Clinical trials: Emphysema, open to volunteers
Interstitial Lung Disease, COPD
Global Utilization And Registry Database for Improved preservAtion of doNor LUNGs
The objective of this registry is to collect and evaluate various clinical effectiveness parameters in patients with transplanted donor lung that were preserved and transported within the LUNGguard system, as well as…
- Conditions
- Interstitial Lung Disease, COPD, Cystic Fibrosis, Pulmonary Fibrosis
- Trial name
- GUARDIANLUNG (NCT04930289)
- Testing
- LungGuard, BAROGuard
- Where
- 15 sites in United States, Belgium
- Volunteers
- 3,500 people
- Sponsor
- Paragonix Technologies
Emphysema
Analysing Peripheral Skeletal Muscle Function Before and After Endobronchial Valve Treatment
Rationale: Chronic obstructive pulmonary disease (COPD) is characterised by a high prevalence of peripheral muscle dysfunction, which can have significant clinical consequences, including decreased exercise capacity, reduced…
- Trial name
- ENDURANCE (NCT06025500)
- Testing
- 31P-Magnetic Resonance Spectroscopy (31P-MRS)
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- University Medical Center Groningen
COPD
Change in Task-related Oxygen Uptake After EBV Treatment
Rationale: Bronchoscopic lung volume reduction using endobronchial valves (EBV) has emerged as a viable treatment option for eligible patients with severe emphysema.
- Trial name
- CROCODILE (NCT06702072)
- Testing
- Endobronchial valve treatment
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- University Medical Center Groningen
COPD
Bronchoscopic EmphysemA Treatment in THE NetherLands
Rationale: New bronchoscopic treatments for emphysema have shown promise in clinical trials, improving lung function, exercise capacity and possibly survival and are now being adopted by a number of centres in the Netherlands.
- Trial name
- BREATHE-NL (NCT02815683)
- Where
- 2 sites in Netherlands
- Volunteers
- 500 people
- Sponsor
- University Medical Center Groningen
Emphysema or COPD
Biological Investigation of Explanted Endobronchial Lung Valves Study
Rationale: COPD is a severe, often progressive and currently incurable lung disease which affects both the upper airways (chronic bronchitis) as well as the lower airways (emphysema).
- Trial name
- Bio-EXCEL (NCT04214587)
- Testing
- tissue and blood sampling
- Where
- Netherlands
- Volunteers
- 150 people
- Sponsor
- University Medical Center Groningen