Clinical trials: Executive Dysfunction
Cognitive Impairment, Autoimmune Encephalitis
To Explore Cognitive Neural Mechanism of Autoimmune Encephalitis by Using Neuropsychological Tests and Multi-modal MRI
Most of patients with autoimmune encephalitis are left with permanent cognitive deficits of varying severity. The patients' life and career would be affected definitely by cognitive deficits.
- Trial name
- NCT03530462
- Testing
- rituximab, cyclophosphamide, Steroids
- Where
- China
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Autism Spectrum Disorder, Executive Dysfunction
Transcranial Direct Current Stimulation in Children With Autism
Although many children diagnosed with autism spectrum disorder (ASD) make significant progress in learning and their cognitive skills improve with applied behavior analysis (ABA), there are a significant number of children who…
- Trial name
- tDCS (NCT07092280)
- Testing
- Active tDCS
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- New York State Institute for Basic Research
Executive Dysfunction, ASD
Effect of rTMS on the Abnormal Executive Function of ASD Children
In this study, the investigators will explore the effects of repetitive transcranial magnetic stimulation (rTMS) on executive function deficits in high function autism spectrum disorder.
- Trial name
- NCT04237870
- Testing
- Active cTBS
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Executive Dysfunction, Motor Activity
The Role of Brain-derived Neurotropic Factor in the Relationship Between Executive Function and Physical Training
This doctoral thesis has the aim to identify the role of Brain-derived neurotropic factor in the relationship between physical fitness/activity and executive functions in typically developing children and children with Autism…
- Conditions
- Executive Dysfunction, Motor Activity, Child
- Trial name
- NCT02503579
- Testing
- physical training
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University Ghent
Autism Spectrum Disorder, Asthma
Folic Acid Clinical Trial: Follow up of Children (FACT 4 Child)
FACT 4 Child is a follow up study of mothers who participated in the Folic Acid Clinical Trial (NCT01355159) and their children at 4-6 years of age to determine the effect of high dose folic acid supplementation on social…
- Conditions
- Autism Spectrum Disorder, Asthma, Executive Dysfunction, Emotional Problem
- Trial name
- NCT03269110
- Testing
- SRS 2, CBCL, BRIEF-P
- Where
- 58 sites in Australia, Canada and 2 more
- Volunteers
- 664 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Executive Function Disorder, Emotional Regulation
Evaluation of Executive Function and Emotional Regulation in Children in Bangladesh
The study explores the impact of malnutrition at enrollment on executive function (EF) and emotional regulation (ER) in malnourished 1-year-old children and whether specially designed brain directed therapeutic feeds improve…
- Conditions
- Executive Function Disorder, Emotional Regulation, Malnutrition, Child
- Trial name
- NCT05629624
- Testing
- Chickpea based RUSF, E-RUSF, Outcome reference group/RUSF
- Where
- Bangladesh
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Heart Defect, Congenital, Executive Dysfunction
Executive Function Intervention for Children With Complex Congenital Heart Disease
Children with complex congenital heart disease (cCHD) nowadays survive thanks to medical advances into their teenage years and adulthood. However, many of them have difficulties with so-called executive functions.
- Trial name
- E-Fit Heart (NCT07692958)
- Testing
- E-Fit Intervention
- Where
- Switzerland
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Bea Latal
Sickle Cell Disease, Cognitive Impairment
Cognitive Remediation Intervention to Prepare for Transition of Care
Randomized Controlled Trial (RTC) testing the efficacy of a telehealth adaptation of the Cognitive-Remediation of Executive and Adaptive Deficits in Youth (C-READY) intervention to prepare adolescents with sickle cell disease for…
- Conditions
- Sickle Cell Disease, Cognitive Impairment, Adolescent Behavior, Self Efficacy
- Trial name
- NCT05336201
- Testing
- CREADY (Cognitive-Remediation of Executive and Adaptive Deficits in Youth)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Alabama at Birmingham
Executive Dysfunction, Physical Stress
Integrative Adolescence Research Programme (IARP)
This study aims to understand child health during adolescence. We will examine the role of lifestyle (e.g. physical activity), growth trajectories and other environmental factors that can influence the development of phenotypes…
- Conditions
- Executive Dysfunction, Physical Stress, Mental Health Wellness 1
- Trial name
- IARP (NCT06622681)
- Testing
- No intervention
- Where
- 2 sites in Singapore
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Institute for Human Development and Potential (IHDP), Singapore
Epilepsy, Quality of Life
Idiopathic Generalized Epilepsy Cognitive and Emotional Profile
The primary goal of the study is to explore the neurocognitive, emotional-behavioral functioning, and quality of life of adolescents with IGE, identifying key factors that affect their overall well-being.
- Conditions
- Epilepsy, Quality of Life, Neuropathology, Emotional Problem
- Trial name
- NCT06782074
- Testing
- emotional and neuropsychological assessment
- Where
- Italy
- Volunteers
- 96 people
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
HIV Infections, Exposure During Pregnancy
Neuropsychological Development and Executive Functioning of Children Born to HIV- Infected Mothers ( NEUROPSY-HEU )
Main objective: to evaluate the executive functioning of the HIV exposed uninfected children (HEU) versus children from the same socio-economic and cultural environment, not infected or affected by HIV.
- Conditions
- HIV Infections, Exposure During Pregnancy, Neurophysiologic Abnormality, Executive Dysfunction
- Trial name
- NEUROPSY-HEU (NCT04108728)
- Testing
- BRIEF SCORE AT INCLUSION
- Where
- 3 sites in France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Executive Dysfunction, Autism Spectrum Disorder
Intervention-Induced Plasticity of Flexibility and Learning Mechanisms in ASD
This project explores the association between learning and cognitive flexibility by testing whether a cognitive behavioral intervention designed to improve flexibility in ASD changes learning and associated neural activation…
- Conditions
- Executive Dysfunction, Autism Spectrum Disorder, Adolescent Behavior
- Trial name
- NCT05131659
- Testing
- Executive function group therapy
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- Children's National Research Institute
ADHD, Inattention
Intensive-neurofeedback Protocol for Children With ADHD: A Proof-of-concept Study Comparing iAPF-personalized and Standard Theta-beta-ratio Training
The first aim of this clinical trial is to test the feasibility and signal validity of a new approach to neurofeedback training (NF) using intensive EEG-based theta-beta NF for children with ADHD in the context of NF camps during…
- Conditions
- ADHD, Inattention, Hyperactivity, Impulsivity
- Trial name
- NCT07595783
- Testing
- Standard TBR-NF, iAPF -TBR-NF
- Where
- 2 sites in Germany
- Volunteers
- 40 people
- Sponsor
- Bielefeld University
Autism Spectrum Disorder, Executive Dysfunction
Non-invasive Brain Stimulation in Children With Autism
Although many children diagnosed with autism spectrum disorder (ASD) make significant progress in learning and their cognitive skills improve with applied behavior analysis (ABA), there are a significant number of children who…
- Conditions
- Autism Spectrum Disorder, Executive Dysfunction, Child Autism
- Trial name
- NCT05105126
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Sponsor
- Rutgers, The State University of New Jersey
Virtual Reality, Developmental Coordination Disorder
Effects of VR in Children With DCD: Randomized Controlled Trial
The aim of the study is to examine the effect of VR application on motor, cognitive and sensory-perceptual skills, and activity and participation levels in children with DCD.
- Conditions
- Virtual Reality, Developmental Coordination Disorder, Visual Perceptual Weakness, Motor Skills Disorders
- Trial name
- NCT06246318
- Testing
- virtual reality, conventional occupational therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Hacettepe University
Executive Dysfunction, Autism Spectrum Disorder
A Hybrid Effectiveness-implementation Trial of a High School-based Executive Function Treatment for Autistic Youth
This study will test the effectiveness of a school-based cognitive behavioral executive function (EF) intervention, Unstuck \& On Target High School (UOT:HS), for transition-age youth with autism spectrum disorder (ASD).
- Conditions
- Executive Dysfunction, Autism Spectrum Disorder, Adolescent Behavior
- Trial name
- NCT05017779
- Testing
- Unstuck & On Target: High School, Treatment as Usual
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- Children's National Research Institute
Executive Dysfunction, Attention Deficit Hyperactivity Disorder
HOPS Study: A Conceptual Replication
The purpose of this current study is to conduct a conceptual replication with an independent evaluation team of the randomized controlled trial conducted by Langberg and colleagues, which demonstrated the efficacy of the…
- Trial name
- NCT04465708
- Testing
- Homework, Organization, and Planning Skills
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Cognitive Orientation, Executive Dysfunction
THE EFFECT OF THE COGNITIVE ORIENTATION TO DAILY OCCUPATIONAL PERFORMANCE (CO-OP) APPROACH IN CHILDREN WITH ATTENTION DEFICIT AND HYPERACTIVITY DISORDER ON MOTOR PERFORMANCE AND EXECUTIVE FUNCTIONS
Attention deficit and hyperactivity disorder (ADHD) is a behavioural and neurodevelopmental disorder that can affect behavioural, emotional, academic, social, and cognitive functions and is not age-appropriate.
- Conditions
- Cognitive Orientation, Executive Dysfunction, Motor Activity
- Trial name
- NCT05125120
- Testing
- COGNİTİVE ORİENTATİTON DAİLY OCCUPATİONAL PERFORMANCE APPROACH
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Exercise, ADHD
Exercise Enhances Brain Function in Attention-deficit/Hyperactivity Disorder (ADHD)
The aim of the study was to investigate the different effects of exercise types on inhibitory control in children with attention-deficit/ hyperactivity disorder.
- Conditions
- Exercise, ADHD, Executive Dysfunction
- Trial name
- NCT05016102
- Testing
- Exercise type
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Executive Function Disorder, Strength Training
Strength Training and Executive Functions: A Randomized Controlled Trial
A group of 50 age-schooled adolescents was randomized into one intervention and another control group of 25 subjects each. After estimating one maximum repetition for all the participants in a previous session, the intervention…
- Conditions
- Executive Function Disorder, Strength Training, Adolescent Behavior, Academic Achievement
- Trial name
- ASTOEF (NCT04488445)
- Testing
- Strength training, Stretch and balance training
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza