Clinical trials: Estrogen Activity
Hormone
Effects of Infant Diets on Estrogen Activity and Development
This study, conducted at the Children's Hospital of Boston and the Brigham and Women's Hospital in Boston, will examine the natural history of infant development in the first year of life and how different types of infant feeding…
- Trial name
- NCT00340652
- Where
- 2 sites in United States
- Volunteers
- 157 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Contraception
International Active Surveillance Study: Safety of Estrogen Estetrol (E4) Contraceptive Study (INAS-SEECS)
The combined oral contraceptive (COC) containing estetrol (E4) and drospirenone (DRSP) (E4/DRSP) is a novel oral contraceptive containing a fixed dose of E4 (14.2 mg) and DRSP (3 mg).
- Trial name
- INAS-SEECS (NCT06186271)
- Where
- Germany
- Volunteers
- 68,100 people
- Sponsor
- Center for Epidemiology and Health Research, Germany
Contraception
International Active Surveillance Study - Safety of Contraceptives: Role of Estrogens
The primary objective of the study is to assess the risks of short and long-term use of estradiol valerate/dienogest (EV/DNG) and of established oral contraceptives (OCs) in a study population that is representative for the…
- Trial name
- INAS-SCORE (NCT01009684)
- Where
- Germany
- Volunteers
- 50,203 people, healthy volunteers welcome
- Sponsor
- Center for Epidemiology and Health Research, Germany
Systemic Lupus Erythematosus
Serologically Active, Clinically Stable Systemic Lupus Erythematosus
The first part of this study will use the database of a large, ongoing NIH-sponsored lupus study, Safety of Estrogen in Lupus Erythematosus National Assessment.
- Trial name
- SACS-SLE (NCT00000421)
- Testing
- Prednisone
- Where
- 3 sites in United States
- Volunteers
- 154 people
- Sponsor
- NYU Langone Health
Cerebral Blood Flow, Cerebral Blood Flow Regulation
The Role of Estrogen and Testosterone in Determining Brain Blood Flow and Metabolic Regulation in Humans
Due to historical exclusion of females from research, there are gaps in the understanding of female physiology, how it differs from males, and how sex-specific hormones contribute.
- Conditions
- Cerebral Blood Flow, Cerebral Blood Flow Regulation, Sex Differences, Exercise
- Trial name
- NCT07212712
- Testing
- GnRH antagonist, Estradiol (E2), Testosterone
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Depressive Disorder, Mood Disorder
Progestin (Progesterone-Like Hormones) Induced Dysphoria (Depressed Mood, Irritability, Anxiety)
Often women are prescribed hormone replacement therapy (HRT) during the perimenopause or menopause. Hormone replacement therapy includes both estrogen and progesterone.
- Conditions
- Depressive Disorder, Mood Disorder, Psychomotor Agitation
- Trial name
- NCT00001770
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Infant Formula, Estrogen Activity
Study of Infant Diets on Estrogen Activity and Development
This study, conducted at the University of Pennsylvania s Newborn Nursery, the Children s Hospital of Philadelphia, and the Exton Specialty Care Center, will examine how different infant diets may affect estrogen activity in…
- Trial name
- NCT00340665
- Where
- 2 sites in United States
- Volunteers
- 239 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Anorexia in Adolescence
Effect of Aerobic Exercises and Nutrition In Adolescent Girls With Anorexia
Randomized control study used to identify the effect of aerobic exercises on the activity of daily living and estradiol serum level in young girls with anorexia
- Trial name
- NCT05057000
- Testing
- aerobic exercises + Diet, diet proram
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Badr University
Contraception, Birth Control
International Active Surveillance Study: Native Estrogen Estetrol (E4) Safety Study
Multinational, comparative, prospective, active surveillance study that follows two cohorts. The primary objective of the study is to characterize and compare the risks of E4/Drospirenone (DRSP) with levonorgestrel-containing…
- Trial name
- INAS-NEES (NCT06028555)
- Where
- Germany
- Volunteers
- 101,000 people, healthy volunteers welcome
- Sponsor
- Center for Epidemiology and Health Research, Germany
Postmenopause
Use of the Synthetic Hormone CDB-2914 in Treating Symptoms of Menopause
This study will examine the safety and effectiveness of a synthetic hormone, CDB-2914, for treating symptoms of menopause. It will compare the effects of estrogen and CDB-2914 with those of estrogen and progesterone in…
- Trial name
- NCT00009659
- Testing
- CDB 2914
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)