Clinical trials: Endoscopic Therapy
Endoscopic Biliary Sphincterotomy, Bleeding
Antihemostatic Therapy and Endoscopic Biliary Sphincterotomy Induced Bleeding
The aim of the study is to observe the effects of antihemostatic therapy including nonsteroidal antiinflammatory, anticoagulant and antiaggregant therapy and other patient and procedure related factors on the risk of endoscopic…
- Trial name
- NCT01098617
- Where
- Turkey (Türkiye)
- Volunteers
- 350 people
- Sponsor
- Yuksek Ihtisas Hospital
Solid Cancer, Bronchial Endoscopy
Impact of Interventional Endoscopy on Quality of Life in Patients With Acute Respiratory Distress Due to Tumor Compression or Obstruction of the Lower Respiratory Tract
Bronchoscopic endoscopy has shown its effectiveness and reliability for the treatment (desobstruction or prothesis) of tumor-induced bronchial obstructions, particularly in the first few weeks.
- Conditions
- Solid Cancer, Bronchial Endoscopy, Therapeutic Bronchofiberscopy
- Trial name
- ENDoRA (NCT07051161)
- Testing
- bronchoscope
- Volunteers
- 60 people
- Sponsor
- University Hospital, Grenoble
Gastroesophageal Reflux Disease (GERD)
A Study of the Safety and Effectiveness of Rabeprazole for the Treatment of Gastroesophageal Reflux Disease (GERD) in Pediatric Patients
The purpose of the study is to access the effectiveness and safety of oral rabeprazole in the treatment of acid-related disorders in pediatric patients, focusing specifically on the manifestation of GERD (symptomatic and erosive…
- Trial name
- NCT00787891
- Testing
- rabeprazole
- Volunteers
- 127 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Pilonidal Sinus
Endoscopic Pilonidal Sinus Treatment (EPSIT) Versus Sinus Laser Closure (SiLaC) Versus Lay Open Technique
Aim of the work To compare Sinus Laser closure versus lay open technique versus Endoscopic pilonidal sinus treatment as regards recurrence rate, operative data, postoperative pain, intra and postoperative complications, healing…
- Trial name
- NCT04418336
- Testing
- Endoscopic Pilonidal sinus treatment (EPSIT) versus Sinus Laser Closure (SiLaC) versus lay open technique
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Rectal Cancer, Colo-rectal Cancer
Pre-therapeutic MRI Assessment of Early-Stage Rectal Cancer and Significant Rectal Polyps to Avoid Major Resectional Surgery
When a patient is diagnosed with a rectal (bowel) polyp or cancer, radiology doctors read MRI scans to describe how deeply the cancer invades into the bowel wall (this is the 'stage' of the cancer).
- Trial name
- PRESERVE (NCT04103372)
- Testing
- MRI scan, Radiologist training
- Where
- 23 sites in United Kingdom
- Volunteers
- 200 people
- Sponsor
- Imperial College London
Inflammatory Bowel Disease, Crohn Disease
Deep Endoscopic Remission Assessed by a Surrogate Biomarker in Patients With Inflammatory Bowel Disease
We hypothesize that the number of needed endoscopic procedure performed at IBD patients (adult and children), can be reduced by using an individualized algorithm of symptoms, blood and faecal biomarkers.
- Conditions
- Inflammatory Bowel Disease, Crohn Disease, Ulcerative Colitis
- Trial name
- NCT01861288
- Where
- Denmark
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Computer Assisted, Navigation
Computer Assisted Navigation on Endoscopic Sinus Surgery for Treatment of Sinonasal Polyposis
This study aimed to compare Endoscopic Sinus Surgery with and without image guidance, analyzing a number of parameters that can impact efficacy in cases of nasal polyposis.
- Conditions
- Computer Assisted, Navigation, Endoscopic Sinus Surgery, Sinonasal Polyposis
- Trial name
- NCT07575022
- Testing
- Endoscopic sinus surgery with Computer Assisted Navigation, Endoscopic sinus surgery
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Schistosomiasis Mansoni, Portal Hypertension
Treatment Schistosomal Portal Hypertension: Efficacy of Endoscopy or Surgery
Upper gastrointestinal bleeding (UGIB) is a major cause of morbidity and mortality in patients with portal hypertension secondary to schistosomiasis mansoni.
- Conditions
- Schistosomiasis Mansoni, Portal Hypertension, Upper Gastrointestinal Bleeding
- Trial name
- NCT01931826
- Testing
- Endoscopic treatment, Total EGDS+ endoscopy
- Where
- Brazil
- Volunteers
- 54 people
- Sponsor
- Universidade Estadual de Ciências da Saúde de Alagoas
Biliary Stricture, Chronic Pancreatitis
Endoscopic Treatment of Biliary Stricture Caused by Chronic Pancreatitis
Benign biliary strictures can be endoscopically treated with plastic or self-expandable metal stents (SEMS). The purpose of the prospective randomized study is to compare the safety and feasibility of covered SEMS with multiple…
- Trial name
- NCT01085747
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- Helsinki University Central Hospital
Pilonidal Sinus
Endoscopic Pilonidal Sinus Treatment With Additional Crystalized Phenol
This study presents 23 sacrococcygeal pilonidal disease cases treated with endoscopic cleaning and fulguration of pilonidal sinus inner surfaca followed by application of crystallized phenol into the sinus.
- Trial name
- EPSITCRYSP (NCT02277340)
- Testing
- EAPA
- Volunteers
- 23 people
- Sponsor
- Ankara University
Gastrointestinal Stromal Tumor
the Laparoscopic and Endoscopic Cooperative Surgery of Gastrointestinal Stromal Tumor
Gastric stromal tumor is a gastrointestinal mesenchymal tumor with malignant differentiation potential, the incidence increased year by year. The surgical resection is the primary treatment for it.
- Trial name
- NCT02763748
- Testing
- Laparoscopic endoscopy combined surgery, laparoscopic and endoscopic cooperative surgery, Single-arch laparoscopic and endoscopic cooperative surgery
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Sedation Complication
Comparison of High-Flow Nasal Cannula Oxygen Application and Classic Nasal Cannula Oxygen Application
Recently, sedation practices have increased for diagnostic and interventional procedures for children in non-operating rooms. On the other hand, the rate of respiratory complications especially in non-operating room sedation…
- Trial name
- NCT04472273
- Testing
- high-flow nasal cannula / classic nasal cannula
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Kocaeli Derince Education and Research Hospital
Lumbar Herniated Disc
US-MR Image Fusion-guided Percutaneous Transforaminal Endoscopic Discectomy for the Treatment of Lumbar Disc Herniation
The purpose of this study is to evaluate the feasibility and efficacy of US-MR image fusion-guided percutaneous transforaminal endoscopic discectomy for the treatment of lumbar disc herniation
- Trial name
- NCT03403244
- Testing
- US-MR image fusion-guided PTED, fluoroscopy-guided PTED
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Colorectal Cancer
Use of Telehealth In-home Messaging to Improve GI (Gastrointestinal) Endoscopy Completion Rates
Low endoscopy completion rates are a major problem in the VA, causing delay or failure to receive essential care, increased clinic wait times, lost capacity, increased costs, thus limiting endoscopic screening for colorectal…
- Trial name
- GIVER (NCT00310362)
- Testing
- Use of Interactive Voice Response (IVR) system to improve adherence to GI appointments and prep procedures
- Where
- United States
- Volunteers
- 3,610 people
- Sponsor
- VA Office of Research and Development
Stage I Esophageal Adenocarcinoma, Stage II Esophageal Adenocarcinoma
Clinical Study of Time Optimizing of Endoscopic Photodynamic Therapy on Esophageal and/or Gastric Cardiac Cancer
The therapy of photofrin PDT was effective in improving life quality of patients with advanced esophageal and/or gastric cardiac cancer and the time optimizing for employing laser irradiation was of great importance.The purpose…
- Conditions
- Stage I Esophageal Adenocarcinoma, Stage II Esophageal Adenocarcinoma, Stage III Esophageal Adenocarcinoma, Stage I Esophageal Squamous Cell Carcinoma
- Trial name
- NCT02628665
- Testing
- photosensitizer(photofrin), 630 nm laser irradiation (DIOMED)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The First Affiliated Hospital of Henan University of Science and Technology
Endotracheal Intubation, Gastrointestinal Endoscopy
Application of Lateral Position Digestive Endoscopy-Guided Endotracheal Intubation in Anesthesia for Endoscopic Diagnosis and Therapy
This case series study evaluated whether placing a breathing tube using a camera (gastrointestinal endoscope) is safe and effective for patients lying on their left side during stomach and intestine exams under anesthesia.
- Conditions
- Endotracheal Intubation, Gastrointestinal Endoscopy, Airway Management, Lateral Position
- Trial name
- NCT06990490
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Changlong Qiao
Chronic Pancreatitis
Endoscopic Versus Surgical Treatment of Chronic Pancreatitis
Chronic pancreatitis is a progressive inflammatory disease of the pancreas characterized by destruction of pancreatic parenchyma and subsequent fibrosis.
- Trial name
- NCT01520675
- Testing
- surgery, Endoscopic therapy
- Where
- India
- Volunteers
- 50 people
- Sponsor
- All India Institute of Medical Sciences
Variceal Bleeding, Cirrhosis
Comparison of Terlipressin, Somatostatin, and Octreotide for Control of Variceal Bleeding
This study is performed to compare the efficacy of terlipressin, somatostatin, and octreotide in patients with variceal bleeding for the control of variceal bleeding in combination with endoscopic therapy.
- Trial name
- NCT00966355
- Testing
- Terlipressin, Somatostatin, Octreotide
- Where
- South Korea
- Volunteers
- 1,034 people
- Sponsor
- Korea University
Crohn Disease
Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease
Crohn's disease (CD) is a condition that causes inflammation (swelling, redness) of the lining and wall of the small intestine, large intestine, or both.
- Trial name
- CAMEO (NCT05781152)
- Testing
- Anti-TNF therapy
- Where
- 26 sites in United States, Canada
- Volunteers
- 1,270 people
- Sponsor
- Connecticut Children's Medical Center
Peptic Ulcer Hemorrhage
Resolution Endoclips Vs Epinephrine Injection and Heater Probe
To compare the efficacy of a novel endoscopic clipping device(Resolution Clip™) and conventional epinephrine injection and heater probe thermocoagulation in control of peptic ulcer bleeding and prevention of recurrent bleeding
- Trial name
- NCT00165009
- Testing
- Resolution clip (endo-clipping device)
- Where
- China
- Volunteers
- 103 people
- Sponsor
- Chinese University of Hong Kong