Clinical trials: Endoscopy, Digestive System
Crohn Disease
Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease
Crohn's disease (CD) is a condition that causes inflammation (swelling, redness) of the lining and wall of the small intestine, large intestine, or both.
- Trial name
- CAMEO (NCT05781152)
- Testing
- Anti-TNF therapy
- Where
- 26 sites in United States, Canada
- Volunteers
- 1,270 people
- Sponsor
- Connecticut Children's Medical Center
Biliary Disease, Pancreatitis
Los Angeles Prospective GI Biliary and EUS Series
Endoscopic retrograde cholangiopancreatography and endoscopic ultrasound are increasingly being used to manage complex disease of the bile duct, pancreas and cancer.
- Conditions
- Biliary Disease, Pancreatitis, Gastrointestinal Neoplasms
- Trial name
- NCT02196935
- Testing
- clinical course
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- University of Southern California
Bowel Disease, Crohn Disease
Development of New Diagnostic Tools in Capsule Endoscopy
Patients participating to this study will provide images and videos of capsule endoscopy to train, tune and evaluate technological bricks of artificial intelligence solutions, in order to improve diagnostic performances of the…
- Conditions
- Bowel Disease, Crohn Disease, Celiac Disease, Chronic Diarrhea
- Trial name
- NOCE (NCT06152289)
- Where
- France
- Volunteers
- 10,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Portal Hypertension
Clinical,Endoscopic and Radiological Assessment of Portal Hypertension in Children With Chronic Liver Diseases
Portal hypertension is a significant cause of morbidity and mortality in children with chronic liver disease and portal vein obstruction.
- Trial name
- NCT06097715
- Testing
- upper gastrointestinal endoscopy, 1- Complete blood count 2- Coagulation profile
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sohag University
Rectal Prolapse
TEM Assisted Perineal Rectopexy in Treatment of Rectal Prolapse
Curvilinear incision in the postanal space, through the intersphincteric plane, insertion of Proctoscope of TEM technique and dissection till sacral promontory, insertion of mesh between the rectum and sacrum, post anal repair…
- Trial name
- NCT02609555
- Testing
- TEM perineal rectopexy
- Where
- Egypt
- Volunteers
- 7 people
- Sponsor
- Mansoura University
Gerd, Esophagogastric Junction
Sedation Depth and EGJ Endoscopic Grading: A Randomized Controlled Trial
Brief Study Summary: This prospective randomized controlled trial evaluates the impact of procedural sedation depth on the American Foregut Society (AFS) endoscopic grading of esophagogastric junction (EGJ) integrity and its…
- Conditions
- Gerd, Esophagogastric Junction, American Foregut Society Classification
- Trial name
- EGJ-SED (NCT07891455)
- Testing
- Upper gastrointestinal endoscopy
- Where
- Egypt
- Volunteers
- 192 people
- Sponsor
- Mohamed Abd El-Raouf Tawfik
Infection Control
Risk Assessment of Indirect Exposure to the Environment in the Gastrointestinal Endoscopy Center
Study objective: To clarify the risk of exposure to indirect contact and transmission of environmental objects during digestive endoscopy diagnosis and treatment for patients and medical staff, simulating by using Vitamin B2…
- Trial name
- NCT05321043
- Testing
- Vitamin B2 labeling
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking Union Medical College Hospital
Constipation, Hirschsprung Disease
Endoscopic Mucosal Resection for the Diagnosis of a-Ganglionosis, a Controlled Prospective Trial (EDGE Trial)
Patients undergoing routine rectal suction biopsy will undergo as part of the study an additional Endoscopic mucosal resection. The biopsy results will also be correlated with patient's clinical data including clinical history…
- Trial name
- EDGE (NCT01515501)
- Testing
- Endoscopic mucosal resection (EMR)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Massachusetts General Hospital
Early Gastric Cancer
the Train the Trainer (TTT) Plan, to Improve the Young Endoscopist's Ability to Find the Early Gastric Cancer
AIM Verified if the first stage of the Train the trainer (TTT)plan could improve the young endoscopist's ability to detect the early gastric cancer（EGC）. METHOD 1.
- Trial name
- NCT02385578
- Testing
- an educational intervention
- Volunteers
- 16,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Human Immunodeficiency Virus
Relationship of Tenofovir With HIV-1 Suppression in ex Vivo Tissue in Adolescents
Microbicides are topical medicines that can prevent infection by Human Immunodeficiency Virus (HIV). Microbicide medicine has yet to be studied in adolescents, a key group that is becoming infected with HIV all over the world.
- Trial name
- NCT02134431
- Testing
- flexible sigmoidoscopy or colonoscopy with biopsies
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Tracheoesophageal Fistula, Esophageal Atresia With Tracheo-esophageal Fistula
Camera-based Endoscopy Allows Spontaneous Breathing Diagnostic Management in Neonates With Tracheoesophageal Fistula
The investigators aim to compare rigid tracheoscopy versus flexible tracheo-video-endoscopy in neonates requiring diagnostic assessment before undergoing a congenital tracheoesophageal fistula repair.
- Trial name
- CBESB (NCT07687628)
- Testing
- tracheoscopy performed with rigid optical tracheoscopy, flexible video endoscopy of trachea
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Papa Giovanni XXIII Hospital
Laryngeal Cleft, Dysphagia
Injection Versus Suture Repair of Laryngeal Clefts
The purpose of the study is to learn more about a procedure that may be helpful for the participant's swallowing issues. The investigators are hoping to find out if one type of procedure is the same or better than another type of…
- Trial name
- NCT07057258
- Testing
- Endoscopic suture repair, Injection laryngoplasty
- Where
- 2 sites in United States
- Volunteers
- 128 people
- Sponsor
- Oregon Health and Science University
C.Medical Procedure; Digestive System, Disorder of Upper Gastrointestinal Tract
Lidocaine Spray on an Endoscope to Improve Tolerance to Endoscopy
The investigators tested whether a new method which additional lidocaine spray on the tip of endoscope can increase the tolerance of examinee during endoscopy than conventional pharyngeal anesthesia alone.
- Conditions
- C.Medical Procedure; Digestive System, Disorder of Upper Gastrointestinal Tract, Tolerance
- Trial name
- NCT02307773
- Testing
- Case Group
- Where
- South Korea
- Volunteers
- 497 people
- Sponsor
- Cheju Halla General Hospital
Celiac Disease
Capsule Endoscopy in Newly Diagnosed Patients of Celiac Disease
Celiac Disease is an autoimmune disorder that affects approximately 1% of the world's population 1. The diagnosis of CD requires clinical, histopathological and serological factors 2.
- Trial name
- NCT03731806
- Where
- Pakistan
- Sponsor
- Tazeen Rasheed
Liver Cirrhosis, Esophageal and Gastric Varices
Non-invasive Prediction of Esophageal Varices in Liver Cirrhosis: A Multicenter Observational Study
Esophageal variceal bleeding is one of the most lethal complications of liver cirrhosis. In the early stage of liver cirrhosis, the prediction of esophageal varices is very important for guiding the clinical decision making of…
- Trial name
- NCT02593799
- Testing
- Endoscopy
- Where
- 17 sites in China
- Volunteers
- 363 people
- Sponsor
- General Hospital of Shenyang Military Region
Preoperative Fasting
Gastric Emptying After a Yoghurt Breakfast in Children: a Pilot Study
Children are asked to fast before anaesthesia to reduce the amount of material remaining in the stomach. Prolonged fasting can cause hunger, thirst and discomfort.
- Trial name
- PREFACT (NCT07866014)
- Testing
- Three-hour fasting after yoghurt breakfast, Four-hour fasting after yoghurt breakfast
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Baskent University Ankara Hospital
Rejection of an Intestine Transplant
Surveillance of Allograft Rejection After Intestinal Transplantation Using Endoscopy
Intestinal failure (IF) which are characterized by inadequate maintenance of nutrition via normal intestinal function comprises a group of disorders with many different causes.
- Trial name
- NCT03616548
- Testing
- Endoscopic surveillance
- Where
- Taiwan
- Volunteers
- 12 people
- Sponsor
- Far Eastern Memorial Hospital
Barrett Esophagus, Barrett Esophagus Adenocarcinoma
"Less-is-more in Barrett-surveillance" Care Evaluation of Barrett's Patients With Low-Risk in Whom Endoscopic Surveillance is Stopped. The BLISS Project.
Rationale: Until recently, the conventional strategy outlined by both national and international guidelines for managing non-dysplastic (ND) Barrett esophagus (BE), involved endoscopic surveillance at 3 to 5 year intervals…
- Trial name
- BLISS (NCT06803147)
- Testing
- Discontinued endoscopic surveillance
- Where
- Netherlands
- Volunteers
- 3,156 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Sedation Complication
Comparison of High-Flow Nasal Cannula Oxygen Application and Classic Nasal Cannula Oxygen Application
Recently, sedation practices have increased for diagnostic and interventional procedures for children in non-operating rooms. On the other hand, the rate of respiratory complications especially in non-operating room sedation…
- Trial name
- NCT04472273
- Testing
- high-flow nasal cannula / classic nasal cannula
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Kocaeli Derince Education and Research Hospital
Familial Adenomatous Polyposes, Duodenal Polyposis
Endoscopic Evaluation of Duodenal Polyposis in Patients With Familial Adenomatous Polyposis (FAP)
Familial adenomatous polyposis (FAP) is an autosomal dominant genetic disorder that predisposes to a number or malignant disorders [1,2].
- Conditions
- Familial Adenomatous Polyposes, Duodenal Polyposis, Duodenal Cancer
- Trial name
- NCT03346980
- Testing
- Esophagogastroduodenoscopy
- Where
- Denmark
- Volunteers
- 36 people
- Sponsor
- Copenhagen University Hospital, Hvidovre