Clinical trials: Engorgement
Glaucoma
Results of Mass Switch From Latanoprost to Travoprost
Prostaglandin analogs are a leading class of glaucoma drugs with a proven safety and efficacy for controlling IOP. They include latanoprost, bimatoprost, travoprost and unoprostone.
- Trial name
- NCT00347126
- Where
- Singapore
- Volunteers
- 372 people
- Sponsor
- Singapore National Eye Centre
Cataract, Postoperative Complications
Validation of an Artificial Intelligence System for Postoperative Management of Cataract Patients
Cataract surgery is the current standard of management for cataract patients, which is typically succeeded by a postoperative follow-up schedule.
- Conditions
- Cataract, Postoperative Complications, Artificial Intelligence
- Trial name
- NCT04138771
- Testing
- An artificial intelligence system for postoperative management of cataract patients
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Sun Yat-sen University
Septic Shock, Fluid Resuscitation
Evolution of Tissue Perfusion and Venous Congestion Markers in Fluid-Responsive Septic Shock Patients
Septic shock remains a leading cause of mortality in intensive care, and while fluid resuscitation (FR) is a cornerstone of early management, its benefit-risk balance is highly variable.
- Conditions
- Septic Shock, Fluid Resuscitation, Congestion, Venous
- Trial name
- FLUID-IMPACT (NCT06958809)
- Testing
- Echography
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Hospital Ambroise Paré Paris
Coronary Artery Disease, Myocardial Ischemia
Comparison of Hyperemic Efficacy Between Nicorandil and Adenosine for Fractional Flow Reserve (FFR) Measurement
The purpose of this study is to evaluate the efficacy of nicorandil in the achievement of maximal coronary hyperemia compared with adenosine.
- Trial name
- NCT01331902
- Testing
- Maximal Hyperemia with Adenosine Followed by Nicorandil, Maximal Hyperemia with Nicorandil Followed by Adenosine
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Seoul National University Hospital
Chronic Obstructive Pulmonary Disease, Endothelial Dysfunction
Micro-doses of Physical Activity for COPD
Chronic obstructive pulmonary disease (COPD) is a disease of the lungs that makes it hard for people to breath. Those with COPD spend considerably more time sitting and lying and less time performing physical activity than…
- Conditions
- Chronic Obstructive Pulmonary Disease, Endothelial Dysfunction, Vascular Stiffness, Hypertension
- Trial name
- COPD (NCT05553223)
- Testing
- Microdoses of activity
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Acute Heart Failure (AHF), Fluid Over-load
Training Medical Residents in the Use of the Venous Excess UltraSound (VExUS) Score for Bedside Volume Assessment.
This randomized controlled trial evaluates the effectiveness of two training approaches (in-person versus remote) for teaching medical residents to apply the Venous Excess Ultrasound (VExUS) score for bedside volume assessment in…
- Conditions
- Acute Heart Failure (AHF), Fluid Over-load, Congestion, Congestion, Venous
- Trial name
- NCT07541768
- Testing
- In-person VExUS Training Program, Remote VExUS Training Program, No intervention
- Where
- Switzerland
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Pterygium
Manifestations of Ocular Irritation Following Pterygium Excision With Sutures Fixed Conjunctival Autograft
In this work, the manifestations of ocular irritation associated with vicryl 8/0 sutures fixed conjunctival auto-graft in pterygium patients were evaluated.
- Trial name
- NCT05164900
- Testing
- pterygium excision with sutures fixed conjunctival auto-graft
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Tanta University
Endothelial Function (Reactive Hyperemia)
MOVING - MOtiVation, INtervention and Vascular chanGe
Background: The impact of demographic changes on workplace has increased the importance of effective occupational preventive health programs.
- Trial name
- MOVING (NCT01919632)
- Testing
- health-behavior seminar and endurance exercise
- Where
- 2 sites in Germany
- Volunteers
- 330 people
- Sponsor
- Technical University of Munich
Irreversible Pulpitis, Reversible Pulpitis
In Vivo Pulp Thermal Changes During Different Slenderization Techniques
The goal of this study is to learn about the temperature rise inside the living part of a tooth (the pulp) during different ways of removing a small amount of enamel (the hard outer layer of the tooth), a procedure called…
- Conditions
- Irreversible Pulpitis, Reversible Pulpitis, Thermal Injury, Pulp Hyperemia
- Trial name
- IPR (NCT07391124)
- Testing
- High-Speed Air-Driven Drill (Airotor and Bur), Orthodontic IPR Kit (Oscillating System)
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Cardiovascular Risk Factor, Endothelial Dysfunction
Interrupting Sitting With High Intensity Exercise on Vascular Function in Adolescents Before and After a Mixed Meal
This study aims to investigate the effect of interrupting a three hour bout of prolonged sitting with high intensity interval exercise on lower limb blood vessel function in adolescents before and after a mixed meal challenge.
- Trial name
- NCT04337385
- Testing
- Interrupting 3 hours of prolonged sitting with high intensity interval exercise, 3 hours of prolonged sitting
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Hyperemia
Safety of Brimonidine Tartrate Ophthalmic Solution in a Population of Pediatric, Adult, and Geriatric Participants
To compare the safety and tolerability of brimonidine tartrate ophthalmic solution 0.025% versus its vehicle in a population of pediatric, adult, and geriatric participants.
- Trial name
- NCT01959243
- Testing
- Brimonidine Tartrate, Vehicle, Sodium Fluorescein
- Where
- 4 sites in United States
- Volunteers
- 507 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Anesthesia; Functional
Unwanted Penile Engorgement in Pediatric Patients Under Anesthesia.
Penile engorgement during intraoperative period is of rare occurrence however when do happens, leads to difficulty in performing and even cancellation of elective urogenital surgery.
- Trial name
- NCT03438253
- Testing
- spinal anaesthesia
- Volunteers
- 386 people
- Sponsor
- Aligarh Muslim University
Coronary Artery Disease, Myocardial Ischemia
Comparison of Hyperemic Efficacy Between Central and Peripheral Adenosine Infusion for Fractional Flow Reserve (FFR) Measurement
The purpose of this study is to evaluate the safety and effectiveness of the peripheral IV continuous infusion without the insertion of central venous vascular access method in the achievement of steady-state maximal coronary…
- Trial name
- NCT01070420
- Testing
- FFR via central venous line, FFR via peripheral venous line
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Seoul National University Hospital