Clinical trials: Endocrine Disorders
Type 1 Diabetes Mellitus, Coronary Artery Disease
Vascular Inflammation in Adolescents With Type 1 Diabetes
The purpose of this study is to find out if diabetes damages the blood vessels of adolescents with good diabetes control compared to adolescents with less optimal control.
- Trial name
- NCT00933101
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Children's Mercy Hospital Kansas City
Cardiovascular Diseases, Heart Diseases
Epidemiology of Impaired Coagulant Balance in Diabetes
To determine the nature, extent and molecular mechanisms responsible for impaired fibrinolysis in White, Black, Hispanic and American Indian populations with respect to the presence or absence of diabetes.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Diabetes Mellitus, Blood Coagulation Disorders
- Trial name
- NCT00005481
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Type 1 Diabetes
Microbiome in the Acute Stage of New Onset Paediatric Type 1 Diabetes
The goal of this observational study is to learn more about the microbiome and metabolome of children with type 1 diabetes (T1D). The main questions it aims to answer are: 1.
- Trial name
- NCT06157736
- Where
- Ireland
- Volunteers
- 100 people
- Sponsor
- University College Cork
Obesity, Insulin Resistance
Colchicine to Suppress Inflammation and Improve Insulin Resistance in Adults and Adolescents With Obesity
Background: About 40 percent of adults and 20 percent of adolescents in the U.S. have a body mass index over 30 kg/m2. Being overweight may lead to a state of low-level inflammation. This may cause health problems.
- Conditions
- Obesity, Insulin Resistance, Inflammation
- Trial name
- NCT05017571
- Testing
- Colchicine
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Diabetes Mellitus, Type 1
Assessment of Intranasal Glucagon in Children and Adolescents With Type 1 Diabetes
The purpose of this study was to assess how glucagon administered nasally, using a nasal dosing delivery device, works in children and adolescents compared with commercially-available glucagon given by injection.
- Trial name
- NCT01997411
- Testing
- Nasal Glucagon, Intramuscular Glucagon
- Where
- 7 sites in United States
- Volunteers
- 48 people
- Sponsor
- Eli Lilly and Company
Type 1 Diabetes, Eating Disorder
Develop and Validate a Self-Administered Instrument That Will Screen for Eating Disorder Symptoms in Persons Aged 12 and Older With Type 1 Diabetes.
The purpose of this study is to develop and validate a survey instrument to be used by persons with type 1 diabetes aged 12 and older to screen for an eating disorder.
- Trial name
- NCT00948311
- Where
- United States
- Volunteers
- 279 people
- Sponsor
- HealthPartners Institute
Diabetes, Diabetes Mellitus, Type 2
Non-Interventional Study on Safety of Liraglutide in Subjects With Type 2 Diabetes
This trial is conducted in Asia. The aim of this trial is to investigate the safety profile of liraglutide under normal conditions of use.
- Trial name
- Lead-Ph (NCT01345734)
- Testing
- liraglutide
- Where
- Philippines
- Volunteers
- 1,056 people
- Sponsor
- Novo Nordisk A/S
Pituitary Diseases, Pituitary Neoplasms
Long Term Outcome Study in Patients With Pituitary Disorders
To determine the outcomes of patients with different pituitary disorders whether they are managed medically, surgically or expectantly.
- Trial name
- NCT03665064
- Volunteers
- 1,500 people
- Sponsor
- University of Alberta
Diabetes Mellitus, Type II
Effect of Glucose Control on the Response to Aspirin in Type 2 Diabetic Patients
The efficacy of low dose aspirin appears to be substantially lower in diabetic patients, compared to patients without diabetes. We will perform an observational study where we follow up patients with uncontrolled type 2 Diabetes…
- Trial name
- NCT00649909
- Where
- Israel
- Volunteers
- 18 people
- Sponsor
- Hadassah Medical Organization
Immune Defect, 22q11.2 Deletion Syndrome
Resolution of Primary Immune Defect in 22q11.2 Deletion Syndrome
Evaluate about age of resolution in immune defect in 22q11.2 Deletion Syndrome Incidence of immunodeficiencies in 22q11.2 Deletion Syndrome
- Trial name
- NCT02460328
- Where
- Thailand
- Volunteers
- 43 people
- Sponsor
- Mahidol University
Gynecomastia, Endocrine System Diseases
Skincare Products and Environmental Health
The purpose of this study is to explore the potential for an association between the development of prepubertal gynecomastia and history exposure to lavender essential oil, tea tree essential oil, and other essential oils.
- Trial name
- NCT04836364
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Nutraceuticals Research Institute
Cardio Vascular Disease, Diabetes (DM)
Holistic CRM Care vs Standard of Care in a Primary Care Setting
Cardiovascular disease, high blood pressure, chronic kidney disease, and type 2 diabetes, collectively referred to as Cardio-Renal-Metabolic (CRM) conditions, are among the most common chronic diseases in society.
- Conditions
- Cardio Vascular Disease, Diabetes (DM), Chronic Kidney Disease
- Trial name
- HOPE-CRM (NCT07819383)
- Testing
- CRM care
- Volunteers
- 6,000 people
- Sponsor
- Danderyd Hospital
Diabetes
Lifestyle Intervention in Overweight and Obese Pregnant Hispanic Women
The overall goal of this randomized controlled trial is to test the efficacy of a culturally and linguistically modified, individually tailored lifestyle intervention to reduce excess gestational weight gain (GWG), increase…
- Trial name
- NCT01868230
- Testing
- Lifestyle Intervention
- Where
- United States
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Diabetes, Diabetes Mellitus, Type 1
Evaluation of Levemir® for the Treatment of Type 1 and 2 Diabetes
This study is conducted in Europe. The aim of this observational study is to evaluate the incidence of serious adverse drug reactions while using Levemir® under normal clinical practice conditions.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- PREDICTIVE™ (NCT00655044)
- Testing
- insulin detemir
- Where
- Russia
- Volunteers
- 3,637 people
- Sponsor
- Novo Nordisk A/S
Diabetes, Diabetes Mellitus, Type 1
An Observational Study to Assess Longitudinal Variation of Immune Biomarkers in Subjects at Risk for Development of Type 1 Diabetes
This study is conducted in the United States of America (USA). The aim of the study is to assess longitudinal variation of immune biomarkers in subjects at risk for development of type 1 diabetes (T1D).
- Trial name
- NCT01846312
- Testing
- No treatment given
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus
The Effects of High and Low Blood Glucose Values on the Brain in Children With Type 1 Diabetes Mellitus
Simplified Brochure Neuropsychological Testing/Assessment is like games for the child. They are asked to complete the sequence, identify pictures, explain what is happening, etc. There is no personality testing involved.
- Trial name
- NCT01690481
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Stanford University
Breast Cancer
A Study of HR+/HER2- Metastatic Breast Cancer Patients Treated With Palbociclib Together With an Aromatase Inhibitor From 2017 to 2023 in Denmark.
The purpose of this study is to describe the effect of the medicine palbociclib when given together with an aromatase inhibitor for treatment of breast cancer.
- Trial name
- NCT06307457
- Testing
- Palbociclib in combination with AI
- Where
- Denmark
- Volunteers
- 604 people
- Sponsor
- Pfizer
Type 1 Diabetes
Insulet Artificial Pancreas Early Feasibility Study
The purpose is to perform an early investigation on the safety and performance of an Automated Glucose Control (AGC) algorithm using the OmniPod® Insulin Management System and gather clinical data that will be used to make…
- Trial name
- NCT02897557
- Testing
- Insulet Artificial Pancreas (AP) System
- Where
- 4 sites in United States
- Volunteers
- 59 people
- Sponsor
- Insulet Corporation
Pancreas Cancer, Pancreas Cyst
ALateral Flow Assay to Detect QSOX1 Peptide in Patients With or at Risk for Pancreatic Cancer
Researchers have developed a new test to measure a protein QSOX1 that is found to be elevated in subjects with pancreas cancer. Researchers are looking to use this test to compare subjects with pancreas cancer and subjects…
- Trial name
- NCT04064034
- Testing
- Lateral Flow Assay (LFA)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Growth Hormone Deficiency
Gene Expression in Monocytes of Growth Hormone Deficient Children
The Growth hormone (GH) is mainly synthesized in the anterior portion of the pituitary gland and has an effect on different body areas.
- Trial name
- GEMGH (NCT04352712)
- Testing
- blood sampling
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Salerno
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