Clinical trials: End Tidal CO2
End Tidal CO2, CO2 Removal
A New and Innovative Method for CO2 Removal in Anesthetic Circuits: Replacing Chemical Granulate
CO2 removal is a mandatory part of modern anesthesia systems. Current chemical absorbers pose problems as the chemical granulate reacts not only with the CO2 but also the anesthetic drugs, producing organ toxic substances.
- Trial name
- NCT02195245
- Testing
- memsorb
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- DMF Medical Incorporated
out-of Hospital Cardiac Arrest
Pre-Hospital Cerebral Oxygenation and End-Tidal CO2 During Cardiopulmonary Resuscitation (CPR)
Cerebral saturation will be measured pre-hospital during an out-of hospital cardiac arrest with O3TM regional oximetry for Root® (Masimo®).
- Trial name
- CopernicusIb (NCT02850237)
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Hasselt University
Anesthesia, General, Infant
Impact of CO2 on Cerebral Blood Flow in Infants Less Than 6 Months During General Anaesthesia
The study aims at assessing cerebral blood flow variations following expired CO2 variations in anaesthetized infants less than 6 months, during a routine general anesthesia.
- Trial name
- NCT03567031
- Testing
- EtCO2 modification
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Anesthesia, Hypercapnia
End Tidal Carbon Dioxide Concentration and Depth of Anesthesia in Children
Carbon Dioxide (CO2) is a by-product of metabolism and is removed from the body when we breathe out. High levels of CO2 can affect the nervous system and cause us to be sleepy or sedated.
- Conditions
- Anesthesia, Hypercapnia, Hypocapnia
- Trial name
- NCT06303518
- Testing
- High normal ETCO2: ETCO2 50 mmHg (+/- 3mmHg), Normal ETCO2: ETCO2 40 mmHg (+/- 3mmHg), Low Normal ETCO2: ETCO2 30 mmHg (+/- 3mmHg)
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Diabetes Mellitus
EtCO2 for Monitoring and Predicting Severity of DKA in Pediatric Emergency, Doha, Qatar.
Metabolic acidosis is one of the important and life-threatening pathophysiological changes in DKA and its monitoring is essential.
- Trial name
- NCT04121572
- Testing
- Nasal cannula capnography
- Where
- Qatar
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Hyperventilation Syndrome, Hypocapnia
Comparison of Transcutaneous Vs End-tidal CO2 Pressure Measurements in Hyperventilation Syndrome Diagnosis
Hyper Ventilation Syndrome is a frequent disease affecting adults whose diagnosis is often belated or even unrecognized due to the lack of "gold standard" criteria.
- Conditions
- Hyperventilation Syndrome, Hypocapnia, Alkalosis, Respiratory, Hyperventilation
- Trial name
- TCvsPETCO2 (NCT03614806)
- Testing
- Simultaneous Transcutaneous and End-tidal CO2 measurements
- Where
- France
- Volunteers
- 14 people
- Sponsor
- University Hospital, Rouen
Complication of Anesthesia
End Tidal Carbon Dioxide in Minimal Sedation
This randomized controlled study investigated the effect of end-tidal carbon dioxide monitoring in pediatric patients undergoing minimal sedation.
- Trial name
- ETCO2 (NCT04868266)
- Testing
- end tidal carbon dioxide monitoring
- Where
- South Korea
- Volunteers
- 214 people
- Sponsor
- Seoul National University Hospital
Metabolic Acidosis, Diabetic Ketoacidosis
Diabetic Ketoacidosis Diagnosis and Management
This is the first and only study conducted on the use of capnography in children diagnosed with DKA to evaluate the initial clinical grading of DKA, monitor clinical improvement, and predict complications such as brain edema.
- Conditions
- Metabolic Acidosis, Diabetic Ketoacidosis, Brain Edema
- Trial name
- NCT06327737
- Testing
- Capnography
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Akdeniz University
Delivery Room Resuscitation
Quantitative End Tidal CO2 Monitoring in the Delivery Room (DR)
This is a trial evaluating the use of an end tidal CO2 monitor during ventilation in the delivery room. The use of the monitor is compared with clinical assessment of ventilation.
- Trial name
- NCT01381068
- Testing
- End tidal CO2 monitor
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Neil Finer
Anesthesia, General
The Effect of End-tidal Carbon Dioxide Level on the Optic Nerve Sheath Diameter in Pediatric Patients
Because the optic nerve is surrounded by the cerebrospinal fluid, increase / decrease in the intracranial pressure can be examined by an increase / decrease in the optic nerve sheath diameter (ONSD).
- Trial name
- NCT03988868
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Seoul National University Hospital
Death, Sudden, Cardiac, Perfusion Index
Is the Perfusion Index an Accurate Predictor of Return of Spontaneus Circulation in Out-of-hospital Cardiac Arrest
The purpose of this pilot feasibility study is to evaluate the ability of the Perfusion Index to predict the return to spontaneous circulation of the out-of-hospital cardiac arrest patient during cardiopulmonary resuscitation.
- Conditions
- Death, Sudden, Cardiac, Perfusion Index, Return of Spontaneous Circulation
- Trial name
- NCT05383885
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Child, Only, Infant, Newborn, Diseases
Capnography Monitoring in Ventilated Children
End-tidal CO2 measurements in children will be assessed for their accuracy with arterial CO2 measurements.
- Conditions
- Child, Only, Infant, Newborn, Diseases, Critical Illness, ARDS, Human
- Trial name
- NCT04354220
- Testing
- capnography monitoring, arterial blood gas
- Where
- Switzerland
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Vincenzo Cannizzaro
Intraoperative Ventilation
Arterial to End-Tidal Carbon Dioxide Difference During Pediatric Laparoscopic Surgeries
Studying the arterial to end-tidal carbon dioxide difference in children undergoing laparoscopic surgeries under different intra-abdominal pressures is of extreme importance.
- Trial name
- PaCO2-EtCO2 (NCT03361657)
- Where
- Egypt
- Volunteers
- 29 people
- Sponsor
- Assiut University
Endoscopy
Is End Tidal CO2 Level Elevation During Upper Endoscopy With CO2 Gas Insufflation Physiologically Significant
During the course of an endoscopic procedure, air has historically been used to inflate the lumen to provide adequate visualization and allow for the endoscope to advance as necessary.
- Trial name
- ETCO2 (NCT04541667)
- Testing
- Air, Carbon Dioxide
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Nebraska
Preterm Birth
Use of CO2 Detectors to Help Provide Effective Breaths During Resuscitation of Preterm Newborns
Effective ventilation is the single most vital intervention to improve outcome of resuscitation in the neonatal population. Assessments of effective ventilations are based on clinical parameters, but may be difficult due to…
- Trial name
- NCT04287907
- Testing
- Monitor Group
- Where
- Singapore
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Verifying the Correct Position of Intravenous Catheters
Intravenous Sodium Bicarbonate Verifies Intravenous Position of Catheters in Children
Sodium bicarbonate injected into a blood vessel transforms to carbon dioxide and water. The increase in carbon dioxide production can be detected by measuring the exhaled carbon dioxide in the lungs.
- Trial name
- NCT01409083
- Testing
- intravenous sodium bicarbonate
- Where
- Israel
- Volunteers
- 18 people
- Sponsor
- Sheba Medical Center
Carbon Dioxide
The Effect of Wearing Masks on End-tidal Carbon Dioxide and Pulse Oximetry
An Interventional Study is planned with the primary purpose of screening for changes in end-tidal carbon dioxide (ETCO2), inspired carbon dioxide (ICO2), and other vital signs that may develop after donning a disposable surgical…
- Trial name
- NCT05114993
- Testing
- wearing a disposable surgical mask
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Patrick Brooks
Pulmonary Ventilation
Comparison of Ventilation Tubes Among Anesthetized Pediatrics
To discover whether different types of ventilation breathing tube influence ventilation effect of children/ neonate, the investigators analysis tidal volume, end tidal carbon dioxide, compliance among children and neonate under…
- Trial name
- NCT03822689
- Testing
- Ventilator breathing tube F2220, Ventilator breathing tube F2216, Ventilator breathing tube F1520
- Where
- Taiwan
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital