREaL (NCT04053582)
- Testing
- AMT
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Emotional Dysfunction, Early Life Stress
Dyadic Neurofeedback for Emotion Regulation in Youth With Maternal Adversity
This study will examine the effect of a real-time functional magnetic resonance imaging (fMRI) dyadic neurofeedback protocol with mothers and their adolescent daughters.
- Trial name
- NCT04964726
- Testing
- Real-time fMRI dyadic neurofeedback
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University Center for Health Sciences