Clinical trials: Endocrine Disorders
Polycystic Ovary Syndrome, Insulin Resistance
Auricular Acupressure (AA) For Insulin Resistance in Women With Polycystic Ovary Syndrome
The present trial is a pilot study to investigate the effect of auricular acupressure on insulin resistance in women with PCOS.A total of 100 subjects will be enrolled into this study and will be randomized into two groups.
- Trial name
- NCT03546595
- Testing
- Auricular acupoints acupressure
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Heilongjiang University of Chinese Medicine
Diabetes Mellitus, Type 1
Keeping in Touch (KiT) With Youth as They Transition to Adult Type 1 Diabetes Care
The investigators are testing the effectiveness of an eHealth digital tool co-designed with patients and providers to improve diabetes self-efficacy in young adults as they transition to adult type 1 diabetes care.
- Trial name
- KiT (NCT05434754)
- Testing
- eHealth Tool
- Where
- 6 sites in Canada
- Volunteers
- 234 people
- Sponsor
- The Hospital for Sick Children
Type 1 Diabetes
Happy Bob App: A Preliminary Evaluation of Its Use in Youth With Diabetes
The goal of this clinical trial is to evaluate the impact of peer support via the Happy Bob phone app in youth with Type 1 Diabetes.
- Trial name
- NCT06412601
- Testing
- RPM, app
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Ovarian Cancer, Peritoneal Cancer
A Study of Single Agent Pemetrexed Disodium in Treating Patients With Recurrent or Persistent Ovarian or Primary Peritoneal Cancer
The primary purpose of this trial is to estimate the drug effect on tumors in patients with ovarian or primary peritoneal cancers. Patients will receive Pemetrexed every 21 days until disease progression or unacceptable toxicity.
- Trial name
- NCT00461786
- Testing
- pemetrexed
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Eli Lilly and Company
Diabetes Mellitus, Type 1
A Study of SIMPONI® to Arrest Beta-cell Loss in Type 1 Diabetes
The primary purpose of this study is to determine if golimumab can preserve beta-cell function in children and young adults with newly diagnosed Type 1 Diabetes (T1D).
- Trial name
- T1GER (NCT02846545)
- Testing
- Golimumab
- Where
- 33 sites in United States
- Volunteers
- 84 people
- Sponsor
- Janssen Research & Development, LLC
Thyroid Diseases
Outcomes of Thyroid Auto Transplantation Following Total Thyroidectomy in Benign Thyroid Disorders Protocol
the study aimed at evaluating efficacy of auto-transplantation of thyroid tissue after total thyroidectomy in benign thyroid disorders to keep the patient euthyroid with no need for life long hormone replacement therapy.
- Trial name
- NCT05930977
- Testing
- total thyroidectomy followed by thyroid auto transplantation
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Diabetes, Gestational, Obesity
Maternal GDM in Hispanic Youth: Risk for Obesity
Our studies are aimed at examining effects of intrauterine exposure to GDM on metabolic risks in Hispanic children. Our primary hypothesis predicts that intrauterine exposure to GDM will be associated with one or more of three…
- Conditions
- Diabetes, Gestational, Obesity, Insulin Resistance, Insulin Secretion
- Trial name
- NCT02668601
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Fragile X Syndrome, Angelman Syndrome
Parent and Infant Inter(X)Action Intervention (PIXI)
The objective is to develop and test, through an iterative process, an intervention to address and support the development of infants with a confirmed diagnosis of a neurogenetic disorder with associated developmental delays or…
- Conditions
- Fragile X Syndrome, Angelman Syndrome, Prader-Willi Syndrome, Dup15Q Syndrome
- Trial name
- NCT03836300
- Testing
- Parent-Infant Inter(X)action Intervention (PIXI)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- RTI International
Papillary Thyroid Carcinoma, Thyroid Cancer
Pattern and Surgical Outcome of Papillary Thyroid Cancer at Sohag University Hospitals
The aim of this study is to evaluate the clinicopathological pattern and surgical outcome of papillary thyroid carcinoma (PTC) at Sohag University Hospitals.
- Trial name
- NCT07823439
- Volunteers
- 30 people
- Sponsor
- Sohag University
Hypotonia-Cystinuria Syndrome, Muscle Hypotonia
PREPL in Health and Disease
Evaluation of PREPL activity in healthy controls and known or possible PREPL deficient patients
- Conditions
- Hypotonia-Cystinuria Syndrome, Muscle Hypotonia, Healthy Volunteers, Dwarfism, Growth Hormone Deficiency
- Trial name
- PHD (NCT02263781)
- Testing
- Blood draw, muscle biopsy
- Where
- Belgium
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Diabetic Ketoacidosis
Cerebral Edema in Pediatric Diabetic Ketoacidosis
The purpose of this trial is to compare two different rates of fluid administration during diabetic ketoacidosis (DKA) treatment in children to determine which fluid administration rate is more beneficial for brain metabolism and…
- Trial name
- NCT00629707
- Testing
- intravenous fluid treatment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Davis
Diabetes Mellitus, Type 1
Interventions to Prevent Adolescents With Type 1 Diabetes From Long-term Complications
The purpose of this study is to evaluate the effectiveness of diabetes management training combined with the method of Motivational Interviewing with elements of Cognitive Behaviour Therapy and E-mail support in the treatment of…
- Trial name
- NCT01520428
- Testing
- Motivational Interviewing, CBT and E-mail support
- Where
- Austria
- Volunteers
- 120 people
- Sponsor
- Medical University of Vienna
Vascular Diseases, Peripheral Artery Disease
RECCORD (Recording Courses of Vascular Diseases) Registry
The RECording COurses of vasculaR Diseases registry (RECCORD registry) is an observational, prospective, multicentre, all-comers registry platform.
- Conditions
- Vascular Diseases, Peripheral Artery Disease, Claudication, Critical Limb Ischemia
- Trial name
- RECCORD (NCT03448029)
- Where
- Germany
- Volunteers
- 6,000 people
- Sponsor
- Deutsche Gesellschaft für Angiologie, Gesellschaft für Gefäßmedizin e.V.
Pancreatic Neoplasm
Tight Glycemic Control by Artificial Pancreas
This study evaluated a closed-loop system providing continuous monitoring and strict control of perioperative blood glucose following pancreatic resection.
- Trial name
- NCT00657995
- Testing
- Artificial Pancreas (STG-22)
- Where
- Japan
- Volunteers
- 32 people
- Sponsor
- Kochi University
Hypertension, Diabetes Mellitus
Hypertension and Diabetes Mellitus Community Management Center(HAD-COME) Project
To develop and implement quality improvement programs for the treatment and management of hypertension and diabetes,and preventing and controlling hypertension and diabetes-related diseases in Chinese community.
- Trial name
- NCT04229628
- Testing
- No special intervention
- Where
- China
- Volunteers
- 100,000 people
- Sponsor
- Guangdong Provincial People's Hospital
Fertility Preservation, Ovarian Tissue Cryopreservation
Preservation of Ovarian Cortex Tissue in Girls With Turner Syndrome
Rationale: Infertility due is a major concern for girls with Turner syndrome (TS) and their parents. Physicians are often asked about possible options to preserve their fertility.
- Conditions
- Fertility Preservation, Ovarian Tissue Cryopreservation, Turner Syndrome, Live Birth
- Trial name
- NCT03381300
- Testing
- Ovarian tissue cryopreservation
- Where
- Netherlands
- Volunteers
- 106 people
- Sponsor
- Radboud University Medical Center
Testicular Neoplasms
Risk of Venous Thromboembolism in Patients Receiving First-Line Chemotherapy for Disseminated Germ Cell Tumours
Recent data (Srikanthan and Tran et al. JCO 2014, in press) have demonstrated that the presence of large retroperitoneal lymph node metastases on baseline staging scans (measuring >5cm in axial dimension) are associated with…
- Trial name
- G3 RPLN PBC (NCT04122430)
- Testing
- Review of Health Information
- Where
- Australia
- Volunteers
- 1,135 people, healthy volunteers welcome
- Sponsor
- Walter and Eliza Hall Institute of Medical Research
Diabetes Mellitus, Type 1
Effectiveness of a Combined mHealth-CBT Psychological Intervention to Improve Psychological Well-Being in Young Patients With T1D
Type 1 diabetes (T1D) can lead to psychological adjustments that impact the acceptance and management of this health condition, as well as the overall quality of life of patients, especially among the young.
- Trial name
- NCT06450730
- Testing
- Cognitive-Behavioral Therapy: face-to-face + app
- Where
- Spain
- Volunteers
- 122 people
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Diabetic Foot Ulcer
Longitudinal Study of Chronic Wounds Using Novel Wound Measurement Technologies
An open, non-randomised longitudinal study of diabetic foot ulcers receiving standardised treatment, over a 16 week period conducted at out-patient level, utilising novel optical wound measurement technologies.
- Trial name
- NCT02967900
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Michelson Diagnostics Ltd.
Type 1 Diabetes Mellitus, Continuous Glucose Monitor
Web-Based Intervention Designed to Educate and Improve Adherence Through Learning to Use Continuous Glucose Monitoring
The goal of this pilot study is to produce a high-quality, theory-driven, therapeutic, web-based intervention that provides extended training and peer support to adolescents and young adults with type 1 diabetes who are newly…
- Trial name
- IDEAL CGM (NCT03367351)
- Testing
- Web-Based Education, Social Support, Standard of Care
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Florida
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