Clinical trials: Egg Hypersensitivity
Egg Hypersensitivity
Egg Oral Immunotherapy
For patients with Immunoglobulin E (IgE)-mediated food allergy, the current management includes identification of the causative food and avoidance.
- Trial name
- NCT01489553
- Volunteers
- 9 people
- Sponsor
- Children's Hospital of Philadelphia
Food Allergy in Children, Milk Allergy
Comparison Between a Rush and a Conventional Oral Immunotherapy Protocol to Treat Cow's Milk and Hen´s Egg Allergy. CompITO Study
This study investigates the efficacy and safety of two different OIT schemes to treat milk and egg allergic children
- Conditions
- Food Allergy in Children, Milk Allergy, Egg Allergy
- Trial name
- compITO (NCT06976775)
- Testing
- "Rush" regimen, "Conventional" regimen
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Pablo Rodríguez del Rio
Food Allergy in Infants
Early Allergen System Experience
Multiple clinical trials have demonstrated that early allergen introduction, feeding babies common food allergens before six months, decreases children's risk of developing a food allergy.
- Trial name
- EASE (NCT06262867)
- Testing
- Ready. Set. Food! Stage 1 Mix ins
- Where
- United States
- Volunteers
- 1,110 people, healthy volunteers welcome
- Sponsor
- Prollergy dba Ready Set Food
Food Allergy
Baked Egg or Egg Oral Immunotherapy for Children With Egg Allergy
The purpose of this study is to compare Baked Egg vs. Egg Oral Immunotherapy for inducing sustained unresponsiveness to egg exposure in children.
- Trial name
- CoFAR7 (NCT01846208)
- Testing
- Egg Oral Immunotherapy, Baked Egg
- Where
- 5 sites in United States
- Volunteers
- 92 people
- Sponsor
- Hugh A Sampson, MD
Food Allergy, Food Allergy in Infants
Basophil Activation Test to Diagnose Food Allergy
The BAT II Study is a cross-sectional diagnostic study in which children with suspected IgE-mediated allergy to foods (namely cow's milk, egg, sesame and cashew), as defined by a history of an immediate-type allergic reaction to…
- Conditions
- Food Allergy, Food Allergy in Infants, Food Allergy in Children, Food Allergen Sensitisation
- Trial name
- BAT2 (NCT03309488)
- Testing
- Oral food challenge
- Where
- United Kingdom
- Volunteers
- 600 people
- Sponsor
- King's College London
- Egg Hypersensitivity
Time-limited Specific Oral Tolerance Induction in Children With Severe Egg Allergy
To evaluate the efficacy of a 6-month specific oral tolerance induction (SOTI) protocol in inducing tolerance (maximal dose of raw egg emulsion tolerated) in children with severe IgE-mediated egg allergy and a history of at least…
- Trial name
- EGGSOTI (NCT01379651)
- Testing
- Specific oral tolerance induction
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Ospedale Buon Consiglio Fatebenefratelli
Egg Allergy, Eligible for Vaccination Against Influenza
FluMist in Egg Allergic Patients
With the growing public health concerns of seasonal influenza and H1N1 in the United States, the primary means by which this can be addressed is with prevention, namely, vaccination against the influenza virus.
- Trial name
- FluEMIST (NCT01248208)
- Testing
- FluMist intranasal influenza vaccine, Intramuscular influenza injection ("flu shot")
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Walter Reed Army Medical Center
Peanut Allergy, Milk Allergy, Cow's
Investigating Modified Protocols of Oral Immunotherapy to Validate Efficacy and Safety
Protocols for Oral Immunotherapy (OIT) for the main food allergens have been recently incorporated in clinical practice for food allergies and their clinical benefits have been acknowledged in European and Canadian official…
- Conditions
- Peanut Allergy, Milk Allergy, Cow's, Egg Allergy
- Trial name
- IMPROVES (NCT06256146)
- Testing
- Food allergy desensitization / Oral Immunotherapy
- Where
- Canada
- Volunteers
- 360 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Cow Milk Protein Allergy, Hen Egg Allergy
Tolerance to Baked Goods in Allergic Children
Food allergies are more common in children, especially in Western countries. Around 5 to 8% of children have at least one food allergy, compared to only 1-2% of adults.
- Trial name
- BFT (NCT06998225)
- Testing
- Dietary intervention using cookies containing milk or egg low dose., Dietary intervention with cow's milk or egg baked cookies high dose
- Where
- Spain
- Volunteers
- 148 people
- Sponsor
- Fundació Sant Joan de Déu
Hen Egg Allergy
Oral Immunotherapy for Desensitization in Children, Adolescents, and Young Adults With Hen Egg Allergy
To determine the efficacy and safety of AR201 in a characterized oral desensitization immunotherapy (CODIT™) regimen in hen egg-allergic subjects aged 4 to 26 years, inclusive.
- Trial name
- NCT04056299
- Testing
- AR201 powder
- Where
- 11 sites in United States
- Volunteers
- 15 people
- Sponsor
- Aimmune Therapeutics, Inc.
Hypersensitivity, Immediate Hypersensitivity
Oral Immunotherapy for Childhood Egg Allergy
The purpose of this study is to determine if oral immunotherapy (OIT) will desensitize a child with an allergy to egg and eventually lead to the development of tolerance to egg.
- Conditions
- Hypersensitivity, Immediate Hypersensitivity, Food Hypersensitivity
- Trial name
- NCT00461097
- Testing
- Egg oral immunotherapy, Control Group
- Where
- 5 sites in United States
- Volunteers
- 55 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Egg Allergy, Egg Hypersensitivity
Oral Immunotherapy for Children With Egg Allergy
This clinical trial aims to investigate if oral immunotherapy can help children with egg allergy tolerate eggs. Children aged 6-18 months can take part in the trial.
- Conditions
- Egg Allergy, Egg Hypersensitivity, Food Allergy in Children, Food Allergies
- Trial name
- NCT07888439
- Testing
- Oral immunotherapy with egg
- Where
- 5 sites in Denmark
- Volunteers
- 76 people
- Sponsor
- Laura Ozer Kettner
Allergy
Follow up of Patients After Oral Immunotherapy for Cow's Milk, Eggs and Peanuts
Food allergy is a potentially life threatening condition. The current practice consists of elimination diet and injectable epinephrine in case of a reaction.
- Trial name
- OIT followup (NCT01999387)
- Testing
- Allergenic food
- Where
- Israel
- Volunteers
- 500 people
- Sponsor
- Assaf-Harofeh Medical Center
Food Allergy in Infants
Oral Immunotherapy With Egg in Infants
In children allergic to egg, oral immunotherapy (OIT) with egg may accelerate that the children grow out of the food allergy. Children than have a positive oral food provocation with egg with a low threshold, will be offered to…
- Trial name
- OIT egg (NCT07540091)
- Testing
- low-dose OIT egg
- Volunteers
- 40 people
- Sponsor
- Josefine Gradman
Food Allergy, Egg Protein Allergy
Immune Responses in Hen's Egg Oral Immunotherapy
The study determines how a 6 months oral immunotherapy (OIT) program with hen's egg (HE) effects cellular and humoral immune responses in 50 children with HE allergy.
- Conditions
- Food Allergy, Egg Protein Allergy, Immune Tolerance
- Trial name
- NCT03744325
- Testing
- Hen's egg OIT
- Volunteers
- 50 people
- Sponsor
- Helsinki University Central Hospital
Food Allergy in Children
Tolerance Results and Immune Mechanisms in Cow´s Milk and/or Hen´s Egg Allergic Children Following Natural Evolution or Oral Immunotherapy
Allergy to Cow's milk and hen´s egg proteins are the most common causes of food allergies in early childhood and are associated with the occurrence of adverse events that may be life-threatening, quality of life impairment and…
- Trial name
- alerITO (NCT07419243)
- Testing
- Oral Immunotherapy, Allergenic food avoidance
- Where
- Spain
- Volunteers
- 68 people
- Sponsor
- Fundación de Investigación Biomédica - Hospital Universitario de La Princesa
Egg Allergy
Clinical Tolerance to a Live Attenuated Vaccine Against Influenza (Flumist®) in a Population Allergic to Eggs
The objective of this study is to verify the clinical tolerance to the vaccine Flumist (intranasal live attenuated influenza vaccine) in a population of egg allergic children.
- Trial name
- NCT02142491
- Where
- Canada
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Food Allergy
Open-label Extension Study of ADP101
This is an open-label, safety extension study for participants who participated in the Harmony study (protocol ADP101-MA-01).
- Trial name
- NCT05243719
- Testing
- ADP101
- Where
- 14 sites in United States
- Volunteers
- 45 people
- Sponsor
- Alladapt Immunotherapeutics, Inc.
Egg Allergy
Pancake Oral Immunotherapy For Egg Allergy In Inducing Tolerance
Oral immunotherapy (OIT) using raw/ cooked egg has good desensitisation outcomes but is associated with frequent and sometimes severe adverse events (anaphylaxis is not uncommon).
- Trial name
- POET (NCT07192510)
- Testing
- Pancake oral immunotherapy
- Where
- Singapore
- Volunteers
- 23 people
- Sponsor
- KK Women's and Children's Hospital
Egg Hypersensitivity
Safety of Nasal Influenza Immunisation in Egg Allergic Children
Egg allergy is common in early childhood, affecting at least one in 50 preschool children. Influenza ("'flu") vaccines contain egg protein, as the vaccine is cultured in hen's eggs.
- Trial name
- SNIFFLE (NCT01859039)
- Testing
- Administration of Live attenuated influenza vaccine
- Where
- 12 sites in United Kingdom
- Volunteers
- 282 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust