Clinical trials: Embryo Development
Autism Spectrum Disorder, Complication of Prematurity
Correlation of CXCR4 Expression in Premature Infants With a Diagnosis of Autism at 24 Months
Preterm children are at increased risk for autism spectrum disorders, with an estimated rate of 10%. In the US, about 1 in 8 pregnancies ends with a premature birth.
- Trial name
- ASD-CXCR4 (NCT01686685)
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Embryonic Development, Retinal Anomalies
Mapping of the Developmental Atlas of the Visual System and Research on Embryonic Neurogenesis Phenomena
This research studies how nerve cells in the human embryonic retina, visual brain regions, and brain areas responsible for higher cognitive functions grow, develop, and form interconnected functional networks.
- Conditions
- Embryonic Development, Retinal Anomalies, Neural Development
- Trial name
- NCT07688538
- Testing
- Tissue collection and multi-omics sequencing analysis
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sheng Liu
Embryo Development
Impact of Culture Medium on Embryo Quality
The purpose of this study is to compare two culture media.
- Trial name
- NCT01094314
- Testing
- embryo culture medium
- Where
- Belgium
- Volunteers
- 790 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Sperm DNA Fragmentation, Male Fertility
Impact of Telomere Biology and Sperm DNA Fragmentation on Embryonic Development
The proposed project we intend to assess the implication of the telomeric pathway in male infertility. To get this, several analyzes will be carried out: 1. Determination of the TL by means of two methods: Q-FISH and PCR. 2.
- Conditions
- Sperm DNA Fragmentation, Male Fertility, Telomeres, Sperm
- Trial name
- NCT05508217
- Where
- Spain
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- IVI Madrid
Child Development, Endometrial Preparation
Development of IVF/ICSI Children Born From Different Endometrial Preparation Protocols
The efficacy and safety of endometrial preparation regimens remain controversial. In the most recent meta-analysis, using natural and modified natural cycle protocol to prepare the endometrium in frozen embryo transfer resulted…
- Trial name
- MONARTBABIES (NCT05502770)
- Testing
- Developmental score according to The Ages & Stages Questionnaires®, Third Edition - ASQ®-3, Physical development and General Health, Developmental Red flags
- Where
- Vietnam
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Mỹ Đức Hospital
Preimplantation Genetic Testing (PGT), Frozen Embryo Transfer Cycle
Effects of Trophectoderm (TE) Biopsy on the Health and Development of Children Born After Preimplantation Genetic Testing (PGT) Cycles.
This study aims to investigate the effects of trophectoderm (TE) biopsy on the health and development of children born after preimplantation genetic testing (PGT) cycles.
- Conditions
- Preimplantation Genetic Testing (PGT), Frozen Embryo Transfer Cycle, Assisted Reproduction Technologies, Postnatal Health
- Trial name
- NCT07349966
- Testing
- Questionnaire
- Where
- Italy
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Polycystic Ovary Syndrome, IVF
Follicular Fluid Raman Shifts and IVF Outcomes
This study intends to collect about 150 cases of follicular fluid samples from PCOS and non-PCOS infertility patients undergoing in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) cycles (in clinical…
- Trial name
- NCT04838535
- Testing
- Raman spectrum
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Normal Healthy Embryos
Derivation of New Human Embryonic Stem Cell Lines: Identification of Instructive Factors for Germ Cells Development
The purpose of this study is 1. To generate human embryonic stem cells lines (hESC) lines 2. Study of the factors that contribute to differentiation towards germ cell.
- Trial name
- NCT01165918
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Embryo Development
Culture Media and Blastocyst Development
The aim of this non-interventional study is to compare the blastulation rate per fertilized oocyte in two different single step culture media commercially available (GEMS and Irvine culture media).
- Trial name
- NCT03497052
- Testing
- In vitro culture in medium 1, In vitro culture in medium 2
- Where
- Italy
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Clinica Valle Giulia
Embryo Development
Impact of Culture Conditions on the Embryo Quality
The purpose of this study is to compare different culture conditions. The effect of the type of incubator (standard versus mini-incubator) and the effect of the oxygen concentration (5% versus 20%) will be evaluated on the embryo…
- Trial name
- NCT01767805
- Testing
- Standard incubator, Mini incubator, 5% oxygen
- Where
- 2 sites in Belgium
- Volunteers
- 790 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg