Clinical trials: Elective Surgeries
Myocardial Repolarization, Healthy
The Effects of Dexmedetomidine on the Heart Beat During Elective Surgery in Children
Dexmedetomidine is a sedative drug that is commonly used to improve calmness and reduce pain in children waking up after surgery.
- Trial name
- DexmedQT (NCT02353169)
- Testing
- Dexmedetomidine, Saline
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- University of British Columbia
Anesthesia, Anxiety
Media Use, Anxiety, Sedation, and Recovery in Children Having Upper GI Endoscopy
This observational study will investigate whether problematic digital media use is associated with anxiety in children undergoing a planned upper gastrointestinal endoscopy, a camera examination of the upper digestive tract.
- Trial name
- PMU-ASR-ENDO (NCT07916168)
- Testing
- Problematic Media Use
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Caesarean
Prophylactic Ceftizoxime (Cefizox) for Elective Cesarean Delivery
Ceftizoxime (Cefizox) will reduce post Cesarean delivery febrile morbidity.
- Trial name
- NCT01347593
- Testing
- ceftizoxime
- Where
- Sudan
- Volunteers
- 220 people
- Sponsor
- University of Khartoum
Elective Bilateral Myringotomy
Sublingual Ketorolac Compared to Intranasal Dexmedetomidine for Postoperative Analgesia in Pediatric Patients Undergoing Bilateral Myringotomy
The investigators aim to compare intranasal dexmedetomidine in a dose of 1ug.kg-1 with sublingual ketorolac in a dose of 1mg.kg-1 on postoperative behaviour in those children undergoing BMT during their PACU stay
- Trial name
- NCT03742180
- Testing
- intranasal dexmedetomidine, sublingual ketorolac
- Where
- Egypt
- Sponsor
- Mansoura University
Preoperative Period, Nutritional Status
Preoperative Nutritional Status in Patients Undergoing Elective Total Knee Arthroplasty and In-hospital Postoperative Complications
Malnutrition has long been linked to postoperative complications and adverse outcomes in a variety of surgical fields , such as increased susceptibility to infection, delayed wound healing, and increased frequency of decubitus…
- Conditions
- Preoperative Period, Nutritional Status, Arthroplasty Knee
- Trial name
- NUTR TKA (NCT03549962)
- Testing
- TKA
- Where
- 2 sites in Hong Kong
- Volunteers
- 626 people
- Sponsor
- Chinese University of Hong Kong
Patients Undergoing Elective Surgery With Anesthesia
Telemedical Risk Assessment and Preoperative Evaluation (TAPE)
The purpose of this study is to assess the feasibility, patient satisfaction and time saving of a telemedical risk assessment and preoperative evaluation for anesthesia.
- Trial name
- NCT04518514
- Testing
- TAPE-Software
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- RWTH Aachen University
Colostomy, Hirschsprung Disease - Pull Through
Bowel Preparation in Elective Pediatric Colorectal Surgery
Infections after elective intestinal surgery remain a significant burden for patients and for the health care system. The cost of treating a single surgical site infection is estimated at approximately $27,000.
- Conditions
- Colostomy, Hirschsprung Disease - Pull Through, Necrotizing Enterocolitis, Inflammatory Bowel Diseases
- Trial name
- NCT03593252
- Testing
- Senna, Sodium Picosulfate, Magnesium Oxide and Citric Acid, Metronidazole Oral
- Volunteers
- 81 people
- Sponsor
- McMaster University
Intestinal Diseases, Intestinal Resection
Implementation of a Pediatric ERAS-based Protocol in Intestinal Resection With Primary Anastomosis
Enhanced Recovery After Surgery (ERAS) is a multimodal perioperative care strategy designed to reduce surgical stress, decrease postoperative complications, and accelerate recovery after surgery.
- Trial name
- PeERAS (NCT07504549)
- Testing
- Standardized Pediatric ERAS-Based Perioperative Protocol
- Where
- 9 sites in Poland
- Volunteers
- 120 people
- Sponsor
- Michał Pasierbek
Abortion, Therapeutic
A Randomized Study of Cervical Priming With Misoprostol Prior to Elective First Trimester Pregnancy Termination
The purpose of this study is to determine whether misoprostol administered prior to elective first trimester pregnancy has an effect on pain and ease of procedure and complications.
- Trial name
- NCT00310921
- Testing
- Misoprostol
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Peritoneal Contamination After Ileocolonic Anastomosis, Wound Infection
Microbiological Spectrum of the Intraperitoneal Surface After Elective Right-sided Colon Cancer
Despite performing colonic surgery with strict asepsia measures, minimizing the contact of the colon lumen with the peritoneum, some contamination is nearly impossible to avoid.
- Conditions
- Peritoneal Contamination After Ileocolonic Anastomosis, Wound Infection, Intra-abdominal Abscess
- Trial name
- NCT01458353
- Testing
- Stapled anastomosis, Handsewn anastomosis
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Hospital General Universitario Elche
Analgesia
Pharmacokinetic Study of Intranasal CT001 in Children 1-17 Years of Age Undergoing Elective Surgical Procedures
This is a prospective non-randomized, open-label, single dose (and a second dose if needed), PK study in 25 children age 1-17 years.
- Trial name
- NCT04897750
- Testing
- CT001
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Cessatech A/S
Blood Loss, Hemoglobin Change
Prospective Investigation of Intra-Articular Tranexamic Acid Use in Elective Hip Arthroplasty
Tranexamic acid (trans-4-aminomethyl cyclohexane carboxylic acid) is an antifibrinolytic substance that chemically belongs to the group of e-carboxylic acids.
- Conditions
- Blood Loss, Hemoglobin Change, Blood Transfusion, Heterotopic Ossification
- Trial name
- NCT06903299
- Testing
- Intra-articular Tranexamic acid application
- Where
- Czechia
- Volunteers
- 1,000 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Hemophilia A
Study Evaluating B-Domain Deleted Recombinant Factor VIII (BDDrFVIII, ReFacto AF) in Patients With Hemophilia A Undergoing Elective Major Surgery
This study will examine the efficacy and safety of ReFacto AF in patients with severe and moderately severe hemophilia A undergoing elective major surgery when administered by either bolus injections (BI) or continuous infusion…
- Trial name
- NCT00243659
- Testing
- ReFacto AF
- Where
- 17 sites in United States, Australia and 6 more
- Volunteers
- 30 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Obesity, Pregnancy
A Trial of the Use of Ultrasound to Aid the Insertion of Combined Spinal Epidural Anaesthesia
The study will establish whether the use of ultrasound scanning with a purpose built probe will aid the insertion of the needles for epidural and spinal anaesthesia for obese women undergoing elective caesarean section The study…
- Trial name
- NCT00166699
- Testing
- ultrasound
- Where
- 5 sites in United Kingdom
- Volunteers
- 42 people
- Sponsor
- NHS Greater Glasgow and Clyde
Inguinal Hernia, Quality of Life
Objective and Perceived Quality Study in Patients Undergoing Elective Groin Hernia Surgery
This is a prospective non-comparative observational study of cohorts. Consists on offering surveys to every patient undergoing groin hernia surgery in our Abdominal Wall Surgery Unit, in Hospital of Navarra.
- Conditions
- Inguinal Hernia, Quality of Life, Surgery, Survey
- Trial name
- NCT03860285
- Testing
- Short form 36 quality of life survey
- Where
- Spain
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- Hospital of Navarra
Blood Transfusion
Perioperative Transfusion Related Outcome
A secondary analysis of the Turkish National Perioperative Transfusion Study (TULIP TS) database will be performed.
- Trial name
- NCT03930355
- Testing
- Blood transfusion, Control
- Where
- 60 sites in Turkey (Türkiye)
- Volunteers
- 6,121 people
- Sponsor
- Diskapi Teaching and Research Hospital
Pediatric Sedation, Clonidine Sedation
Premedication in Children: a Clinical Trial Comparing Oral Ketamine and Oral Clonidine With Respect to Sedation Level and Opioid Consumption in Pediatrics Undergoing Elective Lower Abdominal Day-case Surgery.
Aim of the work Is to compare between oral ketamine and oral clonidine regarding the level of sedation pre and postoperatively in addition the need of opioids administration intraoperative in children undergoing elective lower…
- Conditions
- Pediatric Sedation, Clonidine Sedation, Ketamine Sedation
- Trial name
- NCT07461376
- Testing
- Oral Clonidine (OC)
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Cairo University
Insulin Resistance
Carbohydrate Loading in Lowering Perioperative Insulin Resistance in Pediatric Surgery
It is a double blinded randomized controlled trial interventional study, examining the effect of carb loading given prior to surgery on preventing post operative insulin resistance in pediatric patients undergoing elective surgery
- Trial name
- NCT07545538
- Testing
- Carbohydrate loading
- Where
- Indonesia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Gadjah Mada University
Von Willebrand Disease
A Study of Recombinant Von Willebrand Factor (rVWF) With or Without ADVATE in Children With Severe Von Willebrand Disease (VWD)
The main aim of the study is to check effectiveness, side effects, and tolerability of vonicog alfa (recombinant von Willebrand factor [rVWF]), with or without ADVATE, in the treatment and control of nonsurgical bleeding events…
- Trial name
- NCT02932618
- Testing
- Vonicog alfa, Antihemophilic Factor (Recombinant)
- Where
- 46 sites in United States, Austria and 11 more
- Volunteers
- 47 people
- Sponsor
- Baxalta now part of Shire
Idiopathic Scoliosis
Evaluation of Analgesia for Spine Fusion Elective Surgery in Children
The multicenter PRECISE Analgesia (Prospective Randomized Evaluation of Analgesia for Idiopathic Scoliosis Spine Fusion Elective Surgery in Children) trials will a) implement and investigate the efficacy and safety of multidose…
- Trial name
- PRECISE (NCT06626503)
- Testing
- Methadone based ERAS, Non-methadone based group
- Where
- 4 sites in United States
- Volunteers
- 500 people
- Sponsor
- Senthil Sadhasivam