Clinical trials: Elastography
Spleen; Fibrosis
Optimization of Spleen VCTE Examinations with FibroScan
This is an European, prospective, interventional, and multicenter clinical investigation which main objective is to develop a spleen examination dedicated to overweight or obese patients and assess its applicability.
- Trial name
- NCT05122416
- Testing
- FibroScan examination (S), FibroScan examination (M), FibroScan examination (XL)
- Where
- 4 sites in Netherlands, Romania and 1 more
- Volunteers
- 433 people
- Sponsor
- Echosens
NAFLD
Use of Shear Wave Elastography to Assess Non-alcoholic Fatty Liver Disease (NAFLD)
The aim of this study is to test a non-invasive imaging technique to reliably diagnose NAFLD in children and adolescents with obesity and assess the degree of fibrosis.
- Trial name
- NAFLD (NCT03587298)
- Testing
- Real-Time (Supersonic)- 2D shear wave elastography (rt-SWE)
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Biliary Atresia, Alagille Syndrome
FibroScan™ in Pediatric Cholestatic Liver Disease (FORCE)
Noninvasive monitoring of liver fibrosis is an unmet need within the clinical management of pediatric chronic liver disease. While liver biopsy is often used in the initial diagnostic evaluation, subsequent biopsies are rarely…
- Conditions
- Biliary Atresia, Alagille Syndrome, Alpha1 Anti-Trypsin Deficiency, Portal Hypertension
- Trial name
- FORCE (NCT02922751)
- Testing
- Liver Stiffness Measurement (LSM)
- Where
- 13 sites in United States, Canada
- Volunteers
- 552 people
- Sponsor
- Arbor Research Collaborative for Health
Epididymo-orchitis
Elastography in Boys With Epididymo-orchitis
The patients treated in our clinic for epididymoorchitis will be given scrotal shear wave elastography by the Department of Radiology and affected testis will be compared to non affected testis radiologically.
- Trial name
- NCT03969979
- Testing
- Shear wave elastography
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Trakya University
Cerebral Palsy
Can Gait Analysis and Ultrasound Detect a Change in Calf Musculature in Children With Cerebral Palsy?
ORLAU is a clinical department of the Robert Jones and Agnes Hunt Orthopaedic Hospital. We treat patients with a wide range of movement disorders affecting their walking or arm function.
- Trial name
- NCT04290689
- Testing
- Botulinum Toxin-A injection, Serial casting stretching
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Obesity & Overweight, Pediatric Obesity
Ultrasound Assessment of Tongue Characteristics in Children and Adolescents With Obesity
This longitudinal observational study aims to validate ultrasound-based tongue markers related to tongue characteristics, including fat accumulation, morphologic and mechanical properties of the tongue in children and adolescents…
- Conditions
- Obesity & Overweight, Pediatric Obesity, Obstructive Sleep Apnea (OSA)
- Trial name
- NCT07370350
- Testing
- Submental ultrasound
- Where
- 2 sites in Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Haute Ecole Bruxelles-Brabant
Juvenile Hallux Valgus, Ultrasound
Investigation of the Effects of Exercise in Individuals With Juvenile Hallux Valgus
This study aims to evaluate the short- and long-term effects of toe spread-out exercises, performed under supervision for 3 months, on the angular severity of deformity and the electromechanical activity, stiffness, and thickness…
- Conditions
- Juvenile Hallux Valgus, Ultrasound, Shear Wave Elastography
- Trial name
- NCT07827846
- Testing
- Toe Spread Out Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 4 people
- Sponsor
- Ankara Yildirim Beyazıt University
Cirrhosis
Assessment of Liver Fibrosis and Prognosis in Chinese Patients With CHB Infection Using STE/STQ Elastography
This national multicenter prospective study is aimed to study the diagnositic performance of STE/STQ elastography in liver fibrosis and prognosis in patients with chronic hepatitis B infection.
- Trial name
- NCT03530657
- Volunteers
- 460 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Chronic Hepatitis
Accuracy of RTE for Evaluating Hepatic Fibrosis in Chronic Hepatitis: a Prospective Multicenter Study
Our study is a prospective multicenter research and the aim is to explore a variety of suitable evaluation indicators and criteria for diagnosis of diffuse liver fibrosis, to get the corresponding diagnosis threshold, with the…
- Trial name
- NCT02143180
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Single Ventricle Heart Disease
Evaluation of Fontan-associated Hepatic Stiffness and the Efficacy of Udenafil in Reducing Liver Stiffness
A study to evaluate the efficacy of MZ101 therapy in reducing liver stiffness.
- Trial name
- FALD (NCT03430583)
- Testing
- Udenafil
- Where
- 17 sites in United States, Canada
- Volunteers
- 88 people
- Sponsor
- Mezzion Pharma Co. Ltd
Endometriosis, Adenomyosis
Diagnosis of Adenomyosis Using Ultrasound, Elastography and MRI
comparison of transvaginal ultrasound, transvaginal ultrasound elastography and MRI for the diagnosis of adenomyosis in patients receiving hysterectomy afterwards
- Trial name
- NCT04665414
- Testing
- MRI, transvaginal ultrasound, transvaginal ultrasound elastography
- Where
- Germany
- Volunteers
- 103 people
- Sponsor
- University Hospital Muenster
Elastography, Fibrosis, Liver
The Use of the Transient Elastography Paediatric Probe, Compared to the M Probe, Indirect Biomarkers and Histology
The purpose of this study is to assess the reliability, reproducibility and accuracy of the paediatric probe of transient elastography in detecting liver fibrosis in children, besides its limitations and side effects.
- Conditions
- Elastography, Fibrosis, Liver, Pediatrics, Chronic Liver Disease
- Trial name
- NCT04380493
- Testing
- hepatic transient elastography using S probe and M probe
- Where
- Spain
- Volunteers
- 141 people
- Sponsor
- Hospital Vall d'Hebron
Urea Cycle Disorder, Ornithine Transcarbamylase Deficiency
Liver Disease in Urea Cycle Disorders
This is a multi-center, cross-sectional study to assess risk for liver fibrosis and hepatic injury in individuals with urea cycle disorders (UCDs) using serum biomarkers, Fibroscan, and MRE.
- Conditions
- Urea Cycle Disorder, Ornithine Transcarbamylase Deficiency, Citrullinemia 1, ARGI Deficiency
- Trial name
- NCT04612764
- Where
- 5 sites in United States
- Volunteers
- 62 people
- Sponsor
- Baylor College of Medicine
Fontan Operation
Stage 3 Fontan Operation Liver Ultrasound Study
The purpose of this study is to compare the liver stiffness, which can be caused by congestion and fibrosis in pediatric patients before and after a Fontan heart operation.
- Trial name
- NCT02269709
- Testing
- ARFI Ultrasound
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Michigan
Chronic Liver Disease
Elastography in Chronic Liver Disease in Children
Chronic liver disease is a significant health issue among children and it can result in fibrosis, cirrhosis and liver failure. Since the prognosis and monitoring of these diseases are different from each other,, Conventional…
- Trial name
- NCT04774601
- Volunteers
- 50 people
- Sponsor
- Assiut University
Liver Diseases
Role of Combined Ultrasound Elastography in Evaluation the Degree of Liver Fibrosis in Children With Cholesteric Liver Disease
Pediatric CLDs are diverse, encompassing a broad spectrum of conditions, from congenital and metabolic disorders to autoimmune and viral diseases.
- Trial name
- NCT06724731
- Volunteers
- 45 people
- Sponsor
- Assiut University
Rheumatoid Arthritis
SonoElastography of Median Nerve in Rheumatoid Arthritis
To assess the role of ultrasonography and SE in detecting the median nerve changes before progression to CTS in patients with RA.
- Trial name
- NCT06135129
- Testing
- Sonoelastography
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Assiut University
Superficial Lymphadenopathy
Elastography in Superficial Lymphadenopathy
Evaluation of the role of Ultrasound Elastography in differentiation between benign and malignant lymph nodes and its additional information over the classic gray scale and color Doppler ultrasound.
- Trial name
- NCT04561999
- Testing
- Elastography
- Volunteers
- 70 people
- Sponsor
- Assiut University
Keloid
Multimodal Ultrasound Imaging Assessment on Keloid
Skin keloids are common dermatological conditions that can lead to physical limitations, functional impairments, and deformities.
- Trial name
- NCT06034587
- Testing
- multimodal ultrasound, radioisotope applicator therapy
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Chongqing Medical University
Prematurity
Preterm Neonates Brain Ultrasound With CEUS and Elastography
The aim of the study is to investigate levels of brain perfusion and elasticity in preterm neonates when they reach the estimated due date and to compare the data with magnetic resonance imaging at term.
- Trial name
- NCT05694611
- Testing
- Brain contrast enhanced ultrasound, brain ultrasound elastography, Sulfur Hexafluoride
- Where
- Finland
- Sponsor
- Turku University Hospital