Clinical trials: Epidural
Cesarean
Cesarean Postoperative Pain Satisfaction
Hypothesis: There is no significant difference in Cesarean patients' perceptions of overall pain management satisfaction between methods used for postoperative pain management.
- Trial name
- NCT00922142
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Saint Elizabeth Regional Medical Center
Stress Response, Hemodynamic Changes
Stress Response and Hemodynamic Changes Associated With Intrathecal Anesthesia Versus Caudal Epidural Anesthesia in Infants Undergoing Laparoscopic Inguinal Herniorrhaphy
The aim of this work was to assess stress response and hemodynamic changes associated with intrathecal anesthesia versus caudal epidural anesthesia in infants undergoing laparoscopic inguinal herniorrhaphy.
- Conditions
- Stress Response, Hemodynamic Changes, Intrathecal Anesthesia, Caudal Epidural Anesthesia
- Trial name
- NCT06909396
- Testing
- General anesthesia, Intrathecal Anesthesia, Caudal block
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Tanta University
Anesthesia, Caudal, Pediatrics
Pediatric Caudal Injection Volume on Optic Nerve Sheath Diameter and Cerebral Oxygenation
Caudal anesthesia is a commonly used neuraxial anesthesia method for children. Injection of a certain volume of fluid into the epidural space for cauda anesthesia may push some cerebrospinal fluid towards the head, which may lead…
- Conditions
- Anesthesia, Caudal, Pediatrics, Elevated Intracranial Pressure
- Trial name
- NCT04491032
- Testing
- Caudal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Aybike Onur Gönen
Postoperative Pain
On-Q Pump vs Epidural for Postoperative Pain Control in Children
Open abdominal and pelvic surgery or thoracotomy (open chest surgery) is frequently performed for tumor excision in children. Post-operative pain management regimens are often at the discretions of the attending surgeon and may…
- Trial name
- NCT03496259
- Testing
- On-Q pump, Epidural catheter
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Baylor College of Medicine
Spinal and Epidural Anaesthesia-Induced Headache During Pregnancy
Establishment of a Predictive Model for Post-dural Puncture Headache
The goal of this clinical trial is to establish a predictive model for post-dural puncture headache. The main questions it aims to answer are: Changes in intracranial pressure after spinal puncture (or lumbar puncture).
- Trial name
- NCT06800859
- Testing
- Supplement fluids
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Yilin Zhao
Breakthrough Pain
PIEB Compared With CEI on Breakthrough Pain in Nulliparous Women
The goal of this randomized controlled trial is to examine the impact of programmed intermittent bolus epidural analgesia technique on the incidence of breakthrough pain during labor in nulliparous women compared to continuous…
- Trial name
- NCT06494280
- Testing
- programmed intermittent Bolus epidural analgesia, continuous epidural infusion
- Where
- Israel
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Holy Family Hospital, Nazareth, Israel
Analgesia
Postoperative Analgesia by Epidural vs IV Ketamine Concurrent With Caudal Anesthesia in Pediatric Orthopedic Surgery
Preemptive analgesia can improve postoperative pain management. Ketamine may prevent central sensitization during surgery and result in preemptive analgesia.
- Trial name
- NCT00532662
- Testing
- S(+)-ketamine
- Where
- 2 sites in Iran
- Volunteers
- 40 people
- Sponsor
- Tehran University of Medical Sciences
Anesthesia
Chloroprocaine for Continuous Epidural Analgesia in Neonates and Infants
This a study to retrospectively review our experience with the use of chloroprocaine for postoperative epidural infusions in neonates and infants.
- Trial name
- NCT02207855
- Testing
- Chloroprocaine
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Joseph D. Tobias
Labor Pain
Programmed Intermittent Epidural Bolus for Labor Analgesia During First Stage of Labor 2
Brief Summary: Until recently, at Mount Sinai Hospital, epidural analgesia for labor pain was delivered with a pump that could only provide continuous infusion of the freezing medication in combination of pushes of medication…
- Trial name
- NCT02758405
- Testing
- Bupivacaine, Fentanyl, Infusion pump
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Bone Tumor
The Epidural Anesthesia on the Intra-operative and Post-operative Amount of Bleeding Post Lower Limb Salvage Surgery
Epidural anesthesia is a very useful tool in lower limb salvage surgery, which helps pain control intra and more importantly post-operative pain.
- Trial name
- NCT01679691
- Testing
- epidural anesthesia
- Where
- Egypt
- Sponsor
- Children's Cancer Hospital Egypt 57357
Traumatic Brain Injury
Internet-based Interacting Together Everyday, Recovery After Childhood TBI (I-InTERACT)--RRTC
The purpose of this study is to test two on-line interventions for families of young children who have experienced moderate or severe traumatic brain injury (TBI).
- Trial name
- I-InTERACT (NCT01214694)
- Testing
- Internet-based Interacting Together Everyday: Recovery After Childhood TBI (I-InTERACT), Internet-based-Interacting Together Everyday, Recovery after Childhood TBI Express (I-InTERACT Express), Internet Resources Comparison (IRC)
- Where
- 5 sites in United States
- Volunteers
- 117 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Pain
Intermittent Epidural Bolus Versus Epidural Infusion for Posterior Spinal Fusion After Adolescent Idiopathic Scoliosis
Patient-controlled Intermittent epidural bolus versus epidural infusion for posterior spinal fusion after adolescent idiopathic scoliosis. Scoliosis surgery is commonly performed in adolescent due to idiopathic scoliosis.
- Trial name
- NCT02669004
- Testing
- Intermittent bolus epidural morphine, continuous epidural morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people
- Sponsor
- Inonu University
Spinal Cord, Epidural
Transesophageal Echocardiography (TEE): A Novel Technique for Spinal Cord Imaging
The aim of this prospective observational study is to assess whether transesophageal echocardiography (TEE) can be used to identify the structures within the vertebral foramen of the spinal column and to determine the range of…
- Trial name
- NCT02415244
- Testing
- TEE
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Kenichi Ueda
Natural Childbirth, Water Birth
Effectiveness and Safety in Maternal and Neonatal Outcomes in Water Birth.
Childbirth is a unique and non-transferable experience in the life of a woman, her partner and her family. It is a very intense process that requires accompaniment and, in the vast majority of cases, requires analgesic support in…
- Conditions
- Natural Childbirth, Water Birth, Neonatal Asphyxia, Outcome, Adverse Birth
- Trial name
- NCT06429111
- Testing
- Epidural analgesia, Immersion water
- Where
- Spain
- Volunteers
- 642 people
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Cerebral Palsy, Hip Dysplasia
Pain Injection Versus Epidural Anesthesia for Hip Surgery in Pediatric Patients With Cerebral Palsy
Pain management in pediatric patients presents a difficult challenge. Unlike adults, pediatric patients often cannot communicate their pain management needs clearly.
- Conditions
- Cerebral Palsy, Hip Dysplasia, Pain, Postoperative
- Trial name
- NCT06189781
- Testing
- Ropivacaine injection, Bupivacaine, lidocaine, ropivacaine
- Where
- 4 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of California, Los Angeles
Pectus Excavatum, Funnel Chest
Intercostal Nerve Cryoablation Versus Epidural Analgesia for Nuss Repair of Pectus Excavatum
Primary objective of the current study is to determine the impact of intercostal nerve cryoablation on postoperative length of hospital stay compared to standard pain management of young pectus excavatum patients (12-24 years)…
- Trial name
- ICE (NCT05731973)
- Testing
- Intercostal nerve cryoablation, Thoracic epidural analgesia (continuous infusion with sufentanyl (1 µg/ml) and bupivacaine (1.25 mg/ml)), Intercostal nerve block (single shot bupivacaine (1.25 mg/ml))
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Zuyderland Medisch Centrum
Low Back Pain, Radiculopathy
Comparison Between Endoscopic Epidural Neuroplasty and Percutaneous Epidural Neuroplasty in Low Back and Radicular Pain
PEN(percutaneous epidural neuroplasty) can be performed percutaneously, may be manipulated to mechanically break up adhesions by catheter, while various agents, such as anesthetics, corticosteroids, hyaluronidase, and hypertonic…
- Trial name
- NCT05533723
- Testing
- Endoscopic epidural neuroplasty, Percutaneous epidural neuroplasty (PEN)
- Where
- South Korea
- Volunteers
- 107 people
- Sponsor
- Ajou University School of Medicine
Pain, Postoperative, Anesthesia
Anaesthesiological Involvement in Postoperative Pain Treatment
This study aims to investigate the current organization and management of postoperative pain in Denmark, especially for invasive pain treatment modalities (epidural infusions, PCA and regional blocks), in a national survey…
- Conditions
- Pain, Postoperative, Anesthesia, Epidural Analgesia, Acute Pain
- Trial name
- NCT03496194
- Where
- Denmark
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Anesthesia, Local Anesthesia
Can Caudal Dexmedetomidine Provide Effective Analgesia?
The goal of this clinical trial is to evaluate if caudal dexmedetomidine can provide effective analgesia during inguinoscrotal surgeries in pediatrics, if used caudally alone (and not as an adjunct to caudal bupivacaine).
- Trial name
- NCT05902780
- Testing
- Caudal Bupivacaine injection, Caudal Dexmedetomidine Injection
- Volunteers
- 50 people
- Sponsor
- Benha University
Spinal Stenosis
Comparison of Transforaminal vs. Parasagittal Interlaminar Epidural Injection
The purpose of this study is to compare the clinical efficacy, incidence of ventral epidural spreading and provocation of concordant paresthesia, amount of radiation exposure and total procedure time between transforaminal and…
- Trial name
- NCT02838615
- Testing
- epidural steroid (dexamethasone) injection
- Volunteers
- 56 people
- Sponsor
- Keimyung University Dongsan Medical Center