Clinical trials: Effectiveness
Analgesia, Post Caserean
Piroxicam Versus Diclofenac for Post Caesarean Section Analgesia
Multimodal analgesic combination of pentazocine-diclofenac has been found to be superior to pentazocine-piroxicam and was associated with a higher level of maternal satisfaction.
- Trial name
- NCT06943092
- Testing
- Piroxicam group, Diclofenac group
- Where
- Nigeria
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Federal Teaching Hospital Abakaliki
Schizophrenia, Psychotic Disorders
CAFE Comparison of Atypicals in First Episode of Psychosis
The purpose of this study is to compare the effectiveness, tolerability, and efficacy of the currently available atypical antipsychotic drugs olanzapine (2.5-20 mg/day), quetiapine (100-800 mg/day) and risperidone (0.5-4 mg/day)…
- Conditions
- Schizophrenia, Psychotic Disorders, Mental Health, Mental Disorders
- Trial name
- NCT00034892
- Testing
- Olanzapine, risperidone
- Where
- 26 sites in United States, Canada
- Sponsor
- AstraZeneca
Infantile Colic
An Infant Formula Trial on Dietary Management of Infantile Colic
A randomised, double blind, controlled, multi-centre study to assess the efficacy of an infant formula in the dietary management of infantile colic.
- Trial name
- NCT03329222
- Testing
- Specific hydrolysed proteins, Standard cow's milk with prebiotics mixture
- Where
- 2 sites in Singapore, Thailand
- Volunteers
- 5 people
- Sponsor
- Danone Asia Pacific Holdings Pte, Ltd.
Emotional Dysregulation, Externalizing Problems
Assessing Real Life Effectiveness of Treatment in Neurodevelopmental Disorders
The goal of this observational study is to learn if and how pharmacological and psychotherapeutic group treatments can treat clinical symptoms of children and adolescent patients with ADHD.
- Conditions
- Emotional Dysregulation, Externalizing Problems, Oppositional Defiant, Conduct Disorder
- Trial name
- ALERT (NCT07273695)
- Testing
- methyphenidate, Group psychological treatment
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- IRCCS Eugenio Medea
Asthma
Efficacy and Safety of 2 Doses of Tiotropium Respimat® Compared to Placebo in Children With Moderate Persistent Asthma
The overall purpose of the trial is to evaluate efficacy and safety of tiotropium inhalation solution delivered via Respimat® inhaler (2.5 mcg and 5 mcg once daily in the evening) over 48 weeks, compared to placebo, in children…
- Trial name
- NCT01634139
- Testing
- Tiotropium low dose QD, Tiotropium high dose QD
- Where
- 79 sites in United States, Bulgaria and 14 more
- Volunteers
- 403 people
- Sponsor
- Boehringer Ingelheim
Benzodiazepine Refractory Status Epilepticus
Established Status Epilepticus Treatment Trial
The primary objective is to determine the most effective and/or the least effective treatment of benzodiazepine-refractory status epilepticus (SE) among patients older than 2 years.
- Trial name
- ESETT (NCT01960075)
- Testing
- Fosphenytoin, Levetiracetam, Valproic acid
- Where
- 65 sites in United States
- Volunteers
- 478 people
- Sponsor
- University of Virginia
Mild to Moderate Anterior Mandibular Segment Crowdind
Acceleration of Orthodontic Tooth Movement
EVALUATION OF EFFICACY OF LOCALLY INJECTED Vitamin D3 (calcitriol or 1.25 dihidroxicolecalciferol) IN ACCELERATING ORTHODONTIC MOVEMENT Design: A randomized, controlled, crossover, double-blind clinical study including Eighteen…
- Trial name
- NCT05560919
- Testing
- Dihydroxycholecalciferols, dimethyl sulfoxide, serum
- Where
- Syria
- Volunteers
- 18 people
- Sponsor
- Latakia University
Attention Deficit Hyperactivity Disorder
Effectiveness Study of Videoconferencing on Teaching Parent Training Skills to Parents of Children With Attention Deficit Hyperactivity Disorder (ADHD)
The purpose of this study is to evaluate the effectiveness of group parent training taught through videoconferencing on ADHD treatment via a comparison between participants using traditional face-to-face parent training sessions…
- Trial name
- NCT01161719
- Testing
- parent training
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of California, Davis
Severe Rotavirus Gastroenteritis
Efficacy and Safety of a Pentavalent Rotavirus Vaccine (BRV-PV) Against Severe Rotavirus Gastroenteritis in Niger
The study is a double-blinded, randomized, placebo-controlled, trial with two groups of infants receiving vaccine or placebo to assess the efficacy and safety of BRV-PV.
- Trial name
- ROSE (NCT02145000)
- Testing
- Rotavirus vaccine (BRV-PV)
- Where
- Niger
- Volunteers
- 6,586 people, healthy volunteers welcome
- Sponsor
- Epicentre
Oral Treatment of Acute Uncomplicated Plasmodium Falciparum Malaria
Evaluation of Fosmidomycin and Piperaquine in the Treatment of Acute Falciparum Malaria
The objective of this study is to explore the role of fosmidomycin and piperaquine as non-artemisinin-based combination therapy for acute uncomplicated Plasmodium falciparum when administered over three days.
- Trial name
- FOSPIP (NCT02198807)
- Testing
- Fosmidomycin-Piperaquine
- Volunteers
- 100 people
- Sponsor
- Jomaa Pharma GmbH
Dental Caries
Effectiveness of Fissure Sealant and Topical Fluoride Application in Preventing Dental Caries
Nearly half of the 12-year-old children in China have dental caries (tooth decay) and most of the lesions are in the fissures of the first permanent molars.
- Trial name
- NCT01446107
- Testing
- placement of fissure sealant, fluoride varnish, silver fluoride
- Where
- China
- Volunteers
- 502 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Autism Spectrum Disorder, Parent-Child Relations
Pilot Testing of a Mobile Phone App-based Intervention for Parents of Children With Autism Spectrum Disorder (ASD)
The objective of this study is to conduct a pilot randomised controlled trial (RCT) evaluating the feasibility, acceptability, and preliminary efficacy of a 6-week mobile app-based intervention in empowering and supporting…
- Trial name
- NCT05927207
- Testing
- TRIP
- Where
- Hong Kong
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Hemiplegia and Hemiparesis, Cerebral Palsy Infantile
Effectiveness of the Functional Hand Splint and Specific Tasks in the Domiciliary Environment Applied to Children With Unilateral Cerebral Palsy
The main objective: To determine the effectiveness of a treatment that combines the application of a functional upper limb orthosis together with a home-based program of specific tasks in children with unilateral cerebral palsy…
- Trial name
- NCT03282422
- Testing
- Home-based protocol in specific tasks, Upper-limb splint
- Where
- 2 sites in Spain
- Volunteers
- 33 people
- Sponsor
- Universidad San Jorge
Achondroplasia
A Study to Evaluate the Efficacy and Safety of Infigratinib in Children and Adolescents With Achondroplasia
This is a Phase 3, multicenter, double-blind, randomized, placebo-controlled study to evaluate the efficacy and safety of infigratinib in children and adolescents with achondroplasia (ACH) who have completed at least 26 weeks of…
- Trial name
- PROPEL3 (NCT06164951)
- Testing
- Infigratinib 0.25 mg/kg/day
- Where
- 27 sites in United States, Argentina and 8 more
- Volunteers
- 114 people
- Sponsor
- QED Therapeutics, a BridgeBio company
Neonatal Abstinence Syndrome
Treatment of Neonatal Abstinence Syndrome
This study compares treatment of Neonatal Abstinence Syndrome (NAS) with two different drugs for the difference in the length of treatment.
- Trial name
- HOMENOW (NCT01723722)
- Testing
- Methadone, Diluted Deodorized Tincture of Opium
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Eastern Maine Medical Center
Human Papillomavirus Infection
Comparative Effectiveness of System Interventions to Increase HPV Vaccine Receipt in FQHCs
UCLA and Northeast Valley Health Center (NEVHC), a large, multi-site Federally Qualified Health Center (FQHC), are partnering to address underutilization of the prophylactic HPV vaccine among underserved, ethnic minority…
- Trial name
- NCT03726151
- Testing
- Parent Reminders, Multicomponent clinic-system strategies, Combined Condition
- Where
- 7 sites in United States
- Volunteers
- 17,000 people
- Sponsor
- University of California, Los Angeles
Child Behavior Disorders
Efficacy of Teacher-delivered Child Mental Healthcare in Primary Schools of India
Twenty percent of all children struggle with mental health challenges, most of whom will remain unrecognized, unsupported, and unable to access quality care.
- Trial name
- TeaLeaF (NCT04723277)
- Testing
- Tealeaf-Mansik Swasta (Tealeaf), Enhanced Usual Care (EUC)
- Where
- India
- Volunteers
- 550 people
- Sponsor
- University of North Carolina, Chapel Hill
Morbid Obesity
Efficacy and Mechanism Study of Bariatric Surgery to Treat Moderate to Severe Obesity in Han Chinese Population
This is a long-term follow-up and interventional study in individuals who have been diagnosed with moderate to severe obesity with or without diabetes.
- Trial name
- NCT02653430
- Testing
- Sleeve gastrectomy
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Personality Disorders
Biological Effects of Schema Therapy
Background: The major aim of this study is to compare the effects of emotion focused (experiential) and cognitive interventions of schema therapy (ST) on emotion regulation deficits in patients with borderline personality…
- Trial name
- BE-ST (NCT06367907)
- Testing
- schema therapy
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Jena University Hospital
Acne
Safety & Effectiveness of the BEAM Device in Mild-to-moderate Acne
This study will determine if the use of the BEAM device reduces the signs and symptoms of mild-to-moderate acne.
- Trial name
- NCT01162837
- Testing
- BEAM device
- Where
- 3 sites in United States
- Volunteers
- 33 people
- Sponsor
- Oregon Aesthetic Technologies
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