Clinical trials: Epithelial-Mesenchymal Transition
Breast Cancer, Lymph Node Metastases
Role of SIRT1 in Regulation of Epithelial-to-mesenchymal Transition in Breast Cancer Lymph Nodes Metastasis
Luminal A breast cancer is a kind of breast cancer with low rate lymph node metastasis and good survival. But in clinical practice, Luminal A breast cancer can present with early, unexpected lymph node metastasis some time…
- Trial name
- NCT04137406
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Peking University People's Hospital
Urothelial Bladder Carcinoma, Bladder Carcinoma
Tumor Budding and T1 Substaging in Urothelial Bladder Cancer
Bladder cancer is a significant global and local health concern, and predicting how aggressive a patient's tumor will behave is critical for guiding treatment.
- Conditions
- Urothelial Bladder Carcinoma, Bladder Carcinoma, Non-Muscle-Invasive Bladder Cancer (NMIBC), Muscle-Invasive Bladder Cancer (MIBC)
- Trial name
- NCT07529639
- Volunteers
- 100 people
- Sponsor
- Assiut University
Solid Tumor
QUILT-3.036: AMG 337 in Subjects With Advanced or Metastatic Solid Tumors
This is a phase 2 study of AMG 337 in subjects with advanced or metastatic solid tumors that overexpress MET or harbor METex14del mutations resulting in MET exon 14 skipping.
- Trial name
- NCT03147976
- Testing
- AMG 337
- Where
- United States
- Sponsor
- NantPharma, LLC
Renal Cell Carcinoma
Moesin Expression in Clear Cell Renal Cell Carcinoma
Renal cell carcinoma (RCC) is the most frequently occurring primary renal neoplasm. There are several histological variants of RCC that are associated with variable prognostic outcomes.
- Trial name
- NCT06055660
- Testing
- Immunohistochemical detection of Moesin in Clear cell Renal Cell Carcinoma
- Volunteers
- 50 people
- Sponsor
- Sohag University
Periodontal Disease, AVDC Stage 3and 4, Epithelial Mesenchymal Transition
The Potential Association of Long Non-coding RNA (NEAT1 and MALAT1) in the Process of Epithelial-mesenchymal Transition in Periodontitis
Periodontitis is a polymicrobial, inflammatory condition affecting tooth-supporting tissues. It is characterized by a progressive loss of epithelial attachment and resorption of alveolar bone, which can lead to tooth loss.
- Conditions
- Periodontal Disease, AVDC Stage 3and 4, Epithelial Mesenchymal Transition, Long Noncoding RNA
- Trial name
- NCT05995067
- Testing
- periodontitis challenge
- Where
- Iraq
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ali A Abdulkareem