Clinical trials: Error, Refractive
Myopia
Sustained Effect of Red-light Therapy for Myopia Control: A 2-Year Post-Trial Follow-up Study
To evaluate the long-term efficacy and safety of red-light therapy for myopia control over 2 years, and the potential rebound effect after treatment cessation.
- Trial name
- NCT06232161
- Testing
- Red-light therapy device, Spectacles
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Beijing Airdoc Technology Co., Ltd.
Myopia
Myopia Control Efficacy of Second-generation DIMS Spectacle Lenses on Fast Progressing Myopes
The purpose of this study is to examine the efficacy and performance of the variant of Defocus Incorporated Spectacle lenses on controlling myopia progression in fast progressing myopic children.
- Trial name
- NCT05888792
- Testing
- Variant of Defocus Incorporated Spectacle lens (DG2)
- Where
- Hong Kong
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia
Progressive Myopia Treatment Evaluation for NaturalVue Multifocal Contact Lens Trial
This is a multi-center, randomized, double-masked clinical trial. All study devices are market approved/cleared in the localities where the study is conducted.
- Trial name
- PROTECT (NCT05159765)
- Testing
- Single vision contact lenses, Multifocal contact lenses
- Where
- 8 sites in United States, Canada and 2 more
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Visioneering Technologies, Inc
Anisometropia, Hyperopia
Effect of Light-Blocking Lenses on Hyperopic Anisometropic Children
To evaluate the effectiveness of light-blocking lenses in promoting emmetropization and reducing anisometropia in children with hyperopic anisometropia, and to assess the impact of light-intercepting lenses on visual function in…
- Trial name
- NCT07142928
- Testing
- light-blocking lenses, single-vision lenses
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Accomodation, Refractive Errors
Study on the Effect of Two Ways of Cycloplegia on Biological Parameters of Ciliary Muscle
Atropine has a ciliary muscle-paralysing effect and causes hyperopic drift. Besides, atropine has been proven to slow the progression of myopia. Many studies have suggested that atropine can increase the thickness of the choroid.
- Conditions
- Accomodation, Refractive Errors, Myopia, Cycloplegia
- Trial name
- NCT05449015
- Testing
- 1% atropine
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Refractive Error
First-Sight Refractive Error Correction: Direct Comparison to Autorefraction Results in Children 7 to 18 Years of Age
Proof of concept study to compare the best corrected visual acuity obtained via First-Sight lenses with the autorefraction in children.
- Trial name
- NCT01365884
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Myopia, Progressive
Near Horizontal Heterophoria in Chinese Children
This study aimed to assess the association of refraction and axial length with near-horizontal heterophoria in a large population-based study of school-aged Chinese children.
- Trial name
- NCT05007626
- Testing
- axial length and refractive error
- Where
- China
- Volunteers
- 15,081 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia
Effect of Preoperative Pupil Size on Quality of Vision After Wavefront-Guided LASIK
The purpose of this study is to evaluate whether the size of the pupil has an effect on quality of vision in patients undergoing LASIK surgery.
- Trial name
- NCT00889941
- Testing
- LASIK
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Stanford University
Myopia, Child Myopia Progression
Photolithography Microstructure Myopia Management Lenses in Preventing and Controlling Myopia in Children and Adolescents
Evaluate the effectiveness of different lithographic microstructured myopia management lenses in controlling the progression of myopia in children and adolescents, as well as the safety and comfort of wearing them.
- Trial name
- NCT07514039
- Testing
- Myopia management lens
- Where
- China
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia
Ophthalmic Compatibility During Seven Days of Continuous Wear of Silicone Hydrogel Lenses
The purpose of this study is to assess the ophthalmic compatibility of three different silicone hydrogel lenses worn on an overnight basis for six nights.
- Trial name
- QUINCE (NCT00934102)
- Testing
- Narafilcon A contact lens, Lotrafilcon A contact lens, Galyfilcon A contact lens
- Where
- Canada
- Volunteers
- 57 people
- Sponsor
- CIBA VISION
Precocious Puberty, Early Puberty
Effect of Exogenous Growth Hormone on Ocular Findings
Body size and eye function play an essential role in adapting to the environment and human survival. Growth hormone is commonly recognized by its effect on the height of individuals; Although from an evolutionary perspective, the…
- Conditions
- Precocious Puberty, Early Puberty, Refraction Error
- Trial name
- NCT05338411
- Where
- 2 sites in Iran
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Amblyopia, Myopia
Performance of a Photoscreener for Vision Screening in a Haitian Pediatric Population
Screening of haitian children between the ages of 3 and 6 years old for amblyogenic risk factors with the use of the Spot photoscreener. The photoscreener results will be compared to the complete ophthalmologic evaluation.
- Conditions
- Amblyopia, Myopia, Hyperopia, Astigmatism
- Trial name
- POPH (NCT02655432)
- Testing
- Spot photoscreener, Ophthalmologic evaluation, Cyclopleged refraction
- Where
- 3 sites in Haiti
- Volunteers
- healthy volunteers welcome
- Sponsor
- Université de Montréal
Myopia
Brimonidine Eye Drops in the Prevention of Myopia Progression
Study to determine the efficacy of alpha-2 adrenergic drugs (brimonidine) in the prevention of myopia progression. Given that the drugs used so far have limited efficacy and side effects (loss of near vision, photophobia), it may…
- Trial name
- NCT06996236
- Testing
- Treatment with brimonidine eye drops 0.025%
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Refractive Error
The Evolutionary Model of Mild-to-moderate Myopia in China
Myopia has emerged as a major health issue in east Asia, because of its increasingly high prevalence in the past few decades (now 80-90% in school-leavers), and because of the sight-threatening pathologies associated with high…
- Trial name
- NCT02667509
- Where
- China
- Volunteers
- 852,441 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Myopia, Progressive
To Evaluate the Efficacy and Safety of an Defocus Lens in Slowing the Progression of Myopia
To confirm the efficacy of DIMS lenses in controlling myopia progression, we planned a prospective, single-centre, randomised, double-blind, controlled, non-inferiority clinical study.
- Trial name
- NCT06405711
- Testing
- frame lens
- Where
- China
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Pediatric Cataract, Congenital Cataract
Toric Intraocular Lens Implantation for Pediatric Aphakia
Here, we conducted a nonrandomized clinical trial aims to evaluate and compare the prognosis of visual function in children of these two types of IOL implantation over a three-year postoperative period.
- Trial name
- NCT07088796
- Testing
- Toric IOL implantation, Non-toric IOL implantation
- Where
- China
- Volunteers
- 236 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Hyperopia and Myopia
Eye Imaging for the Study of Childhood Myopia
Myopia (nearsightedness) is increasing worldwide and is becoming a serious public health problem. Studies estimate that by 2050, if no action is taken, almost half of the world's population will be myopic.
- Trial name
- SELENA (NCT07335146)
- Testing
- Ophtalmic measurements to estimate geometrical distances, MRI, Ophtalmic measurements to measure wavefront aberrations
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Essilor International
Anisometropia
Ten-year Follow-up of Laser in Situ Keratomileusis in Patients 8 to 15 Years Old
The purpose of this study is to determine the safety, efficacy, predictability, and stability of laser in situ keratomileusis (LASIK) to correct high anisometropia in patients 8 to 15 years old in whom conventional treatments…
- Trial name
- NCT00800774
- Testing
- LASIK
- Where
- Brazil
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Instituto de Olhos de Goiania
Myopia, Progressive
Novel Lenses for Myopia Progression Trial
This is a multi-center , prospective, randomised, longitudinal study to evaluate rate of myopia progression with novel lenses compared to Single-Vision spectacles.
- Trial name
- NCT06563700
- Testing
- spectacle lens, single vision lens
- Where
- China
- Volunteers
- 342 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia
Comparative Clinical Evaluation of Daily Disposable Lenses in Symptomatic Lens Wearers
The purpose of this trial is to evaluate the extent to which symptoms improve in symptomatic contact lens wearers when fit with one of 5 different daily disposable contact lenses.
- Trial name
- NCT00953407
- Testing
- Nelfilcon A contact lens, Narafilcon A contact lens, Etafilcon A contact lens
- Volunteers
- 128 people
- Sponsor
- CIBA VISION