Clinical trials: Endoscopy, Digestive System
Biliary Disease, Pancreatitis
Los Angeles Prospective GI Biliary and EUS Series
Endoscopic retrograde cholangiopancreatography and endoscopic ultrasound are increasingly being used to manage complex disease of the bile duct, pancreas and cancer.
- Conditions
- Biliary Disease, Pancreatitis, Gastrointestinal Neoplasms
- Trial name
- NCT02196935
- Testing
- clinical course
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- University of Southern California
Endoscopic Surgical Procedure
Percutaneous Sigmoid Fixation For Management Of Recurrent Sigmoid Volvulus
The investigators included all patients who were presented to emergency department with recurrent sigmoid volvulus at Zagazig University hospital between (August 2024 to August 2025).
- Trial name
- NCT07155304
- Testing
- percutaneous sigmoid colon fixation
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Laryngeal Cleft, Dysphagia
Injection Versus Suture Repair of Laryngeal Clefts
The purpose of the study is to learn more about a procedure that may be helpful for the participant's swallowing issues. The investigators are hoping to find out if one type of procedure is the same or better than another type of…
- Trial name
- NCT07057258
- Testing
- Endoscopic suture repair, Injection laryngoplasty
- Where
- 2 sites in United States
- Volunteers
- 128 people
- Sponsor
- Oregon Health and Science University
Biliary Stricture, Chronic Pancreatitis
Endoscopic Treatment of Biliary Stricture Caused by Chronic Pancreatitis
Benign biliary strictures can be endoscopically treated with plastic or self-expandable metal stents (SEMS). The purpose of the prospective randomized study is to compare the safety and feasibility of covered SEMS with multiple…
- Trial name
- NCT01085747
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- Helsinki University Central Hospital
Liver Transplantation
Endoscopic Evaluation in Transplantation Candidates
In consideration of the limited supply of donor organs, the careful selection of transplant candidates is essential to optimize patient outcome after transplantation.
- Trial name
- NCT00990470
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- Hannover Medical School
Oesophageal Cancer
Cytosponge™ for Post-Chemoradiation Surveillance of Oesophageal Cancer
This is a feasibility study testing the use of the Cytosponge™ device in patients with known oesophageal cancer treated with pre-operative or definitive chemoradiation.
- Trial name
- CYTOFLOC (NCT03529669)
- Testing
- Cytosponge™
- Where
- 11 sites in United Kingdom
- Volunteers
- 41 people
- Sponsor
- University of Oxford
Acute Bleeding Esophageal Varices, Portal Hypertension
A Trial of Somatostatin With Endoscopic Variceal Ligation (EVL) in Control of Acute Variceal Bleeding
Background: Efficacy of endoscopic variceal sclerotherapy in achieving initial control of acute variceal bleeding and five-day haemostasis has been shown to significantly improve when vasoactive drug is added.
- Conditions
- Acute Bleeding Esophageal Varices, Portal Hypertension, Cirrhosis
- Trial name
- AVB-EVL+S (NCT01267669)
- Testing
- Somatostatin
- Where
- India
- Volunteers
- 61 people
- Sponsor
- Govind Ballabh Pant Hospital
Peptic Ulcer Hemorrhage
Resolution Endoclips Vs Epinephrine Injection and Heater Probe
To compare the efficacy of a novel endoscopic clipping device(Resolution Clip™) and conventional epinephrine injection and heater probe thermocoagulation in control of peptic ulcer bleeding and prevention of recurrent bleeding
- Trial name
- NCT00165009
- Testing
- Resolution clip (endo-clipping device)
- Where
- China
- Volunteers
- 103 people
- Sponsor
- Chinese University of Hong Kong
Celiac Disease
Capsule Endoscopy in Newly Diagnosed Patients of Celiac Disease
Celiac Disease is an autoimmune disorder that affects approximately 1% of the world's population 1. The diagnosis of CD requires clinical, histopathological and serological factors 2.
- Trial name
- NCT03731806
- Where
- Pakistan
- Sponsor
- Tazeen Rasheed
Esophageal Achalasia
Short Versus Long Submucosal Tunneling in Per-oral Endoscopic Myotomy (POEM) for Type II Achalasia.
this study is prospective , randomized and interventional ,will be performed on 50 patients to compare the clinical utility , safety profile and postoperative recovery metrics between short and long per-oral endoscopic myotomy …
- Trial name
- NCT07686471
- Testing
- per-oral endoscopic myotomy
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Sedation
Sedation During Pediatric Diagnostic Gastrointestinal Endoscopy Gastrointestinal Endoscopy
comparison between propofol-fentanyl and propofol-ketamine for sedation in pediatric diagnostic gastrointestinal endoscopy.
- Trial name
- NCT03235609
- Testing
- Fentanyl, Ketamine
- Volunteers
- 60 people
- Sponsor
- Assiut University
Portal Hypertension
Endoscopic Variceal Ligation (EVL)+ Drugs Versus Endoscopic Variceal Ligation (EVL) Alone For Secondary Prophylaxis
Background: Both endoscopic variceal ligation (EVL) and propranolol are valuable methods for secondary prophylaxis of variceal bleeding. Addition of ISMN to propranolol improves the efficacy of drug therapy.
- Trial name
- Secondary (NCT00766805)
- Testing
- EVL + Propranolol + Isosorbide 5 mononitrate, EVL alone
- Where
- India
- Volunteers
- 177 people
- Sponsor
- Govind Ballabh Pant Hospital
Upper and Lower Gastrointestinal Bleeding
Clinical and Endoscopic Pattern in Children Presented With Upper and Lower Gastrointestinal Bleeding Insohag University Hospital
Gastrointestinal bleeding (GIB) is one of the most common conditions in the emergency department. Upper GIB is a major problem that has been decreasing over the past 20 years but still has high mortality rate.
- Trial name
- NCT06047873
- Testing
- Endoscopy
- Volunteers
- 30 people
- Sponsor
- Sohag University
Chronic Pancreatitis
Balloon Catheter vs. Basket Catheter in Pancreatic Duct Stone Clearance
The aim of the study is to compare the safety and efficacy of the basket catheter with that of the balloon catheter for endoscopic extraction of pancreatic stones.
- Trial name
- NCT05888012
- Testing
- basket catheter, balloon catheter
- Where
- China
- Volunteers
- 6,493 people
- Sponsor
- Changhai Hospital
Early Gastric Cancer
Laparoscopic-endoscopic Surgery Assisted Sentinel Lymph Node Navigation Surgery for Early Gastric Cancer
This study is to evaluate the safety and efficacy of dual-endoscope assisted sentinel lymph node navigation surgery for early gastric cancer (EGC).
- Trial name
- NCT07615374
- Testing
- Laparoscopic-endoscopic cooperative surgery (LECS) Assisted Sentinel Lymph Node Navigation Surgery
- Where
- 2 sites in China
- Volunteers
- 36 people
- Sponsor
- Jilin University
Gerd, Esophagogastric Junction
Sedation Depth and EGJ Endoscopic Grading: A Randomized Controlled Trial
Brief Study Summary: This prospective randomized controlled trial evaluates the impact of procedural sedation depth on the American Foregut Society (AFS) endoscopic grading of esophagogastric junction (EGJ) integrity and its…
- Conditions
- Gerd, Esophagogastric Junction, American Foregut Society Classification
- Trial name
- EGJ-SED (NCT07891455)
- Testing
- Upper gastrointestinal endoscopy
- Where
- Egypt
- Volunteers
- 192 people
- Sponsor
- Mohamed Abd El-Raouf Tawfik
Laryngitis, Reflux
Inter-rater Reliability of the Reflux Finding Score Among Gastroenterologists
Title: Inter-rater reliability of the reflux finding score based on endoscopic laryngeal findings in the diagnosis of laryngopharyngeal reflux disease Participants: Voluntary participants after invitation among members (a total…
- Trial name
- NCT02048449
- Volunteers
- 21 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Pancreatic Cancer
The Accurateness of Endoscopic Ultrasound Elastography in the Guidance of EUS-FNA in Solid Pancreatic Lesions
To evaluate the role and effectiveness of EUS elastography as the guidance for direction of the site of fine needle aspirate (FNA) for tissue acquisition of solid pancreatic lesions
- Trial name
- NCT04148755
- Testing
- Endoscopic ultrasound guided fine needle aspirate
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Gastro-Intestinal Disorder
Endoscopic Retrograde Cholangiopancreatography
The risk of post-endoscopic retrograde cholangiopancreatography(ERCP) pancreatitis(PEP) is influenced by patient and procedure-related factors.
- Trial name
- NCT07490132
- Testing
- Patients undergoing ERCPs at Methodist Dallas Medical Center
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Methodist Health System
Failure to Thrive, Endoscope
Role of Gastroinestinal Endoscopy in Pediatric Failure to Thrive
This study aims to evaluate the diagnostic role of gastrointestinal endoscopy in children presenting with failure to thrive and its correlation with histopathology and other diagnostic modalities.
- Trial name
- NCT07160387
- Volunteers
- 50 people
- Sponsor
- Assiut University