Clinical trials: Executive Dysfunction
Cognitive Impairment, Child Autism
Exercise and Cognition in Children With ASD
Physical exercise is widely reported to be beneficial to executive functions (EFs) in children with autism spectrum disorder (ASD).
- Trial name
- NCT05503459
- Testing
- Bicycle learning, Stationary cycling
- Where
- Hong Kong
- Volunteers
- 82 people
- Sponsor
- Education University of Hong Kong
Executive Dysfunction, Occupational Problems
Investigation of the Relationship Between Executive Functions and Occupational Performance of Children With Duchenne Muscular Dystrophy
The effects of Duchenne muscular dystrophy and its treatments on executive functions and occupational performance are under-mentioned in the literature.
- Conditions
- Executive Dysfunction, Occupational Problems, Duchenne Muscular Dystrophy
- Trial name
- NCT06868784
- Testing
- Evaluations
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Lokman Hekim University
Child Behavior, Problem Behavior
Executive Function and Symptom Reduction in Youth Receiving Home-based Treatment With Collaborative Problem Solving
In this project, the investigators will extend prior results of parent-reported executive function growth and symptom reduction in children receiving home-based treatment with the Collaborative Problem Solving treatment approach…
- Conditions
- Child Behavior, Problem Behavior, Executive Dysfunction
- Trial name
- NCT04121650
- Testing
- Collaborative Problem Solving
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Massachusetts General Hospital
Childhood Cancer, Cognitive Impairment
Cognitive and Motor Training in Pediatric Posterior Fossa Tumor Survivors
The purpose of this study is to create a rehabilitation program for children who survived posterior fossa tumors using the latest technology.
- Conditions
- Childhood Cancer, Cognitive Impairment, Motor Skills Disorders, Posterior Fossa Tumor
- Trial name
- NCT03951246
- Testing
- Cognitive and Motor Training
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Federal Research Institute of Pediatric Hematology, Oncology and Immunology
Executive Dysfunction
Development and Pilot Testing of a Novel Preschool Executive Function Curriculum
Executive function (EF) skills are a set of essential cognitive abilities that enable individuals to demonstrate their knowledge and talents, effectively complete tasks and navigate social interactions through flexible regulation…
- Trial name
- NCT05135728
- Testing
- Unstuck and On Target: Preschool
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Children's National Research Institute
Schizophrenia, Neurocognitive Disorders
Goal Management Training for Patients With Schizophrenia or High Risk for Schizophrenia
About 85% of patients with schizophrenia have cognitive impairments, executive functions being particularly affected. Executive dysfunction, and cognitive deficits in general, are important predictors of functional outcomes…
- Trial name
- NCT03048695
- Testing
- GMT
- Where
- Norway
- Volunteers
- 83 people
- Sponsor
- Sykehuset Innlandet HF
Acquired Brain Injury, Cognitive Symptom
CBCR for Executive Functions in Patients With ABI in the Chronic Phase
This study examines the effects of computerbased cognitive rehabilitation on executive functions in the chronic phase after acquired brain injury
- Conditions
- Acquired Brain Injury, Cognitive Symptom, Executive Dysfunction
- Trial name
- NCT03558308
- Testing
- Computer based cognitive rehabilitation
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Katrine Sværke
Cognitive Deficit in Attention, Executive Dysfunction
Maternal Choline Supplementation and Offspring Cognition in Adolescence
The goal of this 13-year follow up of a randomized control trial is to study the effect of maternal choline supplementation on offspring cognition in adolescence.
- Conditions
- Cognitive Deficit in Attention, Executive Dysfunction, Emotional Regulation
- Trial name
- CholTeens (NCT05859126)
- Testing
- Maternal Choline Supplementation 930 mg/d, Maternal Choline Supplementation 480 mg/d
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cornell University
Behavior, Child, Disruptive Behavior
Randomized Controlled Trial of a Behavioral Training App
The investigators propose addressing and evaluating the efficacy of a behavioral, contingency management app by conducting a randomized controlled trial (RCT) that will evaluate the app compared to a placebo app control group.
- Conditions
- Behavior, Child, Disruptive Behavior, Executive Dysfunction, Attention-deficit
- Trial name
- NCT06447909
- Testing
- Treatment App
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- New York University
Autism Spectrum Disorder, Mental Health Disorder
Adaptation and Implementation of an ASD Executive Functioning Intervention in Children's Mental Health Services
The purpose of this project is to conduct a feasibility test of an ASD executive functioning intervention adapted for mental health settings, including examining the effectiveness and process of implementing this adapted…
- Conditions
- Autism Spectrum Disorder, Mental Health Disorder, Executive Dysfunction
- Trial name
- NCT04295512
- Testing
- Unstuck and on Target
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- San Diego State University
Dyslexia, Executive Dysfunction
The Effects of Play and Competition-Based Cognitive Therapy
Purpose: The aim of this study was to investigate the effects of play and competition-based cognitive therapy (PCB-CT) on executive function and occupational routines in children with dyslexia.
- Trial name
- NCT03906097
- Testing
- Play and Competition-Based Cognitive Therapy
- Volunteers
- 64 people
- Sponsor
- Hacettepe University
Memory Impairment, Executive Dysfunction
The Effects of Playing High School Football on Later Life Cognitive Functioning and Mental Health
The purpose of this study is to assess the effect of playing high school football on later in life cognitive functioning and mental health.
- Conditions
- Memory Impairment, Executive Dysfunction, Depression
- Trial name
- NCT02833129
- Volunteers
- 3,904 people
- Sponsor
- University of Pennsylvania
Attention Deficit Hyperactivity Disorder
Metabolic Pathway of Tryptophan and Executive Dysfunction in Children With Attention Deficit Hyperactivity Disorder
The present project is to identify the relationship between ADHD and the metabolites of tryptophan.
- Trial name
- NCT03901859
- Where
- Taiwan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
HIE - Hypoxic - Ischemic Encephalopathy, Perinatal Anoxic-ischemic Brain Injury
Biomarkers Study in Infants With Prior Neonatal Brain Injury
This research focuses on the long-term cognitive development of children, including healthy infants and those who had a perinatal brain injury.
- Conditions
- HIE - Hypoxic - Ischemic Encephalopathy, Perinatal Anoxic-ischemic Brain Injury, Premature Birth, Healthy Participants
- Trial name
- NCT07413900
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Fetal Alcohol Spectrum Disorders
Cognitive Training and tDCS for Children With FASD
This is a randomized placebo-controlled trial of cognitive training with transcranial direct current stimulation (tDCS) for children and adolescents (ages 10 - 16 years) with prenatal alcohol exposure (PAE).
- Trial name
- NCT03361293
- Testing
- Active tDCS, Cognitive training
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Minnesota
Epilepsy in Children, Executive Dysfunction
Epilepsy Journey-An Executive Functioning Intervention for Teens With Epilepsy
The goal of this multi-site clinical trial is to determine the effectiveness of two components of a web-based intervention (Epilepsy Journey) to improve executive functioning in adolescents with epilepsy.
- Trial name
- NCT06608966
- Testing
- Epilepsy Journey web-based modules, Telehealth with a therapist
- Where
- 3 sites in United States
- Volunteers
- 310 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Attention Deficit Hyperactivity Disorder, Executive Dysfunction
Executive Control Training for Adolescents With ADHD: A Randomized Controlled Effectiveness Trial
The goal of this clinical trial is to evaluate an evidence-based, non-pharmacological treatment alternative: Goal Management Training (GMT) for adolescents with Attention-Deficit/Hyperactivity Disorder (ADHD).
- Trial name
- ADHD Effect (NCT05874791)
- Testing
- Goal Management training
- Where
- 2 sites in Norway
- Volunteers
- 120 people
- Sponsor
- Sykehuset Innlandet HF
Precocious Puberty, Central, Executive Dysfunction
Hypiend - Multicomponent Behavioral Intervention in Pre-puberal Children (Hypiend-PPC)
This study is part of the European Hypiend project, which aims to explore the effects of co-exposure to endocrine-disrupting chemicals (EDCs) on the function and epigenetic programming of the hypothalamic-pituitary-adrenal (HPA)…
- Trial name
- Hypiend-PPC (NCT07411001)
- Testing
- Multi-Component Behavioral intervention, Information
- Where
- Belgium
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Sciensano
Impulsive Aggression, ADHD
Dialectical Behavioral Therapy Skills for Impulsive Aggression
This trial aims to Study the efficacy of DBT skills for impulsive aggression and executive dysfunctions in drug naïve children who are presented with impulsive aggression and ADHD and attending Child and adolescent clinic at…
- Conditions
- Impulsive Aggression, ADHD, Executive Dysfunction
- Trial name
- NCT05351944
- Testing
- Dialectical behavioral therapy skills for the intervention experimental group A, psychoeducation or Atomoxetine or stimulants according to ADHD severity
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Alexandria University
Sickle Cell Disease, Executive Dysfunction
Methylphenidate to Address Attention and Executive Deficits Among Children With Sickle Cell Disease
The purpose of this study is to determine if patients with sickle cell disease (SCD) can consistently take a drug called Methylphenidate (MPH) daily, once a day for 4 weeks to help with any thinking, attention or schoolwork…
- Conditions
- Sickle Cell Disease, Executive Dysfunction, Cognitive Impairment, Attention Deficit/Hyperactivity Disorder (ADHD)
- Trial name
- NCT07226219
- Testing
- Extended-Release Methylphenidate
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- St. Jude Children's Research Hospital