Clinical trials: Executive Functions
Healthy Volunteers
Acute Effects of High-intensity Interval Training With Mindfulness-based Recovery on Executive Function in Children
The goal of this randomized cross-over trial is to learn about the effect of a single bout of 20-min mindfulness-based high-intensity interval training (MF-HIIT), MF-only, and HIIT-only in relative to sitting rest on executive…
- Trial name
- NCT06270589
- Testing
- MF-HIIT, MF-only, HIIT-only
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Purdue University
Attention Deficit Hyperactivity Disorder (ADHD)
Home-Based Executive Function Training Intervention For Attention-Deficit/ Hyperactivity Disorder-prone Children
This study aims to investigate the effectiveness of a home-based executive function training Intervention on children's ADHD symptoms, executive function and parents' parenting stress.
- Trial name
- NCT06950866
- Testing
- Home-based executive function training therapy
- Volunteers
- 100 people
- Sponsor
- Wuhan Mental Health Centre
Healthy Volunteers
Classroom Break, Cognition, and Fitness in Elementary School Children
The goal of this randomized controlled trial is to learn about the effect of a 12-week school-based intervention combining mindfulness with high-intensity interval training (MF-HIIT), MF-only intervention, and HIIT-only…
- Trial name
- NCT06258941
- Testing
- MF-HIIT, HIIT-only, MF-only
- Where
- United States
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- Purdue University
Menstrual Cramps
Intervention in Executive Functions and Emotional Self-Regulation in Adolescents With Primary Dysmenorrhea
Primary dysmenorrhea is one of the most common gynecological conditions during adolescence and is associated not only with recurrent menstrual pain, but also with emotional disturbances and difficulties in behavioral regulation.
- Trial name
- CALMA (NCT07555886)
- Testing
- Cognitive restructuring techniques and psychoeducation to improve coping strategies for menstrual pain.
- Where
- Mexico
- Volunteers
- 35 people
- Sponsor
- Universidad Autonoma de Baja California
Epilepsy in Children, Executive Dysfunction
Epilepsy Journey-An Executive Functioning Intervention for Teens With Epilepsy
The goal of this multi-site clinical trial is to determine the effectiveness of two components of a web-based intervention (Epilepsy Journey) to improve executive functioning in adolescents with epilepsy.
- Trial name
- NCT06608966
- Testing
- Epilepsy Journey web-based modules, Telehealth with a therapist
- Where
- 3 sites in United States
- Volunteers
- 310 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
ADHD
Effect of Risperidone on Cognitive Functions in Adolescents With ADHD and Behavioral Disturbances
Introduction: The use of low dose risperidone and other antipsychotic drugs off-label as augmentation treatment for adolescents with Attention Deficit Hyperactivity Disorder (ADHD) and Disruptive Behavioral Disorder (DBD) has…
- Trial name
- NCT02906501
- Testing
- The Penn Web-Based Computerized Neurocognitive Battery, The Iowa Gambling Test (IGT)
- Where
- Israel
- Volunteers
- 45 people
- Sponsor
- Shalvata Mental Health Center
ADHD
Experimental Research on the Training of Executive Functions Through the APP "The Apollo & Rosetta Adventures" (E-FAR) in Children with ADHD (8-13 Yrs)
ADHD is one of the most prevalent neurodevelopmental disorders, with a strong impact on general functioning and in daily life. Executive Functions play an important role on this disorder, and numerous treatments have been…
- Trial name
- E-FAR (NCT06881719)
- Testing
- The Adventures of Apollo & Rosetta
- Where
- 2 sites in Italy
- Volunteers
- 35 people
- Sponsor
- University of Milano Bicocca
Obesity
The Influence of Obesity on Level of Depression and Cognitive and Executive Functions
The proposed study is a randomized, open, comparative research involving an intervention group and two control groups. The aims of the study are: 1.To compare levels of depression in female adolescents with obesity and a control…
- Trial name
- NCT03087994
- Testing
- Nutritional guidance intervention
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Healthy
Executive Training and Brain in Adolescent
The purpose of this study is to investigate the cognitive and brain effects of inhibitory control (IC) training at adolescence.
- Trial name
- APEX-ADO (NCT03084848)
- Testing
- Training
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Autism Spectrum Disorder
Augmented Reality for Behavior and Executive Function of Children With Autism Spectrum Disorder
The aim of the study is to determine the effects of usage of augmented reality for Restricted and repetitive behavior and executive function of children with autism spectrum disorder
- Trial name
- NCT05962047
- Testing
- Games of WonderTree Augmented Reality, Traditional therapy
- Where
- Pakistan
- Volunteers
- 18 people
- Sponsor
- Riphah International University
Attention Deficit/Hyperactivity Disorder
Structural and Functional Connectivity of Frontostriatal and Frontoparietal Networks as Endophenotypes of ADHD
Attention deficit/hyperactivity disorder (ADHD) is a common, impairing, clinically and genetically heterogeneous neuropsychiatric disorder with lifelong executive dysfunctions.
- Trial name
- NCT01682915
- Where
- Taiwan
- Volunteers
- 240 people
- Sponsor
- National Taiwan University Hospital
Intracranial Central Nervous System Disorder, Mental Disorder
Test of A Model of Representational Knowledge Stored in the Human Prefrontal Cortex
This study will examine the underlying mental processes that determine how people understand social behavior, remember information, and think.
- Conditions
- Intracranial Central Nervous System Disorder, Mental Disorder, Healthy
- Trial name
- NCT00024908
- Where
- United States
- Volunteers
- 949 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Phenylketonuria, Behavior and Behavior Mechanisms
Evaluation of Behavior, Executive Function, Neurotransmitter Function and Genomic Expression Kuvan Nonresponders
This observational study seeks to establish evidence: 1. that physiologic changes, unrelated to effect on the Phenylalanine Hydroxylase (PAH) enzyme, occur in Phenylketonuria (PKU) patients who are treated with sapropterin…
- Conditions
- Phenylketonuria, Behavior and Behavior Mechanisms, PAH Gene Expression
- Trial name
- IST (NCT01274026)
- Testing
- sapropterin dihydrochloride
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Tulane University School of Medicine
Cerebral Palsy
A Study Protocol for an Online Intervention to Promote School Engagement
Cerebral Palsy (CP) is a neurological, non-progressive, and permanent developmental disorder that mainly affects movement and posture, with a prevalence of 3 to 4 children per 1000 live births.
- Trial name
- NCT04247516
- Testing
- Online-intervention group I (IGI), Online-intervention group II (IGII)
- Where
- Portugal
- Volunteers
- 60 people
- Sponsor
- University of Minho
General Population of Children Aged 3 to 5 Years Old
Early Development of Academic Skills in the Classroom
This is a two-arm cluster randomized controlled trial. The two arms will be: 1) Intervention group, where the stimulation program will be implemented; and 2) Comparison group (active).
- Trial name
- JAPI (NCT05224700)
- Testing
- JAPI, Painting group
- Volunteers
- 754 people, healthy volunteers welcome
- Sponsor
- University of Talca
Executive Function of School-aged Children With ASD
VR Executive Training of School-aged Children With ASD
Many studies support that children with autism spectrum disorder (ASD) show executive dysfunction. The applicant's NSC project report also indicated that in all areas in the behavior rating inventory of executive function, the…
- Trial name
- NCT06130293
- Testing
- VR game intervention
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan Normal University
Executive Function, Motor Skills
Influence of a Parent-mediated mHealth Motor Skill Intervention on Preschool Children's Motor Skills and Cognitive Function
The proposed study uses a mHealth application "app" to help parents teach their preschool-age child motor skill (FMS) activities in the home environment.
- Conditions
- Executive Function, Motor Skills, Healthy
- Trial name
- COSMIC (NCT07680075)
- Testing
- COSMIC
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Broad Autism Phenotype
Physical Exercise Training to Enhance Executive and Social Functions
Background and study aims: Executive functions (EF) and social functions are important for self-regulation, problem solving, and attaining future goals yet they are impaired in Autism Spectrum Disorder (ASD).
- Trial name
- NCT04896671
- Testing
- Physical exercise (running on a treadmill)
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Diet Habit, Cognitive Control
Correlational and Intervention Effects of Egg Consumption on Macular Carotenoids, Cognition, and Achievement During Childhood
The aim of this study is to examine the correlational and intervention effects of egg consumption on macular carotenoids, cognition, and achievement during childhood.
- Trial name
- SHELL (NCT03521349)
- Testing
- Whole Egg Intervention, Egg White Control
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Preschool Children, Executive Function
Influence of Preschool Children's Fundamental Movement Skills, Physical Activity, and Physical Fitness on Executive Function: A Prospective Observation Study
Background: Early childhood is the most critical and rapid period of complete and healthy physical and cognitive development in human life.
- Conditions
- Preschool Children, Executive Function, Fundamental Movement Skills, Physical Activity
- Trial name
- NCT05290584
- Where
- 2 sites in China
- Volunteers
- 505 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University